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Catalog:
A2103
Brand:
Selleck
Overview
Molecular Weight
150 kDa
Clone
UC10-4F10-11
Immunogen
Mouse CTLA-4 IgG2a fusion protein
Formulation
PBS buffer, pH 7.0
Isotype
Armenian Hamster IgG
Application
in vivo/vitro CTLA-4 neutralization, FCM,WB
Storage
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Purification
protein A
Sterility
0.2 μM filtered
Properties
Batch:A210306Purity: 99%
Protein concentration:3.3 mg/mlEndotoxin Level:<2 EU/mg
Target
The UC10-4F10-11 monoclonal antibody reacts with mouse CTLA-4 (cytotoxic T lymphocyte antigen-4) also known as CD152. The UC10-4F10-11 antibody has been shown to promote T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding.