[CAS NO. 1016535-83-3] Oct3/4-inducer-1

Name: Oct3/4-inducer-1
Brand: Arctom Scientific
SKU: AS491785

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PRODUCTS SPECIFICATIONS [1016535-83-3]

Distributor

Catalog

AS491785

Brand

Arctom Scientific

CAS

1016535-83-3

DESCRIPTION [1016535-83-3]

Overview

MDL	-
Molecular Weight	241.26
Molecular Formula	C15H12FNO
SMILES	N#CCC1=CC=C(OCC2=CC=C(F)C=C2)C=C1

For research use only. We do not sell to patients.

Summary

Oct3/4-inducer-1 (compound 2) is a potent Oct3/4 inducer. Oct3/4-inducer-1 promotes expression and stabilization of Oct3/4 , and enhances its transcriptional activity in diverse human somatic cells ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 414.49 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.1449 mL	20.7245 mL	41.4491 mL
5 mM	0.8290 mL	4.1449 mL	8.2898 mL
10 mM	0.4145 mL	2.0725 mL	4.1449 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (10.36 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (10.36 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Cheng X, et al. Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers. J Med Chem. 2015;58(12):4976-4983.