[CAS NO. 10191-41-0]  DL-alpha-Tocopherol

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PRODUCTS SPECIFICATIONS [10191-41-0]

Catalog
HY-W020044
Brand
MCE
CAS
10191-41-0

DESCRIPTION [10191-41-0]

Overview

MDLMFCD00006848
Molecular Weight430.71
Molecular FormulaC29H50O2
SMILESCC1=C2C(CCC(CCCC(C)CCCC(C)CCCC(C)C)(C)O2)=C(C)C(O)=C1C

For research use only. We do not sell to patients.


Summary

DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB [1] .


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT00114387 National Institute on Aging (NIA)|Hoffmann-La Roche
Atherosclerosis
July 1996 Phase 2|Phase 3
NCT00235716 US Department of Veterans Affairs|Forest Laboratories|DSM Nutritional Products, Inc.|VA Office of Research and Development
Alzheimer´s Disease
August 2007 Phase 3

Appearance

Liquid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

H 2 O : 100 mg/mL ( 232.17 mM ; Need ultrasonic)

DMSO : 100 mg/mL ( 232.17 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3217 mL 11.6087 mL 23.2175 mL
5 mM 0.4643 mL 2.3217 mL 4.6435 mL
10 mM 0.2322 mL 1.1609 mL 2.3217 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 100 mg/mL (232.17 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (5.80 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (5.80 mM); Suspended solution; Need ultrasonic

  • 4.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.80 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
dl-α-Tocopherol
(±)-α-Tocopherol
Ephanyl
DL-α-Tocopherol
all-rac-α-Tocopherol
Ronotec DF 120
Ronotec 201
Rac-α-Tocopherol
Ronotec 202
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
Uvinul 2000AO
Elementol B
Elementol R
Elementol Basic
Irganox E 210
2,5,7,8-Tetramethyl-2-(4′,8′,12′-trimethyltridecyl)chroman-6-ol
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol
Irganox LE 307