[CAS NO. 1027371-75-0] m-PEG1-NHSester
PRODUCTS SPECIFICATIONS [1027371-75-0]
DESCRIPTION [1027371-75-0]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 201.18 |
| Molecular Formula | C8H11NO5 |
| SMILES | COCCC(ON1C(CCC1=O)=O)=O |
Summary
IC50 & Target
|
PEGs |
Alkyl/ether |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
H 2 O : 33.33 mg/mL ( 165.67 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.9707 mL | 24.8534 mL | 49.7067 mL |
| 5 mM | 0.9941 mL | 4.9707 mL | 9.9413 mL |
| 10 mM | 0.4971 mL | 2.4853 mL | 4.9707 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (497.07 mM); Clear solution; Need ultrasonic
