[CAS NO. 105365-76-2]  RS8359

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PRODUCTS SPECIFICATIONS [105365-76-2]

Distributor
Catalog
AS063047
Brand
Arctom Scientific
CAS
105365-76-2

DESCRIPTION [105365-76-2]

Overview

MDLMFCD00871515
Molecular Weight252.27
Molecular FormulaC14H12N4O
SMILESOC1C2=NC=NC(NC3=CC=C(C#N)C=C3)=C2CC1

For research use only. We do not sell to patients.

Summary

RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity.


In Vivo

RS 8359 shows relatively little effect upon blood pressure when administered together with tyramine. RS-8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 198.20 mM ; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9640 mL 19.8200 mL 39.6401 mL
5 mM 0.7928 mL 3.9640 mL 7.9280 mL
10 mM 0.3964 mL 1.9820 mL 3.9640 mL
* Please refer to the solubility information to select the appropriate solvent.


Synonyms

Benzonitrile, 4-[(6,7-dihydro-7-hydroxy-5H-cyclopentapyrimidin-4-yl)amino]-
5H-Cyclopentapyrimidine, benzonitrile deriv.
4-[(6,7-Dihydro-7-hydroxy-5H-cyclopentapyrimidin-4-yl)amino]benzonitrile
4-(4-Cyanoanilino)-6,7-dihydro-7-hydroxy-5H-cyclopenta[d]pyrimidine
RS 8359