[CAS NO. 107348-47-0] PPC-NHS ester

Name: PPC-NHS ester
Brand: Arctom Scientific
SKU: AS241502

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PRODUCTS SPECIFICATIONS [107348-47-0]

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Catalog

AS241502

Brand

Arctom Scientific

CAS

107348-47-0

For research use only. We do not sell to patients.

PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) ^[1] .

Disulfide Cleavable

Cleavable

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 100 mg/mL ( 306.38 mM ; Need ultrasonic)

Preparing
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Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (7.66 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (7.66 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (7.66 mM); Clear solution

* All of the co-solvents are available by MCE.