[CAS NO. 107767-58-8] A-802715
PRODUCTS SPECIFICATIONS [107767-58-8]
DESCRIPTION [107767-58-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 322.40 |
| Molecular Formula | C16H26N4O3 |
| SMILES | O=C(N1CCCCC(C)(O)C)N(C)C2=C(N(CCC)C=N2)C1=O |
Summary
A802715 is a methylxanthine derivative. A802715 has a TD 50 (toxic dose of 50%) of 0.9-1.1 mM.
In Vitro
The toxicity of the methylxanthine derivative A802715 is determined against the two human melanoma lines, Be11 and MeWo, and against the two human squamous cell carcinoma lines, 4197 and 4451, by vital dye staining assay. A802715 has a TD 50 of 0.9-1.1 mM and is the most toxic. In p53 wt cells BrdU incorporations show that the irradiation-induced suppression of S-phase entry is strongly enhanced by A802715. A802715 prolongs the G 2 /M block or remain ineffective depending on the p53 status of the cell line [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 190 mg/mL ( 589.33 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.1017 mL | 15.5087 mL | 31.0174 mL |
| 5 mM | 0.6203 mL | 3.1017 mL | 6.2035 mL |
| 10 mM | 0.3102 mL | 1.5509 mL | 3.1017 mL |
