[CAS NO. 108466-89-3]  Boc-NH-PEG2-CH2COOH

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PRODUCTS SPECIFICATIONS [108466-89-3]

Distributor
Catalog
AS461103
Brand
Arctom Scientific
CAS
108466-89-3

DESCRIPTION [108466-89-3]

Overview

MDLMFCD17019374
Molecular Weight263.29
Molecular FormulaC11H21NO6
SMILESCC(C)(C)OC(NCCOCCOCC(O)=O)=O

For research use only. We do not sell to patients.

Summary

Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs [1] .


IC50 & Target

PEGs

Alkyl/ether


In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Viscous liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 379.81 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7981 mL 18.9905 mL 37.9809 mL
5 mM 0.7596 mL 3.7981 mL 7.5962 mL
10 mM 0.3798 mL 1.8990 mL 3.7981 mL
* Please refer to the solubility information to select the appropriate solvent.