[CAS NO. 108930-17-2] Protein kinase inhibitor H-7 dihydrochloride
PRODUCTS SPECIFICATIONS [108930-17-2]
DESCRIPTION [108930-17-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 364.29 |
| Molecular Formula | C14H19Cl2N3O2S |
| SMILES | O=S(C1=CC=CC2=C1C=CN=C2)(N3C(C)CNCC3)=O.[H]Cl.[H]Cl |
Summary
Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) [1] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 16.67 mg/mL ( 45.76 mM ; ultrasonic and warming and heat to 80°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.7451 mL | 13.7253 mL | 27.4507 mL |
| 5 mM | 0.5490 mL | 2.7451 mL | 5.4901 mL |
| 10 mM | 0.2745 mL | 1.3725 mL | 2.7451 mL |
Synonyms
