[CAS NO. 1092851-70-1] HemeOxygenase-1-IN-1hydrochloride
PRODUCTS SPECIFICATIONS [1092851-70-1]
DESCRIPTION [1092851-70-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 315.64 |
| Molecular Formula | C13H16BrClN2 |
| SMILES | BrC1=CC=C(CCCCN2C=CN=C2)C=C1.Cl |
4 Publications Citing Use of MCE
Summary
Heme Oxygenase-1-IN-1 (Compound 2) hydrochloride is a heme oxygenase 1 ( HO-1 ) inhibitor with an IC 50 of 0.25 μM [1] .
IC50 & Target
IC 50 : 0.25 μM (HO-1) [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL ( 396.02 mM ; Need ultrasonic)
H 2 O : 100 mg/mL ( 316.82 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.1682 mL | 15.8408 mL | 31.6817 mL |
| 5 mM | 0.6336 mL | 3.1682 mL | 6.3363 mL |
| 10 mM | 0.3168 mL | 1.5841 mL | 3.1682 mL |
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1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (316.82 mM); Clear solution; Need ultrasonic
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2.
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3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (6.59 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.08 mg/mL (6.59 mM); Clear solution
