[CAS NO. 112241-19-7] SMPT

Name: SMPT
Brand: Arctom Scientific
SKU: AS473689

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PRODUCTS SPECIFICATIONS [112241-19-7]

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Catalog

AS473689

Brand

Arctom Scientific

CAS

112241-19-7

MDL	-
Molecular Weight	388.46
Molecular Formula	C18H16N2O4S2
SMILES	O=C(ON1C(CCC1=O)=O)C2=CC=C(C(SSC3=NC=CC=C3)C)C=C2

For research use only. We do not sell to patients.

SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) ^[1] .

Disulfide Cleavable

Non-cleavable

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 200 mg/mL ( 514.85 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 5 mg/mL (12.87 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 5 mg/mL (12.87 mM); Clear solution

* All of the co-solvents are available by MCE.