[CAS NO. 112448-39-2] 3'-Demethylnobiletin

Name: 3'-Demethylnobiletin
Brand: Arctom Scientific
SKU: AS189037

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PRODUCTS SPECIFICATIONS [112448-39-2]

Distributor

Catalog

AS189037

Brand

Arctom Scientific

CAS

112448-39-2

DESCRIPTION [112448-39-2]

Overview

MDL	MFCD21333408
Molecular Weight	388.37
Molecular Formula	C20H20O8
SMILES	O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=C(OC)C(OC)=C(OC)C(OC)=C13

For research use only. We do not sell to patients.

Summary

3'-Demethylnobiletin, a derivative of Nobiletin, is a polymethoxyflavonoid in citrus fruits ^[1] . Nobiletin exhibits anticancer activity and inhibits tumor angiogenesis by regulating Src , FAK , and STAT3 signaling ^[2] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 257.49 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5749 mL	12.8743 mL	25.7486 mL
5 mM	0.5150 mL	2.5749 mL	5.1497 mL
10 mM	0.2575 mL	1.2874 mL	2.5749 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (6.44 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (6.44 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

4H-1-Benzopyran-4-one, 2-(3-hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxy-

2-(3-Hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one

3′-Hydroxy-4′,5,6,7,8-pentamethoxyflavone

3′-Demethylnobiletin

2-(3-Hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one