[CAS NO. 115713-06-9] 6'-O-beta-D-Glucosylgentiopicroside

Name: 6'-O-beta-D-Glucosylgentiopicroside
Brand: Arctom Scientific
SKU: AS901668

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PRODUCTS SPECIFICATIONS [115713-06-9]

Distributor

Catalog

AS901668

Brand

Arctom Scientific

CAS

115713-06-9

DESCRIPTION [115713-06-9]

Overview

MDL	MFCD29049471
Molecular Weight	518.47
Molecular Formula	C22H30O14
SMILES	C=C[C@@H]([C@@H]1O[C@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CO[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)C(C4=CO1)=CCOC4=O

For research use only. We do not sell to patients.

Summary

6'-O-beta-D-Glucosylgentiopicroside is a secoiridoid isolated from the roots of G. straminea . 6'-O-beta-D-Glucosylgentiopicroside strongly suppresses N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 192.88 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9288 mL	9.6438 mL	19.2875 mL
5 mM	0.3858 mL	1.9288 mL	3.8575 mL
10 mM	0.1929 mL	0.9644 mL	1.9288 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (4.82 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (4.82 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (4.82 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Wei S, et al. Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus-induced superoxide generation, phosphorylation and translocation of cytosolic compounds to plasma membrane in human neutrophils. Phytother Res. 2012 Feb;26(2):168-73.

Synonyms

1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-6-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-5,6-dihydro-, (5R,6S)-

1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-6-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-5,6-dihydro-, (5R-trans)-

(5R,6S)-5-Ethenyl-6-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-5,6-dihydro-1H,3H-pyrano[3,4-c]pyran-1-one

6′-O-β-D-Glucosylgentiopicroside

6′-O-β-D-Glucopyranosylgentiopicroside