[CAS NO. 1186372-20-2] TMN355
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PRODUCTS SPECIFICATIONS [1186372-20-2]
Distributor
Catalog
AS894169
Brand
Arctom Scientific
CAS
1186372-20-2
DESCRIPTION [1186372-20-2]
Overview
| MDL | MFCD19440965 |
|---|---|
| Molecular Weight | 380.80 |
| Molecular Formula | C21H14ClFN2O2 |
| SMILES | O=C(NC(NC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C4=C(F)C=CC=C4Cl |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.6261 mL | 13.1303 mL | 26.2605 mL |
| 5 mM | 0.5252 mL | 2.6261 mL | 5.2521 mL |
| 10 mM | 0.2626 mL | 1.3130 mL | 2.6261 mL |
| 50 mM | 0.0525 mL | 0.2626 mL | 0.5252 mL |
Description
TMN355 (Compound 3i) is a potent inhibitor of with IC50 of 1.52 nM and reduces foam cell formation and cytokine secretion. TMN355 is used for the treatment of atherosclerosis.
Targets
| CypA [1] (Cell-free assay) |
| 1.52 nM |
References
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