[CAS NO. 1187451-41-7]  Omidenepag

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PRODUCTS SPECIFICATIONS [1187451-41-7]

Distributor
Catalog
AS949038
Brand
Arctom Scientific
CAS
1187451-41-7

DESCRIPTION [1187451-41-7]

Overview

MDLMFCD30533441
Molecular Weight478.52
Molecular FormulaC23H22N6O4S
SMILESO=C(O)CNC1=NC(CN(CC2=CC=C(N3N=CC=C3)C=C2)S(=O)(C4=CC=CN=C4)=O)=CC=C1

For research use only. We do not sell to patients.

Summary

Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC 50 of 1.1 nM. Omidenepag shows binding affinities (IC 50 ) 10 nM for h-EP2 [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 522.44 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0898 mL 10.4489 mL 20.8978 mL
5 mM 0.4180 mL 2.0898 mL 4.1796 mL
10 mM 0.2090 mL 1.0449 mL 2.0898 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (4.35 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.35 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.35 mM); Clear solution

* All of the co-solvents are available by MCE.