[CAS NO. 1204401-49-9]  WQ 1

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PRODUCTS SPECIFICATIONS [1204401-49-9]

Distributor
Catalog
AS540676
Brand
Arctom Scientific
CAS
1204401-49-9

DESCRIPTION [1204401-49-9]

Overview

MDLMFCD18206882
Molecular Weight337.48
Molecular FormulaC21H23NOS
SMILESO=C1CC(C2CCN(CC3=CC=CC=C3)CC2)SC4=C1C=CC=C4

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.9631 mL14.8157 mL29.6314 mL
5 mM0.5926 mL2.9631 mL5.9263 mL
10 mM0.2963 mL1.4816 mL2.9631 mL
50 mM0.0593 mL0.2963 mL0.5926 mL

Description

WQ 1 is a high affinity and selective antagonist with pKi values of 10.85, 6.53 and 5.80 at σ1, σ2 receptors and dopamine transporter (DAT), displaying σ1/σ2 selectivity ratio of 20893.

Targets

σ1 receptor [1]
(in dopamine transporters assay)
σ2 receptor [1]
(in dopamine transporters assay)
DAT [1]
(in dopamine transporters assay)
10.85(pKi)6.53(pKi)5.8(pKi)