[CAS NO. 1212421-96-9]  (S)-TXNIP-IN-1

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PRODUCTS SPECIFICATIONS [1212421-96-9]

Distributor
Catalog
AS015941
Brand
Arctom Scientific
CAS
1212421-96-9

DESCRIPTION [1212421-96-9]

Overview

MDLMFCD11108870
Molecular Weight248.23
Molecular FormulaC12H12N2O4
SMILESO=C(O)[C@H](C(C)C)N(C1=O)C(C2=C1C=CN=C2)=O

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

(S)-TXNIP-IN-1 is the less active S-enantiomer of TXNIP-IN-1 (HY-115688). TXNIP-IN-1 is a TXNIP-TRX complex inhibitor which can be used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease , or inflammatory disease [1]


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 402.85 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0285 mL 20.1426 mL 40.2852 mL
5 mM 0.8057 mL 4.0285 mL 8.0570 mL
10 mM 0.4029 mL 2.0143 mL 4.0285 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (10.07 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (10.07 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.07 mM); Clear solution

* All of the co-solvents are available by MCE.