[CAS NO. 127634-19-9] BS3Crosslinkerdisodium

Name: BS3Crosslinkerdisodium
Brand: Arctom Scientific
SKU: AS867729

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PRODUCTS SPECIFICATIONS [127634-19-9]

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Catalog

AS867729

Brand

Arctom Scientific

CAS

127634-19-9

MDL	MFCD00054982
Molecular Weight	572.43
Molecular Formula	C16H18N2Na2O14S2
SMILES	O=C(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)CCCCCCC(ON2C(C(S(=O)(O[Na])=O)CC2=O)=O)=O

For research use only. We do not sell to patients.

BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) ^[1] .

Non-cleavable

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Solid

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

In Vitro:

DMSO : 125 mg/mL ( 218.37 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (3.63 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (3.63 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (3.63 mM); Clear solution

* All of the co-solvents are available by MCE.