[CAS NO. 131-12-4]  Pimpinellin

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PRODUCTS SPECIFICATIONS [131-12-4]

Distributor
Catalog
AS904617
Brand
Arctom Scientific
CAS
131-12-4

DESCRIPTION [131-12-4]

Overview

MDLMFCD00597237
Molecular Weight246.22
Molecular FormulaC13H10O5
SMILESO=C(C=C1)OC2=C1C(OC)=C(OC)C3=C2C=CO3

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis [1] .


In Vitro

Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC 50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 406.14 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0614 mL 20.3070 mL 40.6141 mL
5 mM 0.8123 mL 4.0614 mL 8.1228 mL
10 mM 0.4061 mL 2.0307 mL 4.0614 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.15 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

2H-Furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy-
Pimpinellin
5,6-Dimethoxy-2H-furo[2,3-h]-1-benzopyran-2-one
Pimpinelline
Pimpinecilin
6,7-Dimethoxyangelicin
Pimpinelin