[CAS NO. 1310347-50-2] BACE1-IN-1

Name: BACE1-IN-1
Brand: Arctom Scientific
SKU: AS945538

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PRODUCTS SPECIFICATIONS [1310347-50-2]

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Catalog

AS945538

Brand

Arctom Scientific

CAS

1310347-50-2

MDL	MFCD30533310
Molecular Weight	389.33
Molecular Formula	C18H14F3N5O2
SMILES	O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)OCC3(F)F)=C2

For research use only. We do not sell to patients.

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC ₅₀ s of 32 and 47 nM for human BACE1 and BACE2 , respectively.

IC50: 32 nM (human BACE1), 47 nM (human BACE2) ^[1]

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 85 mg/mL ( 218.32 mM ; Need ultrasonic)

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Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.