[CAS NO. 1351758-37-6] RR6
PRODUCTS SPECIFICATIONS [1351758-37-6]
DESCRIPTION [1351758-37-6]
Overview
| MDL | MFCD27664963 |
|---|---|
| Molecular Weight | 293.36 |
| Molecular Formula | C16H23NO4 |
| SMILES | CC(C)(CO)[C@@H](O)C(NCCC(CC1=CC=CC=C1)=O)=O |
2 Publications Citing Use of MCE
Summary
RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC 50 of 540 nM for recombinant vanin-1 . RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC 50 values of 40 nM, 41 nM and 87 nM, respectively [1] .
In Vivo
Oral administration of RR6 in Wistar rats (150-200 g) completely inhibited plasma vanin activity and caused alterations of plasma lipid concentrations upon fasting. RR6 at 3 mg/mL in rats caused a nearly complete inhibition of plasma vanin [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT01267916 | Seoul Medical Center |
General Anesthesia|Laparoscopic Cholecystectomy
|
January 2011 | Not Applicable |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 340.88 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.4088 mL | 17.0439 mL | 34.0878 mL |
| 5 mM | 0.6818 mL | 3.4088 mL | 6.8176 mL |
| 10 mM | 0.3409 mL | 1.7044 mL | 3.4088 mL |
