[CAS NO. 136087-29-1] Isomucronulatol 7-O-glucoside

Name: Isomucronulatol 7-O-glucoside
Brand: Arctom Scientific
SKU: AS124357

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PRODUCTS SPECIFICATIONS [136087-29-1]

Distributor

Catalog

AS124357

Brand

Arctom Scientific

CAS

136087-29-1

DESCRIPTION [136087-29-1]

Overview

MDL	-
Molecular Weight	464.46
Molecular Formula	C23H28O10
SMILES	OC1=C([C@H]2CC3=CC=C(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)C=C3OC2)C=CC(OC)=C1OC

For research use only. We do not sell to patients.

Summary

Isomucronulatol 7-O-glucoside is a flavonoid isolated from the roots of A. membranaceus . Isomucronulatol 7-O-glucoside exhibits weak inhibitory effects on LPS-stimulated production IL-12 p40 in vitro and has potential anti-inflammatory effect ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 215.30 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1530 mL	10.7652 mL	21.5304 mL
5 mM	0.4306 mL	2.1530 mL	4.3061 mL
10 mM	0.2153 mL	1.0765 mL	2.1530 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.38 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.38 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.38 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Li W, et al. Flavonoids from Astragalus membranaceus and their inhibitory effects on LPS-stimulated pro-inflammatory cytokine production in bone marrow-derived dendritic cells. Arch Pharm Res. 2014 Feb;37(2):186-92.