[CAS NO. 1402612-64-9]  KT203

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PRODUCTS SPECIFICATIONS [1402612-64-9]

Distributor
Catalog
AS939239
Brand
Arctom Scientific
CAS
1402612-64-9

DESCRIPTION [1402612-64-9]

Overview

MDLMFCD28118915
Molecular Weight466.53
Molecular FormulaC28H26N4O3
SMILESO=C(N1C(CCCC1)CC2=CC=CC=C2)N3N=NC(C4=CC=C(C=C4)C5=CC=CC(C(O)=O)=C5)=C3

For research use only. We do not sell to patients.

Summary

KT203 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6) , with an IC 50 of 0.31 nM in Neuro2A cells [1] .


IC50 & Target

IC50: 0.31 nM (ABHD6 in Neuro2A cells) [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 214.35 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1435 mL 10.7174 mL 21.4348 mL
5 mM 0.4287 mL 2.1435 mL 4.2870 mL
10 mM 0.2143 mL 1.0717 mL 2.1435 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (5.36 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.36 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

[1,1′-Biphenyl]-3-carboxylic acid, 4′-[1-[[2-(phenylmethyl)-1-piperidinyl]carbonyl]-1H-1,2,3-triazol-4-yl]-
4′-[1-[[2-(Phenylmethyl)-1-piperidinyl]carbonyl]-1H-1,2,3-triazol-4-yl][1,1′-biphenyl]-3-carboxylic acid
KT 203