[CAS NO. 1429180-08-4] MutantIDH1inhibitor
PRODUCTS SPECIFICATIONS [1429180-08-4]
DESCRIPTION [1429180-08-4]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 466.58 |
| Molecular Formula | C25H34N6O3 |
| SMILES | CC(C)[C@@H](COC1=O)N1C2=NC(N[C@@H](C)C3=CC=C(CN4CCN(C(C)=O)CC4)C=C3)=NC=C2 |
1 Publications Citing Use of MCE
Summary
Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC 50 of < 72 nM.
IC50 & Target
IC50: < 72 nM (mutant IDH1 R132H)
In Vitro
Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 34 mg/mL ( 72.87 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.1433 mL | 10.7163 mL | 21.4326 mL |
| 5 mM | 0.4287 mL | 2.1433 mL | 4.2865 mL |
| 10 mM | 0.2143 mL | 1.0716 mL | 2.1433 mL |
