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Catalog: | HY-103159 |
Brand: | MCE |
CAS: | 14432-09-8 |
MDL | - |
---|---|
Molecular Weight | 266.25 |
Molecular Formula | C11H14N4O4 |
SMILES | NC1=C2C(N([C@H]3[C@@H]([C@@H]([C@@H](CO)O3)O)O)C=N2)=NC=C1 |
1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a K i value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders [1] [2] .
1-Deazaadenosine shows good activity in vitro as inhibitor of HeLa, KB, P388, and L1210 leukemia cell line growth, with ID
50
values ranging from 0.34 μM (KB) to 1.8 μM (P388)
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Solid
Room temperature in continental US; may vary elsewhere.
Powder | -20°C | 3 years |
---|---|---|
4°C | 2 years | |
In solvent | -80°C | 6 months |
-20°C | 1 month |
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