[CAS NO. 149-29-1]  Patulin

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PRODUCTS SPECIFICATIONS [149-29-1]

Catelog
HY-N6779
Brand
MCE
CAS
149-29-1

DESCRIPTION [149-29-1]

Overview

MDLMFCD00005858
Molecular Weight154.12
Molecular FormulaC7H6O4
SMILESO=C1OC2=CCOC(C2=C1)O

For research use only. We do not sell to patients.


Summary

Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus , Penicillium , and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage [1] [2] [3] [4] .


Appearance

Solid


Source

Penicillium and Aspergillus


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 648.85 mM ; Need ultrasonic)

H 2 O : 50 mg/mL ( 324.42 mM ; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4885 mL 32.4423 mL 64.8845 mL
5 mM 1.2977 mL 6.4885 mL 12.9769 mL
10 mM 0.6488 mL 3.2442 mL 6.4885 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.5 mg/mL (16.22 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (16.22 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (16.22 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

4H-Furo[3,2-c]pyran-2(6H)-one, 4-hydroxy-
Patulin
4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
Clairformin
Clavacin
Clavatin
Claviformin
Expansin
Expansine
Mycoin
Penicidin
Acetic acid, (2,4-dihydroxy-2H-pyran-3(6H)-ylidene)-, 3,4-lactone
Mycoin C
Patuline
Mycoin C3
Terinin
DL-Patulin
NSC 32951
NSC 8120
Expansin (antibiotic)
Leucopin
Gigantin