[CAS NO. 1492-18-8] Folinicacidcalcium

Name: Folinicacidcalcium
Brand: Arctom Scientific
SKU: AS092894

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PRODUCTS SPECIFICATIONS [1492-18-8]

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Catalog

AS092894

Brand

Arctom Scientific

CAS

1492-18-8

DESCRIPTION [1492-18-8]

Overview

MDL	MFCD08704249
Molecular Weight	511.50
Molecular Formula	C20H21CaN7O7
SMILES	O=C(N[C@H](C([O-])=O)CCC([O-])=O)C(C=C1)=CC=C1NCC(N2C=O)CNC3=C2C(N=C(N)N3)=O.[Ca+2]

For research use only. We do not sell to patients.

3 Publications Citing Use of MCE

Summary

Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity ^[1] .

IC50 & Target

Human Endogenous Metabolite

In Vitro

MTX alone induces a concentration-related increase in % micronucleated binucleated cells (MNBN) and % aberrant cells (Abs). There is a decrease in nuclear division index (NDI) with increase in MTX concentration. Similarly, the mitotic index (MI) also decreases in all concentrations of MTX tested. The addition of Folinic acid at 50 μg/ mL significantly reduces % MNBN (40-68%) and % Abs (36-77%). Inhibition is also seen at 5 μg/ mL Folinic acid (12 to 54% for MNBN and 20 to 61% for Abs) ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Folinic acid (7.0 mg/kg; intraperitoneal injection; every second day; for 3 weeks; Balb/c young growing male mice) treatment following methotrexate (MTX) administration appears to reverse this growth inhibition (Chronic administration of MTX induces suppression of skeletal growth in mice) ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	24 Balb/c young growing male mice aged 3 weeks (11.88 ± 0.25 g) ^[2]
Dosage:	7.0 mg/kg
Administration:	Intraperitoneal injection; every second day; for 3 weeks
Result:	Following methotrexate (MTX) administration appears to reverse this growth inhibition.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT00766142	Institut Bergonié\|Assistance Publique - Hôpitaux de Paris\|Centre Alexis Vautrin, Nancy\|Centre Leon Berard\|Institut Cancerologie de l´Ouest\|Hôpital Haut-Lévêque\|Clinique Francheville, Périgueux	Colorectal Cancer\|Primary Peritoneal Cavity Cancer	May 1, 2007	Phase 2
NCT00932438	University of Louisville\|Biocompatibles UK Ltd	Colon Cancer With Metastases to the Liver	June 2009	Phase 1\|Phase 2
NCT01014767	Tufts Medical Center	Brain Cancer\|Choroid Plexus Tumors	November 2009	Phase 3
NCT00042861	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	August 2002	Phase 1
NCT04430985	Dorte Nielsen\|Danish Cancer Society\|Herlev Hospital	Metastatic Colorectal Cancer	September 30, 2020	Phase 2
NCT02828358	National Cancer Institute (NCI)	Acute Leukemia of Ambiguous Lineage\|B Acute Lymphoblastic Leukemia\|Mixed Phenotype Acute Leukemia	March 27, 2017	Phase 2
NCT00002618	Children´s Oncology Group\|National Cancer Institute (NCI)	Lymphoma	December 1994	Phase 3
NCT01198548	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Stage IV Colon Cancer\|Stage IV Rectal Cancer	August 2010	Phase 2
NCT02256800	Jaw-Yuan Wang, MD, PhD\|Kaohsiung Medical University Chung-Ho Memorial Hospital	Metastatic Colorectal Cancer	August 13, 2014	Not Applicable
NCT01404156	Dr. Gordon Buduhan\|CancerCare Manitoba\|University of Toronto\|London Health Sciences Centre	Esophageal Cancer\|Adenocarcinoma, Esophageal\|Adenocarcinoma, Gastroesophageal Junction	September 2015	Phase 2\|Phase 3
NCT00217737	National Cancer Institute (NCI)	Colon Mucinous Adenocarcinoma\|Colon Signet Ring Cell Adenocarcinoma\|Lynch Syndrome\|Stage IIA Colon Cancer AJCC v7\|Stage IIB Colon Cancer AJCC v7\|Stage IIC Colon Cancer AJCC v7	August 4, 2005	Phase 3
NCT02419495	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Advanced Malignant Solid Neoplasm\|Clinical Stage III Cutaneous Melanoma AJCC v8\|Clinical Stage IV Cutaneous Melanoma AJCC v8\|Fallopian Tube Carcinoma\|Metastatic Lung Non-Small Cell Carcinoma\|Metastatic Malignant Solid Neoplasm\|Metastatic Melanoma\|Metastatic Renal Cell Carcinoma\|Ovarian Carcinoma\|Pathologic Stage III Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8\|Pathologic Stage IIID Cutaneous Melanoma AJCC v8\|Pathologic Stage IV Cutaneous Melanoma AJCC v8\|Primary Peritoneal Carcinoma\|Stage III Lung Cancer AJCC v8\|Stage III Renal Cell Cancer AJCC v8\|Stage IIIA Lung Cancer AJCC v8\|Stage IIIB Lung Cancer AJCC v8\|Stage IIIC Lung Cancer AJCC v8\|Stage IV Lung Cancer AJCC v8\|Stage IV Renal Cell Cancer AJCC v8\|Stage IVA Lung Cancer AJCC v8\|Stage IVB Lung Cancer AJCC v8\|Triple-Negative Breast Carcinoma\|Unresectable Lung Non-Small Cell Carcinoma\|Unresectable Melanoma\|Unresectable Renal Cell Carcinoma	June 26, 2015	Phase 1
NCT00059930	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)\|University of Medicine and Dentistry of New Jersey	Colorectal Cancer\|Metastatic Cancer	January 2003	Phase 1
NCT00006112	Gustave Roussy, Cancer Campus, Grand Paris\|National Cancer Institute (NCI)	Carcinoma of the Appendix\|Colorectal Cancer\|Primary Peritoneal Cavity Cancer	January 1996	Phase 2
NCT00023751	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	July 2001	Phase 2
NCT00112918	Hoffmann-La Roche\|National Cancer Institute (NCI)	Colorectal Cancer	December 2004	Phase 3
NCT00044785	Wellstat Therapeutics	Solid Tumors	August 2002	Phase 1
NCT00077233	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Bristol-Myers Squibb\|Eli Lilly and Company	Colorectal Cancer	December 2003	Phase 3
NCT00006115	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Colorectal Cancer	April 1999	Phase 2
NCT03368859	AbbVie	Cancer	March 20, 2018	Phase 2
NCT05412082	University of Miami	Locally Advanced Rectal Cancer	October 5, 2022	Phase 1
NCT04390399	ImmunityBio, Inc.	Pancreatic Cancer	July 21, 2020	Phase 2
NCT01274624	Oncolytics Biotech\|Montefiore Medical Center	KRAS Mutant Metastatic Colorectal Cancer	December 2010	Phase 1
NCT00098787	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	July 2005	Phase 2
NCT02270606	Virginia Commonwealth University\|National Cancer Institute (NCI)	Mucinous Adenocarcinoma of the Rectum\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Rectum\|Rectal Adenocarcinoma\|Stage IIA Rectal Cancer\|Stage IIB Rectal Cancer\|Stage IIC Rectal Cancer\|Stage IIIA Rectal Cancer\|Stage IIIB Rectal Cancer\|Stage IIIC Rectal Cancer	December 4, 2014	Phase 1
NCT00492999	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	May 2007	Phase 2
NCT05187182	Washington University School of Medicine\|Curis, Inc.	Gastric Cancer\|Esophageal Cancer\|Stomach Cancer\|Esophagus Cancer\|Gastroesophageal Junction Cancer	November 30, 2022	Phase 1
NCT00026273	Pfizer	Colorectal Cancer	January 2001	Phase 3
NCT00064181	European Organisation for Research and Treatment of Cancer - EORTC	Colorectal Cancer	May 2003	Phase 3
NCT00002463	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	February 1989	Phase 2
NCT04546399	National Cancer Institute (NCI)	Down Syndrome\|Recurrent B Acute Lymphoblastic Leukemia	December 4, 2020	Phase 2
NCT01308086	Hellenic Oncology Research Group\|University Hospital of Crete	CRC	October 2010	Phase 3
NCT00003287	European Organisation for Research and Treatment of Cancer - EORTC	Colorectal Cancer	March 1998	Phase 3
NCT00003594	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|NCIC Clinical Trials Group	Colorectal Cancer	October 1998	Phase 3
NCT03169738	ImmunityBio, Inc.	Non-small Cell Lung Cancer	February 2018	Phase 1\|Phase 2
NCT00002665	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Neutropenia\|Thrombocytopenia	July 1995	Phase 2
NCT00019864	National Cancer Institute (NCI)	Cardiac Toxicity\|Sarcoma	March 2000	Phase 2
NCT01535053	GOG Foundation\|National Cancer Institute (NCI)	Choriocarcinoma\|FIGO Stage I Gestational Trophoblastic Tumor\|FIGO Stage II Gestational Trophoblastic Tumor\|FIGO Stage III Gestational Trophoblastic Tumor\|Hydatidiform Mole	June 18, 2012	Phase 3
NCT02270788	St. Jude Children´s Research Hospital\|Arog Pharmaceuticals, Inc.\|Ohio State University	Acute Myeloid Leukemia	April 2, 2015	Phase 1
NCT00111761	Amgen	Colorectal Cancer	July 2002	Phase 2
NCT00005977	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	September 2000	Phase 3
NCT00278889	AstraZeneca	Colorectal Cancer	January 2006	Phase 2
NCT00513266	Centre Hospitalier Universitaire Vaudois\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	June 2007	Phase 2
NCT01246960	Eli Lilly and Company	Stomach Cancer\|Esophageal Cancer	April 2011	Phase 2
NCT00003956	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Lymphoma\|Unspecified Adult Solid Tumor, Protocol Specific	April 1999	Phase 1
NCT02414009	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	Metastatic Colorectal Cancer	September 2014	Phase 2
NCT03414983	Bristol-Myers Squibb\|Ono Pharmaceutical Co. Ltd	Colorectal Cancer	February 20, 2018	Phase 2\|Phase 3
NCT00003799	National Cancer Institute (NCI)	Adenocarcinoma of the Rectum\|Mucinous Adenocarcinoma of the Rectum\|Signet Ring Adenocarcinoma of the Rectum\|Stage IIA Rectal Cancer\|Stage IIB Rectal Cancer\|Stage IIC Rectal Cancer\|Stage IIIA Rectal Cancer\|Stage IIIB Rectal Cancer\|Stage IIIC Rectal Cancer	May 1999	Phase 1
NCT03387085	ImmunityBio, Inc.	Triple Negative Breast Cancer	March 16, 2018	Phase 1\|Phase 2
NCT02415699	Sixth Affiliated Hospital, Sun Yat-sen University	Colorectal Cancer	August 2015	Phase 2\|Phase 3
NCT02436044	Ming Zhao\|Sun Yat-sen University	Hepatocellular Carcinoma\|Injury; Blood Vessel, Hepatic, Artery
NCT00537121	Roswell Park Cancer Institute\|Merck Sharp & Dohme LLC	Esophageal Cancer\|Gastric Cancer\|Liver Cancer	November 2006	Phase 1
NCT01775501	Massachusetts General Hospital	Hepatocellular Cancer	January 2013	Phase 2
NCT00021281	Jonsson Comprehensive Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	December 2000	Phase 3
NCT00098982	European Organisation for Research and Treatment of Cancer - EORTC	Colorectal Cancer	September 2004	Phase 1
NCT05610163	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Locally Advanced Rectal Carcinoma\|Stage II Rectal Cancer AJCC v8\|Stage III Rectal Cancer AJCC v8	November 9, 2022	Phase 2
NCT03559348	National Health Research Institutes, Taiwan\|National Taiwan University Hospital\|China Medical University Hospital\|Kaohsiung Medical University\|Chang Gung Memorial Hospital\|National Cheng-Kung University Hospital	Pancreatic Adenocarcinoma	April 3, 2018	Phase 2
NCT00085163	European Organisation for Research and Treatment of Cancer - EORTC\|Dutch Colorectal Cancer Group (DCCG)\|Arbeitsgemeinschaft fur Internistische Onkologie\|Onkologie\|Egyptian Foundation For Cancer Research\|EORTC GI Group (EORTC 40023)\|Federation Francophone de Cancerologie Digestive\|GCCD-APIO - Grupo Cooperativo do Cancro Digestivo da Associação Portuguesa de Investigação\|Oncológica\|Gruppo Italiano per lo studio dei Carcinomi dell´Apparato Digerente\|GOCCI - Gruppo Oncologico Chirurgico Cooperativo Italiano\|GOIRC - Gruppo Oncologico Italiano di Ricerca Clinica\|SG - Scandinavian Group\|TTD - Grupo Español para el Tratamiento de Tumores Digestivos	Colorectal Cancer	March 2004	Phase 3
NCT03167177	ImmunityBio, Inc.	Melanoma	December 2017	Phase 1\|Phase 2
NCT04882241	Merck Sharp & Dohme LLC	Gastric Cancer\|Gastroesophageal Junction Cancer	July 29, 2020	Phase 3
NCT03428958	NuCana plc	Colorectal Cancer\|Colorectal Neoplasms\|Colorectal Carcinoma\|Colorectal Tumors\|Neoplasms, Colorectal	October 16, 2018	Phase 1\|Phase 2
NCT01588990	Hoffmann-La Roche	Colorectal Neoplasms	June 26, 2012	Phase 4
NCT04927780	Erasmus Medical Center\|Dutch Pancreatic Cancer Group\|Dutch Cancer Society	Pancreatic Cancer\|Pancreatic Ductal Adenocarcinoma\|Resectable Pancreatic Adenocarcinoma	September 7, 2021	Phase 3
NCT00335140	Eastern Cooperative Oncology Group	Lymphoma	December 2006	Phase 2
NCT00006038	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Esophageal Cancer\|Gastric Cancer	February 2000	Phase 2
NCT04097444	Chugai Pharmaceutical	Metastatic Colorectal Cancer	October 11, 2019	Phase 2
NCT00002120	U.S. Bioscience\|Jacobus Pharmaceutical\|NIH AIDS Clinical Trials Information Service	Pneumonia, Pneumocystis Carinii\|HIV Infections		Phase 1
NCT00021398	Fox Chase Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	July 1996	Phase 2
NCT00803647	NSABP Foundation Inc\|Bristol-Myers Squibb	Metastatic Colorectal Cancer	January 2010	Phase 2
NCT00514020	Vanderbilt-Ingram Cancer Center\|National Cancer Institute (NCI)	Gastric Cancer	August 2007	Phase 2
NCT01102686	The Hospital for Sick Children	Gangliosidoses, GM2\|Sandhoff Disease\|Tay-Sachs Disease	August 2009	Phase 1\|Phase 2
NCT00705874	Progen Pharmaceuticals	Cancer	May 2006	Phase 1
NCT00089024	University of Nebraska\|National Cancer Institute (NCI)	Pancreatic Cancer	February 2004	Phase 2
NCT01628211	National Cancer Institute, Naples	Colorectal Cancer	April 2012	Phase 2
NCT03771846	Shi Ming\|Sun Yat-sen University	Intrahepatic Cholangiocarcinoma	August 1, 2018	Phase 3
NCT00952029	Federation Francophone de Cancerologie Digestive	Colorectal Cancer	March 2010	Phase 2\|Phase 3
NCT00004206	University of Leicester\|National Cancer Institute (NCI)	Ovarian Cancer	September 1999	Phase 2
NCT00166465	Mayo Clinic	Locally Advanced Unresectable or Stage IV Colorectal Cancer	August 2003	Phase 1\|Phase 2
NCT01320683	City of Hope Medical Center\|National Cancer Institute (NCI)	Liver Metastases\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	March 2011	Phase 2
NCT00002835	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Lymphoma	October 30, 1995	Phase 3
NCT01183780	Eli Lilly and Company	Colorectal Cancer	December 2, 2010	Phase 3
NCT02912559	National Cancer Institute (NCI)	Colon Adenocarcinoma\|DNA Repair Disorder\|Lynch Syndrome\|Stage III Colon Cancer AJCC v8	September 12, 2017	Phase 3
NCT05296005	Ohio State University Comprehensive Cancer Center	Clinical Stage I Gastric Cancer AJCC v8\|Clinical Stage II Gastric Cancer AJCC v8\|Clinical Stage IIA Gastric Cancer AJCC v8\|Clinical Stage IIB Gastric Cancer AJCC v8\|Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Clinical Stage III Gastric Cancer AJCC v8\|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8\|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Gastric Adenocarcinoma\|Pathologic Stage IB Gastric Cancer AJCC v8\|Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage II Gastric Cancer AJCC v8\|Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIA Gastric Cancer AJCC v8\|Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIB Gastric Cancer AJCC v8\|Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage III Gastric Cancer AJCC v8\|Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIA Gastric Cancer AJCC v8\|Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIB Gastric Cancer AJCC v8\|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIC Gastric Cancer AJCC v8\|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8	May 31, 2022	Phase 1
NCT01858662	Cliniques universitaires Saint-Luc- Université Catholique de Louvain\|Grand Hôpital de Charleroi	Metastatic Colorectal Cancer	January 2014	Phase 2
NCT00941655	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Gastric Cancer	July 22, 2009	Phase 3
NCT02885753	Federation Francophone de Cancerologie Digestive	Colorectal Neoplasms	December 2016	Phase 3
NCT00009737	Hoffmann-La Roche	Colorectal Cancer	November 1998	Phase 3
NCT00098774	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Lymphoma	October 2004	Phase 2
NCT00080990	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	February 2004	Phase 1
NCT04447092	Seoul National University Hospital	Pancreatic Cancer\|Chemotherapy Effect	July 1, 2020	Phase 2
NCT00126256	Gustave Roussy, Cancer Campus, Grand Paris\|Fondation Francaise de Cancerologie Digestive\|Sanofi	Colorectal Cancer\|Metastasis	February 2002	Phase 3
NCT00075595	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Colorectal Cancer	June 2002	Phase 2
NCT00727831	University College, London\|Cancer Research UK	Chemotherapeutic Agent Toxicity\|Lymphoma\|Mucositis\|Neurotoxicity	July 2008	Phase 1\|Phase 2
NCT00550992	Dutch Childhood Oncology Group\|BFM Germany\|CORS Monza Italy\|Associazione Italiana Ematologia Oncologia Pediatrica\|Australian and New Zealand Children´s Oncology Group\|BFM Austria\|CLCG France Belgium Portugal\|COALL Germany\|CPH, Czech republic\|DFCI consortium USA\|FRALLE France\|Hong Kong\|MD Anderson USA\|NOPHO Scandinavian countries\|PINDA, Chile\|PPLLSG Poland\|Seattle USA\|SJCRH USA\|UKCCSG United Kingdom	Leukemia	January 2006	Not Applicable
NCT00003018	Southwest Oncology Group\|National Cancer Institute (NCI)	Pancreatic Cancer	September 1997	Phase 2
NCT00381680	Children´s Oncology Group\|National Cancer Institute (NCI)	B-cell Childhood Acute Lymphoblastic Leukemia\|L1 Childhood Acute Lymphoblastic Leukemia\|L2 Childhood Acute Lymphoblastic Leukemia\|Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia	March 2007	Phase 3
NCT00004102	NYU Langone Health\|National Cancer Institute (NCI)	Colorectal Cancer	January 1999	Phase 2
NCT01871571	University of Southern California\|National Cancer Institute (NCI)	Mucinous Adenocarcinoma of the Rectum\|Signet Ring Adenocarcinoma of the Rectum\|Stage IIA Rectal Cancer\|Stage IIB Rectal Cancer\|Stage IIC Rectal Cancer\|Stage IIIA Rectal Cancer\|Stage IIIB Rectal Cancer\|Stage IIIC Rectal Cancer	August 2, 2013	Phase 2
NCT00069108	Hoffmann-La Roche	Colorectal Cancer	July 2003	Phase 3
NCT02625610	EMD Serono Research & Development Institute, Inc.\|Merck KGaA, Darmstadt, Germany\|EMD Serono	Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction	December 24, 2015	Phase 3
NCT00873093	National Cancer Institute (NCI)	B-cell Adult Acute Lymphoblastic Leukemia\|B-cell Childhood Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Lymphoblastic Lymphoma\|T-cell Adult Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia	March 2009	Phase 2
NCT02574663	TG Therapeutics, Inc.\|SCRI Development Innovations, LLC	Pancreatic Cancer\|Colorectal Cancer\|Rectal Cancer\|Gastric Cancer\|Esophageal Cancer\|Gastrointestinal Stromal Tumor (GIST)	September 11, 2015	Phase 1
NCT00019760	National Institutes of Health Clinical Center (CC)	Recurrent Colon Cancer\|Liver Metastases\|Stage IV Rectal Cancer\|Recurrent Rectal Cancer\|Stage IV Colon Cancer	April 1999	Phase 2
NCT05546411	Kimberly Perez\|Novartis\|Dana-Farber Cancer Institute	Pancreatic Cancer\|Resectable Pancreatic Cancer\|Borderline Resectable Pancreatic Adenocarcinoma\|Pancreatic Adenocarcinoma	March 2023	Phase 2
NCT03500874	Sun Yat-sen University	Colorectal Cancer\|Liver Metastases\|HAI	February 28, 2018	Phase 3
NCT03374254	Merck Sharp & Dohme LLC\|Array BioPharma	Metastatic Colorectal Cancer	February 16, 2018	Phase 1
NCT01013805	Trans Tasman Radiation Oncology Group	Rectal Cancer	November 2009	Phase 2
NCT02997228	National Cancer Institute (NCI)\|NRG Oncology	Metastatic Colorectal Adenocarcinoma\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	November 7, 2017	Phase 3
NCT00016302	National Cancer Institute (NCI)	T-cell Childhood Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia	April 2001	Not Applicable
NCT02810275	Hospital de Clinicas de Porto Alegre\|Universidade Federal de Santa Maria	HIV Infection\|HCV Coinfection	October 2012	Phase 3
NCT00008294	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	August 2000	Phase 1
NCT03505320	Astellas Pharma Global Development, Inc.\|Astellas Pharma Inc	Pharmacokinetics of Zolbetuximab\|Gastric Cancer\|Gastro-esophageal Junction (GEJ) Cancer\|Pharmacokinetics of Oxaliplatin\|Pharmacokinetics of Fluorouracil Bolus (5-FU)	June 29, 2018	Phase 2
NCT02047474	Yale University\|National Cancer Institute (NCI)	Acinar Cell Adenocarcinoma of the Pancreas\|Duct Cell Adenocarcinoma of the Pancreas\|Stage I Pancreatic Cancer\|Stage IIA Pancreatic Cancer\|Stage IIB Pancreatic Cancer	March 25, 2014	Phase 2
NCT00941499	M.D. Anderson Cancer Center	Advanced Cancers	July 2009	Phase 1
NCT03300544	National Cancer Institute (NCI)	Locally Advanced Rectal Adenocarcinoma\|Metastatic Rectal Adenocarcinoma\|Rectal Adenocarcinoma\|Stage III Rectal Cancer AJCC v7\|Stage IIIA Rectal Cancer AJCC v7\|Stage IIIB Rectal Cancer AJCC v7\|Stage IIIC Rectal Cancer AJCC v7\|Stage IV Rectal Cancer AJCC v7\|Stage IVA Rectal Cancer AJCC v7\|Stage IVB Rectal Cancer AJCC v7	September 20, 2017	Phase 1
NCT01862003	University College, London\|Cancer Research UK\|AstraZeneca\|National Institute for Health Research, United Kingdom	Metastatic Colorectal Cancer\|Recurrent Colorectal Cancer	May 2014	Phase 2
NCT00628810	Federation Francophone de Cancerologie Digestive	Colorectal Cancer	January 2007	Phase 2
NCT03684980	Memorial Sloan Kettering Cancer Center\|University of Alabama at Birmingham	Central Nervous System Lymphoma	November 14, 2018	Early Phase 1
NCT00618501	Asan Medical Center\|National Cancer Institute (NCI)	Leukemia	October 2005	Phase 2
NCT00588536	Memorial Sloan Kettering Cancer Center	Langerhans Cell Histiocytosis	January 1995	Phase 2
NCT01418222	Genentech, Inc.\|SCRI Development Innovations, LLC	Colorectal Cancer	September 14, 2011	Phase 2
NCT00321685	National Cancer Institute (NCI)	Rectal Adenocarcinoma\|Stage II Rectal Cancer AJCC v7\|Stage III Rectal Cancer AJCC v7	July 25, 2006	Phase 2
NCT00447967	Hellenic Oncology Research Group\|University Hospital of Crete	Gastric Cancer	July 2004	Phase 2
NCT00000703	National Institute of Allergy and Infectious Diseases (NIAID)	Lymphoma, Non-Hodgkin\|HIV Infections		Not Applicable
NCT00227617	University of California, San Francisco\|Genentech, Inc.\|Sanofi	Gastrointestinal Carcinoid Tumor\|Islet Cell Tumor\|Lung Cancer\|Neoplastic Syndrome\|Neuroendocrine Tumor	June 8, 2005	Phase 2\|Phase 3
NCT00007878	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	September 2000	Phase 1
NCT01228734	Merck KGaA, Darmstadt, Germany	Metastatic Colorectal Cancer	September 9, 2010	Phase 3
NCT00155883	National Taiwan University Hospital	Gastric Cancer	June 2004	Phase 2
NCT03711240	National Cheng-Kung University Hospital	Colorectal Cancer	January 8, 2019	Phase 2
NCT00176774	University of Michigan Rogel Cancer Center	Colorectal Carcinoma	February 2001	Phase 2
NCT00792948	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Adult L1 Acute Lymphoblastic Leukemia\|Adult L2 Acute Lymphoblastic Leukemia\|Adult T Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia	September 1, 2009	Phase 2
NCT00262808	University of Rochester	Colorectal Cancer	March 2004	Phase 2
NCT00002524	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Lymphoma	June 1993	Phase 2
NCT00851045	Bristol-Myers Squibb	Colorectal Cancer (CRC)	October 2009	Phase 2
NCT01270438	National Cancer Institute (NCI)	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	December 2010	Phase 2
NCT00384176	AstraZeneca	Colorectal Cancer	August 30, 2006	Phase 2\|Phase 3
NCT03169777	ImmunityBio, Inc.	Colorectal Cancer	August 2018	Phase 1\|Phase 2
NCT03563144	ImmunityBio, Inc.	Metastatic Pancreatic Cancer	August 2018	Phase 2
NCT00958737	GERCOR - Multidisciplinary Oncology Cooperative Group	Colorectal Cancer	May 12, 2009	Phase 3
NCT01867697	Per Pfeiffer\|Merck Serono International SA\|Odense University Hospital	Metastatic Colorectal Cancer	May 2012	Phase 2
NCT01302613	University of Texas Southwestern Medical Center	Stage II Rectal Cancer\|Stage III Rectal Cancer	March 2011	Phase 1\|Phase 2
NCT03817320	Therapeutic Advances in Childhood Leukemia Consortium\|Takeda\|Children´s Hospital Los Angeles	ALL, Childhood\|Lymphoblastic Lymphoma, Childhood\|Lymphoblastic Leukemia, Acute, Childhood	February 12, 2019	Phase 1\|Phase 2
NCT03703063	Benaroya Research Institute	Pancreatic Adenocarcinoma	September 17, 2018	Phase 1
NCT01835041	Wake Forest University Health Sciences\|National Cancer Institute (NCI)	Acinar Cell Adenocarcinoma of the Pancreas\|Duct Cell Adenocarcinoma of the Pancreas\|Recurrent Pancreatic Cancer\|Stage IV Pancreatic Cancer	April 2013	Phase 1
NCT04615013	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Cervical Esophagus Adenocarcinoma\|Clinical Stage II Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8\|Clinical Stage III Esophageal Adenocarcinoma AJCC v8\|Gastroesophageal Junction Adenocarcinoma\|Pathologic Stage II Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage III Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8\|Thoracic Esophagus Adenocarcinoma	November 23, 2020	Phase 1
NCT00507091	Genzyme, a Sanofi Company\|Sanofi	Metastatic\|Colorectal\|Adenocarcinoma	August 2005	Phase 1
NCT05417386	Colin D. Weekes, M.D.\|Novartis\|Massachusetts General Hospital	Pancreas Cancer\|Metastatic Pancreatic Cancer\|Metastatic Pancreatic Adenocarcinoma	August 9, 2022	Phase 1
NCT00343408	NCIC Clinical Trials Group\|Canadian Cancer Trials Group	Colorectal Cancer\|Lung Cancer	August 8, 2005	Phase 1
NCT00303758	Federation Francophone de Cancerologie Digestive	Pancreatic Cancer	October 2005	Phase 3
NCT01765582	Hoffmann-La Roche	Colorectal Neoplasms	January 23, 2013	Phase 2
NCT00610948	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	March 2008	Phase 1
NCT03142516	Grupo Espanol Multidisciplinario del Cancer Digestivo\|Amgen\|Pivotal S.L.	Colorectal Neoplasms\|Colorectal Carcinoma\|Colorectal Cancer Metastatic\|Neoplasm Metastasis	October 31, 2017	Phase 2
NCT00003925	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	May 1998	Phase 1
NCT00039611	National Cancer Institute (NCI)	Colorectal Cancer	May 2002	Not Applicable
NCT02456844	Bristol-Myers Squibb	Rheumatoid Arthritis	May 2015	Phase 1
NCT00003862	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)	Gastric Cancer	November 1999	Phase 2
NCT03044587	AIO-Studien-gGmbH\|Servier\|Institut für Klinisch-Onkologische Forschung der Krankenhaus Nordwest GmbH	Adenocarcinoma Metastatic\|Biliary Tract Cancer\|Adenocarcinoma of the Biliary Tract\|Adenocarinoma Locally Advanced\|Non-Resectable Hepatocellular Carcinoma\|Intrahepatic Bile Duct Carcinoma\|Extrahepatic Bile Duct Carcinoma	January 24, 2018	Phase 2
NCT03764553	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)\|Servier	Esophageal Cancer	May 1, 2019	Phase 2
NCT00182715	Velindre NHS Trust\|National Cancer Institute (NCI)	Colorectal Cancer	March 2005	Phase 3
NCT05383352	Ipsen	Metastatic Pancreatic Adenocarcinoma	May 30, 2022	Phase 1
NCT00010075	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Breast Cancer	January 2000	Phase 2
NCT02506842	Fudan University	Stage ?A Pancreatic Cancer\|Stage ?B Pancreatic Cancer\|Stage ?A Pancreatic Cancer\|Stage ?B Pancreatic Cancer	June 2015	Phase 3
NCT02515734	Japan Clinical Cancer Research Organization	Colorectal Cancer	August 2015	Phase 2
NCT03279289	Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)\|Sanofi	Metastatic Colorectal Cancer	October 25, 2017	Phase 2
NCT02890355	National Cancer Institute (NCI)	Metastatic Pancreatic Adenocarcinoma\|Recurrent Pancreatic Carcinoma\|Stage IV Pancreatic Cancer AJCC v6 and v7	September 1, 2016	Phase 2
NCT00764907	University Hospital, Motol\|National Cancer Institute (NCI)	Leukemia	November 2002	Phase 3
NCT02022358	University College, London\|Richard Scowcroft Foundation	Osteosarcoma\|Spindle Cell Sarcoma of Bone	July 2007	Phase 2
NCT01815359	Memorial Sloan Kettering Cancer Center\|The Cleveland Clinic\|Brigham and Women´s Hospital\|University of Miami\|University of Pittsburgh Medical Center\|Washington University School of Medicine	Appendix Cancer\|Colorectal Cancer	March 2013	Phase 2
NCT00061945	National Cancer Institute (NCI)	Acute Undifferentiated Leukemia\|B-cell Adult Acute Lymphoblastic Leukemia\|B-cell Childhood Acute Lymphoblastic Leukemia\|L1 Adult Acute Lymphoblastic Leukemia\|L1 Childhood Acute Lymphoblastic Leukemia\|L2 Adult Acute Lymphoblastic Leukemia\|L2 Childhood Acute Lymphoblastic Leukemia\|Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia\|Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia\|Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia\|T-cell Adult Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia	June 2003	Phase 1\|Phase 2
NCT00418938	Amgen	Cancer\|Colon Cancer\|Colorectal Cancer\|Metastatic Cancer\|Rectal Cancer\|Metastatic Colorectal Cancer	November 1, 2006	Phase 2
NCT02539537	UNICANCER	Pancreatic Cancer\|Carcinoma	March 23, 2015	Phase 3
NCT04689347	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	Metastatic Colorectal Cancer	January 1, 2021	Phase 1
NCT00000730	National Institute of Allergy and Infectious Diseases (NIAID)	Pneumonia, Pneumocystis Carinii\|HIV Infections		Phase 3
NCT03611556	MedImmune LLC	Carcinoma\|Metastatic Pancreatic Adenocarcinoma	June 21, 2018	Phase 1\|Phase 2
NCT01941173	City of Hope Medical Center\|National Cancer Institute (NCI)	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	January 2014	Not Applicable
NCT02588105	AstraZeneca\|Syneos Health	Advanced Solid Tumours	November 10, 2015	Phase 1
NCT00058201	Royal Liverpool University Hospital\|NCIC Clinical Trials Group\|Australasian Gastro-Intestinal Trials Group\|National Cancer Institute (NCI)	Pancreatic Cancer	July 2001	Phase 3
NCT00098839	Children´s Oncology Group\|National Cancer Institute (NCI)	Recurrent Childhood Acute Lymphoblastic Leukemia	February 2005	Phase 1\|Phase 2
NCT00037180	Pfizer	Neoplasm Metastasis\|Colorectal Neoplasms	April 2002	Phase 2
NCT00026364	National Cancer Institute (NCI)	Colorectal Cancer	November 2001	Phase 1
NCT03387098	ImmunityBio, Inc.	Pancreatic Cancer	January 2, 2018	Phase 1\|Phase 2
NCT03678428	Sun Yat-sen University	Metastatic Colorectal Cancer\|Liver Metastases	December 31, 2021	Phase 3
NCT02124148	Eli Lilly and Company	Neoplasm Metastasis\|Colorectal Neoplasms\|Breast Cancer	June 18, 2014	Phase 1
NCT04488159	Johannes Laengle, MD, PhD\|Medical University of Vienna	Colon Cancer Stage III	December 1, 2022	Phase 3
NCT01523431	The Affiliated Hospital of the Chinese Academy of Military Medical Sciences	Metastatic Colorectal Cancer	March 8, 2012	Phase 2\|Phase 3
NCT03970252	Jonsson Comprehensive Cancer Center\|Bristol-Myers Squibb\|NovoCure Ltd.	Borderline Resectable Pancreatic Adenocarcinoma\|Resectable Pancreatic Ductal Adenocarcinoma	July 24, 2019	Early Phase 1
NCT05314998	John Neoptolemos\|Molecular Health GmbH\|Deutsches Krebsforschungszentrum (DKFZ)\|Nationales Centrum für Tumorerkrankungen\|Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest\|Institut für Medizinische Biometrie\|Heidelberg University	Pancreatic Ductal Adenocarcinoma	November 1, 2022	Phase 3
NCT00235898	Mast Therapeutics, Inc.	Colon Cancer\|Rectal Cancer	May 2005	Phase 2
NCT01375816	GERCOR - Multidisciplinary Oncology Cooperative Group	Colorectal Cancer	May 2011	Phase 2
NCT00045539	New Approaches to Brain Tumor Therapy Consortium\|National Cancer Institute (NCI)	Lymphoma	October 2002	Phase 2
NCT00000794	National Institute of Allergy and Infectious Diseases (NIAID)	Toxoplasmosis, Cerebral\|HIV Infections		Phase 2
NCT00006103	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	July 2000	Phase 3
NCT00525785	M.D. Anderson Cancer Center\|Sanofi-Synthelabo	Stomach Cancer\|Gastric Cancer	January 2004	Phase 2
NCT00000724	National Institute of Allergy and Infectious Diseases (NIAID)	Pneumonia, Pneumocystis Carinii\|HIV Infections		Phase 3
NCT00577109	Hoffmann-La Roche\|Merck KGaA, Darmstadt, Germany	Colorectal Cancer	December 2007	Phase 2
NCT00004164	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Head and Neck Cancer	August 1999	Phase 2
NCT00303771	Federation Francophone de Cancerologie Digestive	Colorectal Cancer	June 2003	Phase 3
NCT00165178	Dana-Farber Cancer Institute\|Boston Children´s Hospital\|University of Rochester\|McMaster University\|San Jorge Children´s Hospital (Puerto Rico)\|St. Justine´s Hospital\|Maine Children´s Cancer Program\|Ochsner Health System\|Tulane University School of Medicine\|Laval University\|Columbia University	Acute Lymphoblastic Leukemia	September 2000	Phase 3
NCT00004233	Southwest Oncology Group\|National Cancer Institute (NCI)	Esophageal Cancer\|Gastric Cancer	February 2001	Phase 2
NCT00002700	European Organisation for Research and Treatment of Cancer - EORTC\|Acute Leukemia French Association	Leukemia\|Lymphoma	August 1995	Phase 3
NCT03554109	ImmunityBio, Inc.	Triple Negative Breast Cancer (TNBC)	September 2018	Phase 2
NCT00663481	Mast Therapeutics, Inc.	Healthy Adults	April 2008	Phase 1
NCT01307956	University of Nebraska\|National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Esophageal Adenocarcinoma\|Stage IIA Esophageal Cancer\|Stage IIB Esophageal Cancer	February 2011	Phase 2
NCT00080951	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	March 2004	Phase 2
NCT00004228	Children´s Oncology Group\|National Cancer Institute (NCI)	Lymphoma	June 2000	Phase 3
NCT01256398	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1	December 14, 2010	Phase 2
NCT05251038	Devalingam Mahalingam\|Amgen\|Hoosier Cancer Research Network	Pancreatic Cancer\|Unresectable Pancreatic Cancer\|Metastatic Pancreatic Cancer\|KRAS P.G12C	September 13, 2022	Phase 1\|Phase 2
NCT03203525	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Advanced Malignant Neoplasm\|Colorectal Carcinoma Metastatic in the Liver\|Metastatic Malignant Neoplasm in the Liver\|Refractory Malignant Neoplasm	June 23, 2020	Phase 1
NCT00632268	National Taiwan University Hospital\|National Cheng-Kung University Hospital\|Taipei Veterans General Hospital, Taiwan	Metastatic Gastric Cancer	February 2008	Phase 2
NCT03736720	Roswell Park Cancer Institute\|Ipsen	Locally Advanced Digestive System Neuroendocrine Carcinoma\|Locally Advanced Pancreatic Neuroendocrine Carcinoma\|Metastatic Digestive System Neuroendocrine Carcinoma\|Metastatic Pancreatic Neuroendocrine Carcinoma\|Refractory Digestive System Neuroendocrine Carcinoma\|Refractory Pancreatic Neuroendocrine Carcinoma\|Unresectable Digestive System Neuroendocrine Carcinoma\|Unresectable Pancreatic Neuroendocrine Carcinoma	June 17, 2019	Phase 2
NCT00720109	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1	July 14, 2008	Phase 2\|Phase 3
NCT00003700	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia	January 1999	Phase 2
NCT00070122	National Cancer Institute (NCI)	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage III Colon Cancer\|Stage III Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	April 2004	Phase 3
NCT04662710	Merck Sharp & Dohme LLC\|Eisai Inc.	Advanced+Metastatic Gastroesophageal Adenocarcinoma	December 30, 2020	Phase 3
NCT02101853	National Cancer Institute (NCI)	Recurrent B Acute Lymphoblastic Leukemia	December 8, 2014	Phase 3
NCT00308516	SCRI Development Innovations, LLC\|Genentech, Inc.	Rectal Cancer\|Cancer of the Rectum\|Colorectal Cancer	March 2006	Phase 2
NCT00005036	National Cancer Institute (NCI)\|Southwest Oncology Group\|Eastern Cooperative Oncology Group	Mucinous Adenocarcinoma of the Colon\|Mucinous Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Colon\|Signet Ring Adenocarcinoma of the Rectum\|Stage IIIA Colon Cancer\|Stage IIIA Rectal Cancer\|Stage IIIB Colon Cancer\|Stage IIIB Rectal Cancer\|Stage IIIC Colon Cancer\|Stage IIIC Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	November 1999	Phase 3
NCT02856867	European Organisation for Research and Treatment of Cancer - EORTC	Esophagogastric Adenocarcinoma\|Metastatic Disease\|No Previous Chemotherapy for Metastatic Esophagogastric Cancer	December 2016	Phase 2
NCT00004317	National Institute of Allergy and Infectious Diseases (NIAID)\|University of Chicago\|Office of Rare Diseases (ORD)	Toxoplasmosis	July 2000	Phase 4
NCT01190930	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Lymphoblastic Lymphoma\|Ann Arbor Stage I B Lymphoblastic Lymphoma\|Ann Arbor Stage II B Lymphoblastic Lymphoma\|Childhood B Acute Lymphoblastic Leukemia\|Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Childhood B Lymphoblastic Lymphoma\|Down Syndrome\|Hypodiploid B Acute Lymphoblastic Leukemia\|Philadelphia Chromosome Positive	August 9, 2010	Phase 3
NCT05445440	Bristol-Myers Squibb	Healthy Participants	September 6, 2022	Phase 1
NCT04937738	Ukrainian Society of Clinical Oncology	Gastric Cancer	July 21, 2021	Phase 2
NCT03929666	Zymeworks Inc.	HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer	August 29, 2019	Phase 2
NCT01700569	Institut Cancerologie de l´Ouest\|Centre Antoine Lacassagne\|Hospices Civils de Lyon	Grade IV Astrocytoma\|Glioblastoma	January 2013	Phase 1
NCT02099175	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano\|Regione Lombardia	Sinonasal Tumors	November 2013	Phase 2
NCT05489211	AstraZeneca\|Daiichi Sankyo, Inc.	Endometrial Cancer\|Gastric Cancer\|Metastatic Castration-resistant Prostate Cancer\|Ovarian Cancer\|Colorectal Cancer	September 6, 2022	Phase 2
NCT00423696	UNICANCER	Colorectal Cancer	March 23, 2006	Phase 2
NCT00884767	Institut Cancerologie de l´Ouest\|National Cancer Institute (NCI)	Chemotherapeutic Agent Toxicity\|Colorectal Cancer\|Neurotoxicity	September 2007	Phase 2
NCT03197584	ImmunityBio, Inc.	Ovarian Cancer	December 2017	Phase 1\|Phase 2
NCT00267865	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	AIDS-Related-Primary Central Nervous System Lymphoma	September 14, 2006	Phase 2
NCT01666730	Case Comprehensive Cancer Center	Acinar Cell Adenocarcinoma of the Pancreas\|Duct Cell Adenocarcinoma of the Pancreas\|Recurrent Pancreatic Cancer\|Stage IV Pancreatic Cancer	February 21, 2013	Phase 2
NCT00002476	Cancer Research UK\|National Cancer Institute (NCI)	Head and Neck Cancer	January 1990	Phase 3
NCT01506167	Hoffmann-La Roche	Colorectal Cancer	July 6, 2012
NCT00119301	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Sarcoma	April 2005	Phase 1
NCT00103103	California Cancer Consortium\|National Cancer Institute (NCI)	Gastric Cancer	March 2005	Phase 2
NCT00002434	U.S. Bioscience\|NIH AIDS Clinical Trials Information Service	Pneumonia, Pneumocystis Carinii\|HIV Infections		Not Applicable
NCT03281369	Hoffmann-La Roche\|Halozyme Therapeutics\|BioLineRx, Ltd.	Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma	October 13, 2017	Phase 1\|Phase 2
NCT02676323	St. Jude Children´s Research Hospital	Acute Myeloid Leukemia\|Myelodysplastic Syndrome	May 3, 2016	Phase 1
NCT04447352	Krankenhaus Nordwest\|Deutsche Krebshilfe e.V., Bonn (Germany)	Gastric Cancer\|Gastroesophageal Junction Adenocarcinoma	December 17, 2020	Phase 3
NCT00039377	National Cancer Institute (NCI)	Adult Acute Lymphoblastic Leukemia in Remission	April 2002	Phase 2
NCT00982592	National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Adenocarcinoma of the Stomach\|Recurrent Gastric Cancer\|Stage IIIA Gastric Cancer\|Stage IIIB Gastric Cancer\|Stage IIIC Gastric Cancer\|Stage IV Gastric Cancer	September 2009	Phase 2
NCT00296608	Federation Francophone de Cancerologie Digestive	Colorectal Cancer	April 1993	Phase 3
NCT02735239	Ludwig Institute for Cancer Research\|AstraZeneca	Esophageal Cancer	June 24, 2016	Phase 1\|Phase 2
NCT00070434	Southwest Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	August 2004	Phase 2
NCT03136406	ImmunityBio, Inc.	Pancreatic Cancer	August 14, 2017	Phase 1\|Phase 2
NCT02345746	Western Regional Medical Center	Metastatic Colorectal Cancer	December 2012	Phase 2
NCT03522649	1Globe Health Institute LLC\|1Globe Biomedical Co., Ltd.	Previously Treated Metastatic Colorectal Cancer	April 12, 2018	Phase 3
NCT00004150	Robert Roessle Klinik\|European Organisation for Research and Treatment of Cancer - EORTC\|Federation Francophone de Cancerologie Digestive\|Grupo Espanol Tratamiento Tumores Digestivos\|National Cancer Institute (NCI)	Colorectal Cancer	March 1999	Phase 3
NCT00002704	National Cancer Institute (NCI)	Leukemia	January 1996	Phase 2
NCT00448760	University of Miami	Esophageal Cancer	October 2004	Phase 2
NCT00003331	NYU Langone Health\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Precancerous Condition\|Unspecified Adult Solid Tumor, Protocol Specific	January 1998	Phase 1
NCT00139243	Dana-Farber Cancer Institute\|Sanofi\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center	Squamous Cell Carcinoma\|Carcinoma of Head and+or Neck	October 1997	Phase 1\|Phase 2
NCT00079274	National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Adenocarcinoma of the Colon\|Stage III Colon Cancer	February 2004	Phase 3
NCT00155558	National Taiwan University Hospital	Recurrent or Metastatic Colorectal Cancer	March 2001	Phase 1
NCT00378716	NSABP Foundation Inc\|National Cancer Institute (NCI)	Colorectal Cancer	February 1997	Phase 3
NCT01633970	Genentech, Inc.	Cancer	July 11, 2012	Phase 1
NCT00905047	Centre Oscar Lambret	Colorectal Cancer	September 2005	Phase 3
NCT01279681	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Cancer and Leukemia Group B	Cognitive+Functional Effects\|Colorectal Cancer\|Neurotoxicity	January 2011	Phase 3
NCT00100841	National Cancer Institute (NCI)	Adenocarcinoma of the Rectum\|Mucinous Adenocarcinoma of the Colon\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Colon\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	November 2004	Phase 2
NCT00062426	Prologue Research International\|National Cancer Institute (NCI)	Colorectal Cancer	May 2003	Phase 3
NCT01230983	Children´s Oncology Group\|National Cancer Institute (NCI)	Cardiac Toxicity\|Leukemia\|Lymphoma	June 1996	Phase 3
NCT00020943	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Lymphoma	June 2001	Phase 2
NCT00016133	Intracel\|National Cancer Institute (NCI)	Colorectal Cancer	March 2001	Phase 1\|Phase 2
NCT02959541	Vastra Gotaland Region	Colon Cancer\|Chemotherapy	September 2016	Not Applicable
NCT01383343	National Cancer Institute (NCI)	Recurrent Colon Carcinoma\|Recurrent Rectal Carcinoma\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	August 2011	Phase 1
NCT00003835	National Cancer Institute (NCI)\|Southwest Oncology Group\|North Central Cancer Treatment Group\|Eastern Cooperative Oncology Group\|NCIC Clinical Trials Group	Adenocarcinoma of the Colon\|Stage III Colon Cancer	May 1999	Phase 3
NCT03563170	ImmunityBio, Inc.	Hepatocellular Carcinoma Non-resectable\|Hepatocellular Carcinoma Recurrent	May 25, 2018	Phase 1\|Phase 2
NCT00039130	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	May 2002	Phase 2
NCT03837977	The Christie NHS Foundation Trust\|University of Leeds\|Servier\|National Institute for Health Research, United Kingdom	Oncology\|Neuroendocrine Carcinoma	November 13, 2018	Phase 2
NCT00252564	US Oncology Research\|Bristol-Myers Squibb\|Memorial Sloan Kettering Cancer Center\|Prologue Research International	Metastatic Colorectal Cancer	September 2005	Phase 3
NCT01442649	UNICANCER	Colorectal Cancer	December 2010	Phase 2
NCT01077739	Hoffmann-La Roche	Colorectal Cancer	July 2009	Phase 2
NCT00335816	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	August 2008	Phase 2
NCT00020501	National Institutes of Health Clinical Center (CC)\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	March 2001	Phase 3
NCT00041132	Southwest Oncology Group\|National Cancer Institute (NCI)	Lymphoma	September 2002	Phase 2
NCT00309517	Austrian Breast & Colorectal Cancer Study Group	Rectal Cancer Dukes B, Dukes C	July 1997	Phase 3
NCT01258634	University of Chicago	Osteosarcoma\|Lung Metastases	July 2010	Phase 1
NCT01494363	Soon Chun Hyang University	Biliary Tract Cancer	October 2011	Phase 2
NCT00001013	National Institute of Allergy and Infectious Diseases (NIAID)	Pneumonia, Pneumocystis Carinii\|HIV Infections		Phase 3
NCT01238965	University of Southern California\|Novartis	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	October 2010	Phase 1
NCT00143403	Pfizer	Colorectal Neoplasms\|Liver Neoplasms	December 2001	Phase 3
NCT02921256	National Cancer Institute (NCI)\|NRG Oncology	Rectal Adenocarcinoma\|Stage II Rectal Cancer AJCC v7\|Stage III Rectal Cancer AJCC v7	October 12, 2016	Phase 2
NCT01442935	UNICANCER	Colorectal Cancer	February 2011	Phase 2
NCT03193190	Hoffmann-La Roche	Pancreatic Adenocarcinoma	July 5, 2017	Phase 1\|Phase 2
NCT05018182	West China Hospital	High-risk Locally Advanced Colorectal Cancer\|Neoadjuvant Chemotherapy\|FOLFOXIRI Regimen	August 2, 2021	Phase 2
NCT00002590	Children´s Oncology Group\|National Cancer Institute (NCI)	Lymphoma	July 1994	Phase 2
NCT00136435	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Queen Elizabeth II Health Sciences Centre	Acute Lymphoblastic Leukemia	June 2002	Phase 2
NCT02934529	Ludwig-Maximilians - University of Munich	Metastatic Colorectal Cancer	March 2015	Phase 3
NCT00449137	University of Miami	Colorectal Cancer	June 2005	Phase 1
NCT00006479	European Organisation for Research and Treatment of Cancer - EORTC\|Australasian Gastro-Intestinal Trials Group\|Arbeitsgruppe Lebermetastasen und Tumoren\|Cancer Research UK\|Fondation Francaise de Cancerologie Digestive\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	September 2000	Phase 3
NCT05330429	Gilead Sciences	Metastatic Colorectal Cancer	July 8, 2022	Phase 2
NCT03131973	Bristol-Myers Squibb	Rheumatoid Arthritis	May 13, 2017	Phase 1
NCT00515216	Vanderbilt University\|University of Alabama at Birmingham\|University of North Carolina\|Washington University School of Medicine\|National Cancer Institute (NCI)	Stomach Neoplasms\|Esophageal Neoplasms	August 2007	Phase 2
NCT02041481	City of Hope Medical Center\|National Cancer Institute (NCI)\|Array BioPharma	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	June 2014	Phase 1
NCT02987699	Sun Yat-sen University	HepatoCellular Carcinoma	November 2016	Phase 2
NCT00090025	Helsinn Healthcare SA	Biliary Tract Cancer	September 2004	Phase 3
NCT04329494	City of Hope Medical Center\|National Cancer Institute (NCI)	Clinical Stage IV Gastric Cancer AJCC v8\|Clinical Stage IVA Gastric Cancer AJCC v8\|Clinical Stage IVB Gastric Cancer AJCC v8\|Malignant Uterine Neoplasm\|Metastatic Appendix Carcinoma\|Metastatic Colorectal Carcinoma\|Metastatic Gastric Carcinoma\|Metastatic Malignant Neoplasm in the Peritoneum\|Metastatic Malignant Solid Neoplasm\|Metastatic Ovarian Carcinoma\|Pathologic Stage IV Gastric Cancer AJCC v8\|Peritoneal Carcinomatosis\|Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8\|Stage IV Appendix Carcinoma AJCC v8\|Stage IV Colorectal Cancer AJCC v8\|Stage IV Ovarian Cancer AJCC v8\|Stage IV Uterine Corpus Cancer AJCC v8\|Stage IVA Appendix Carcinoma AJCC v8\|Stage IVA Colorectal Cancer AJCC v8\|Stage IVA Ovarian Cancer AJCC v8\|Stage IVA Uterine Corpus Cancer AJCC v8\|Stage IVB Appendix Carcinoma AJCC v8\|Stage IVB Colorectal Cancer AJCC v8\|Stage IVB Ovarian Cancer AJCC v8\|Stage IVB Uterine Corpus Cancer AJCC v8\|Stage IVC Appendix Carcinoma AJCC v8\|Stage IVC Colorectal Cancer AJCC v8	August 21, 2020	Phase 1
NCT00002471	Memorial Sloan Kettering Cancer Center	Leukemia\|Lymphoma	February 1990	Phase 2
NCT04562558	xiang yang\|Peking Union Medical College Hospital	Gestational Trophoblastic Tumor\|Gestational Trophoblastic Neoplasia\|Stage I Gestational Trophoblastic Tumor\|Stage II Gestational Trophoblastic Tumor\|Stage III Gestational Trophoblastic Tumor\|Invasive Mole\|Choriocarcinoma	September 29, 2020	Not Applicable
NCT04072198	Gruppo Oncologico Italiano di Ricerca Clinica	Colorectal Cancer	September 26, 2019	Phase 2
NCT00003446	Grupo Oncologico Cooperativo del Sur\|National Cancer Institute (NCI)	Colorectal Cancer	December 1997	Phase 2
NCT04233866	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Metastatic Pancreatic Adenocarcinoma\|Stage IV Pancreatic Cancer AJCC v8	June 18, 2020	Phase 2
NCT00000658	National Institute of Allergy and Infectious Diseases (NIAID)\|Schering-Plough	Lymphoma, Non-Hodgkin\|HIV Infections		Phase 3
NCT02730546	Mayo Clinic\|National Cancer Institute (NCI)	Gastric Cardia Adenocarcinoma\|Gastroesophageal Junction Adenocarcinoma\|Stage IB Gastric Cancer AJCC v7\|Stage II Gastric Cancer AJCC v7\|Stage IIA Gastric Cancer AJCC v7\|Stage IIB Gastric Cancer AJCC v7\|Stage IIIA Gastric Cancer AJCC v7\|Stage IIIB Gastric Cancer AJCC v7	June 24, 2016	Phase 1\|Phase 2
NCT03043547	AIO-Studien-gGmbH\|Servier	Cholangiocarcinoma Non-resectable\|Cholangiocarcinoma Metastatic\|Cholangiocarcinoma of the Gallbladder\|Cholangiocarcinoma Advanced	October 24, 2017	Phase 2
NCT00004931	National Cancer Institute (NCI)	Stage II Colon Cancer\|Stage III Colon Cancer	February 2000	Phase 3
NCT01924819	Australasian Gastro-Intestinal Trials Group\|National Health and Medical Research Council, Australia\|Trans Tasman Radiation Oncology Group\|European Organisation for Research and Treatment of Cancer - EORTC\|NCIC Clinical Trials Group	Gastric Cancer	September 2009	Phase 2\|Phase 3
NCT03169764	ImmunityBio, Inc.	Head and Neck Squamous Cell Carcinoma	December 2017	Phase 1\|Phase 2
NCT03009058	Immodulon Therapeutics Ltd	Metastatic Cancer	May 24, 2017	Phase 1\|Phase 2
NCT00467142	Institut Bergonié	Colorectal Cancer	January 23, 2007	Phase 2
NCT01467115	Drexel University College of Medicine\|Drexel University	Head and Neck Cancer	March 2010	Phase 2
NCT00149578	National Health Research Institutes, Taiwan\|Chang Gung Memorial Hospital\|National Taiwan University Hospital\|Mackay Memorial Hospital\|China Medical University Hospital\|National Cheng-Kung University Hospital	Pancreatic Cancer	October 2004	Phase 2
NCT01399684	Genentech, Inc.	Metastatic Colorectal Cancer	November 2011	Phase 2
NCT03778593	Dong-A University Hospital	Biliary Tract Cancer	March 1, 2019	Phase 2
NCT02839915	Rossignol Medical Center\|Emory University\|Harvard University\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)\|State University of New York - Downstate Medical Center\|Southwest Autism Research & Resource Center	Autism Spectrum Disorder	August 13, 2020	Phase 2
NCT00002557	National Cancer Institute (NCI)	Lymphoma	June 1993	Phase 2
NCT02138617	UNC Lineberger Comprehensive Cancer Center	Colon Cancer	May 2014	Phase 2
NCT00275106	Children´s Cancer and Leukaemia Group\|European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma\|National Cancer Institute (NCI)	Lymphoma	September 2004	Phase 3
NCT03443492	National Health Research Institutes, Taiwan\|National Taiwan University Hospital\|Taipei Veterans General Hospital, Taiwan\|China Medical University Hospital\|National Cheng-Kung University Hospital\|Kaohsiung Medical University\|Taipei Medical University Shuang Ho Hospital\|Chang Gung Memorial Hospital\|Tri-Service General Hospital\|E-DA Hospital	Locally Advanced or Metastatic Pancreatic Cancer	March 26, 2018	Phase 2
NCT00673179	M.D. Anderson Cancer Center	Osteosarcoma	May 2008	Not Applicable
NCT03067792	Yonsei University	Inoperable Gastric Cancer	December 2014	Phase 3
NCT01897454	Albert Einstein College of Medicine\|National Cancer Institute (NCI)	Pancreatic Adenocarcinoma\|Stage IIA Pancreatic Cancer\|Stage IIB Pancreatic Cancer\|Stage III Pancreatic Cancer	November 2012	Phase 2
NCT02231723	Sumitomo Pharma Oncology, Inc.	Metastatic Pancreatic Adenocarcinoma	August 2014	Phase 1
NCT04210115	Merck Sharp & Dohme LLC	Esophageal Squamous Cell Carcinoma (ESCC)\|Gastroesophageal Junction Carcinoma (GEJC)\|Esophageal Adenocarcinoma (EAC)	February 28, 2020	Phase 3
NCT00262925	National Cancer Institute (NCI)	Recurrent Adult Acute Lymphoblastic Leukemia	June 2006	Phase 2
NCT00027833	Herbert Irving Comprehensive Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	December 2001	Phase 2
NCT04703101	Jonsson Comprehensive Cancer Center	Locally Advanced Rectal Carcinoma\|Rectal Adenocarcinoma\|Stage II Rectal Cancer AJCC v8\|Stage IIA Rectal Cancer AJCC v8\|Stage IIB Rectal Cancer AJCC v8\|Stage IIC Rectal Cancer AJCC v8\|Stage III Rectal Cancer AJCC v8\|Stage IIIA Rectal Cancer AJCC v8\|Stage IIIB Rectal Cancer AJCC v8\|Stage IIIC Rectal Cancer AJCC v8	February 11, 2021	Phase 1
NCT00021073	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	May 2001	Phase 1
NCT05032183	M.D. Anderson Cancer Center	Recurrent Adult Lymphoblastic Lymphoma\|Recurrent B Acute Lymphoblastic Leukemia\|Recurrent T Acute Lymphoblastic Leukemia\|Refractory B Acute Lymphoblastic Leukemia\|Refractory Lymphoblastic Lymphoma\|Refractory T Acute Lymphoblastic Leukemia	February 17, 2022	Phase 1\|Phase 2
NCT00425152	NSABP Foundation Inc\|National Cancer Institute (NCI)\|Northern California Cancer Center	Colorectal Cancer	July 1989	Phase 3
NCT00003834	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	March 1999	Phase 2
NCT00469443	Hellenic Oncology Research Group\|University Hospital of Crete	Colorectal Cancer	December 2006	Phase 3
NCT01768182	Hospital de Clinicas de Porto Alegre\|Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.	Human Immunodeficiency Virus (HIV) Infection	August 2009	Not Applicable
NCT04481204	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Borderline Resectable Pancreatic Adenocarcinoma\|Locally Advanced Pancreatic Ductal Adenocarcinoma\|Resectable Pancreatic Ductal Adenocarcinoma	November 30, 2022	Phase 2
NCT04761614	Ning Jin\|Ohio State University Comprehensive Cancer Center	Metastatic Colorectal Carcinoma\|Stage IV Colorectal Cancer AJCC v8\|Stage IVA Colorectal Cancer AJCC v8\|Stage IVB Colorectal Cancer AJCC v8\|Stage IVC Colorectal Cancer AJCC v8	April 2, 2021	Phase 1
NCT00002896	European Institute of Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	September 1993	Phase 3
NCT00559676	Centre Hospital Regional Universitaire de Limoges\|National Cancer Institute (NCI)	Colorectal Cancer	March 2005	Phase 4
NCT00513981	Children´s Cancer and Leukaemia Group\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors\|Sarcoma\|Unspecified Childhood Solid Tumor, Protocol Specific	March 2007	Phase 1
NCT00019513	National Institutes of Health Clinical Center (CC)\|National Cancer Institute (NCI)	Colorectal Cancer\|Esophageal Cancer\|Extrahepatic Bile Duct Cancer\|Gallbladder Cancer\|Liver Cancer\|Lung Cancer\|Lymphoma\|Pancreatic Cancer\|Small Intestine Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	August 1998	Phase 1
NCT00433927	PD Dr. med. Volker Heinemann\|Merck KGaA, Darmstadt, Germany\|Ludwig-Maximilians - University of Munich	Neoplasm Metastasis\|Colorectal Cancer	January 2007	Phase 3
NCT04535401	National Cancer Institute (NCI)	Advanced Colorectal Carcinoma\|Advanced Digestive System Carcinoma\|Advanced Gastric Carcinoma\|Advanced Gastroesophageal Junction Adenocarcinoma\|Clinical Stage III Gastric Cancer AJCC v8\|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8\|Clinical Stage IV Gastric Cancer AJCC v8\|Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8\|Clinical Stage IVA Gastric Cancer AJCC v8\|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Clinical Stage IVB Gastric Cancer AJCC v8\|Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Metastatic Colorectal Carcinoma\|Metastatic Digestive System Carcinoma\|Metastatic Gastric Carcinoma\|Metastatic Gastroesophageal Junction Adenocarcinoma\|Pathologic Stage III Gastric Cancer AJCC v8\|Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIA Gastric Cancer AJCC v8\|Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIB Gastric Cancer AJCC v8\|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIC Gastric Cancer AJCC v8\|Pathologic Stage IV Gastric Cancer AJCC v8\|Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Postneoadjuvant Therapy Stage III Gastric Cancer AJCC v8\|Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8\|Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Postneoadjuvant Therapy Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8\|Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8\|Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Stage III Colorectal Cancer AJCC v8\|Stage IIIA Colorectal Cancer AJCC v8\|Stage IIIB Colorectal Cancer AJCC v8\|Stage IIIC Colorectal Cancer AJCC v8\|Stage IV Colorectal Cancer AJCC v8\|Stage IVA Colorectal Cancer AJCC v8\|Stage IVB Colorectal Cancer AJCC v8\|Stage IVC Colorectal Cancer AJCC v8	March 15, 2021	Phase 1
NCT00544349	Gustave Roussy, Cancer Campus, Grand Paris\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	October 2006	Phase 2
NCT01121848	Sanofi	Pancreatic Neoplasms	July 2010	Phase 3
NCT01212822	Fox Chase Cancer Center\|National Cancer Institute (NCI)	Adenocarcinoma of the Esophagus\|Adenocarcinoma of the Gastroesophageal Junction\|Diffuse Adenocarcinoma of the Stomach\|Intestinal Adenocarcinoma of the Stomach\|Mixed Adenocarcinoma of the Stomach\|Squamous Cell Carcinoma of the Esophagus\|Stage IA Esophageal Cancer\|Stage IA Gastric Cancer\|Stage IB Esophageal Cancer\|Stage IB Gastric Cancer\|Stage IIA Esophageal Cancer\|Stage IIA Gastric Cancer\|Stage IIB Esophageal Cancer\|Stage IIB Gastric Cancer\|Stage IIIA Esophageal Cancer\|Stage IIIA Gastric Cancer\|Stage IIIB Esophageal Cancer\|Stage IIIB Gastric Cancer\|Stage IIIC Esophageal Cancer\|Stage IIIC Gastric Cancer	April 27, 2011	Phase 2
NCT01670721	Sanofi\|Regeneron Pharmaceuticals	Colorectal Cancer Metastatic	August 2012	Phase 3
NCT00001014	National Institute of Allergy and Infectious Diseases (NIAID)	Pneumonia, Pneumocystis Carinii\|HIV Infections		Phase 3
NCT02296671	Washington University School of Medicine\|Gateway for Cancer Research	Esophagogastric Cancer	February 2015	Phase 2
NCT02545504	Gilead Sciences	Gastric Adenocarcinoma	October 13, 2015	Phase 3
NCT00042874	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	May 2002	Phase 1
NCT02042443	National Cancer Institute (NCI)	Adult Cholangiocarcinoma\|Advanced Adult Hepatocellular Carcinoma\|BCLC Stage C Adult Hepatocellular Carcinoma\|BCLC Stage D Adult Hepatocellular Carcinoma\|Hilar Cholangiocarcinoma\|Localized Non-Resectable Adult Liver Carcinoma\|Recurrent Adult Liver Carcinoma\|Recurrent Childhood Liver Cancer\|Recurrent Extrahepatic Bile Duct Carcinoma\|Recurrent Gallbladder Carcinoma\|Stage II Gallbladder Cancer\|Stage III Childhood Hepatocellular Carcinoma\|Stage IIIA Gallbladder Cancer\|Stage IIIB Gallbladder Cancer\|Stage IV Childhood Hepatocellular Carcinoma\|Stage IV Distal Bile Duct Cancer\|Stage IVA Gallbladder Cancer\|Stage IVB Gallbladder Cancer\|Unresectable Extrahepatic Bile Duct Carcinoma	February 2014	Phase 2
NCT03050814	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Colorectal Tumors\|Colorectal Neoplasms\|Colorectal Carcinoma\|Colorectal Adenocarcinoma\|Colorectal Cancer	April 5, 2017	Phase 2
NCT00040690	Medical Research Council\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	November 2008	Phase 2
NCT00002531	Johann Wolfgang Goethe University Hospital\|National Cancer Institute (NCI)	Leukemia	January 1993	Phase 2
NCT04005339	Georgetown University\|Ipsen	Advanced Biliary Tract Cancer	July 29, 2019	Phase 2
NCT01050426	Royal Marsden NHS Foundation Trust\|Merck Serono International SA	Pancreatic Cancer	March 2009	Phase 2
NCT03283761	Al B. Benson, III, MD\|Celgene Corporation\|Big Ten Cancer Research Consortium	Gastro-Esophageal Junction Adenocarcinoma\|Gastric Cancer	September 21, 2017	Phase 2
NCT01374425	Genentech, Inc.	Colorectal Cancer	August 2011	Phase 2
NCT02715531	Hoffmann-La Roche	Solid Tumor	April 6, 2016	Phase 1
NCT00001016	National Institute of Allergy and Infectious Diseases (NIAID)	Pneumonia, Pneumocystis Carinii\|HIV Infections		Phase 3
NCT00005608	Northwestern University\|National Cancer Institute (NCI)	Breast Cancer	February 2000	Phase 2
NCT00270543	Far Eastern Memorial Hospital	Stomach Neoplasms		Phase 2
NCT00861094	UNICANCER	Esophageal Cancer	March 2008	Phase 2\|Phase 3
NCT03402087	Bristol-Myers Squibb	Lupus\|Psoriatic Arthritis	January 8, 2018	Phase 1
NCT00000689	National Institute of Allergy and Infectious Diseases (NIAID)	Lymphoma, Non-Hodgkin\|HIV Infections		Phase 1
NCT00055822	The University of Texas Health Science Center at San Antonio\|National Cancer Institute (NCI)	Colorectal Cancer	October 2002	Phase 1\|Phase 2
NCT00416819	University of California, San Francisco\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors\|Lymphoma	September 2003	Not Applicable
NCT02420717	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Recurrent B Acute Lymphoblastic Leukemia\|Recurrent Ph-Like Acute Lymphoblastic Leukemia\|Refractory B Acute Lymphoblastic Leukemia\|Refractory Ph-Like Acute Lymphoblastic Leukemia	July 15, 2015	Phase 2
NCT01920737	Memorial Sloan Kettering Cancer Center\|Shire\|Duke University\|Weill Medical College of Cornell University\|Lehigh Valley Health Network	Leukemia	August 2013	Phase 2
NCT00524186	Roswell Park Cancer Institute\|Pfizer	Esophageal Cancer\|Gastric Cancer	May 2007	Phase 1
NCT04094688	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Adenocarcinoma	September 30, 2019	Phase 3
NCT00001498	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Breast Cancer\|Breast Neoplasms	February 1996	Phase 2
NCT00212589	Odense University Hospital	Colorectal Cancer	December 2002	Phase 3
NCT00000723	National Institute of Allergy and Infectious Diseases (NIAID)	Lymphoma, Non-Hodgkin\|HIV Infections		Not Applicable
NCT01473303	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Pancreatic Cancer	August 2012	Phase 1\|Phase 2
NCT00942266	Roswell Park Cancer Institute\|Merck Sharp & Dohme LLC	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	July 2009	Phase 2
NCT01959139	Southwest Oncology Group\|National Cancer Institute (NCI)\|Halozyme Therapeutics	Metastatic Pancreatic Adenocarcinoma	January 2014	Phase 1\|Phase 2
NCT05239741	Merck Sharp & Dohme LLC	Colorectal Neoplasms	April 2, 2022	Phase 3
NCT00501410	M.D. Anderson Cancer Center\|Bristol-Myers Squibb	Colorectal Cancer	April 23, 2007	Phase 1
NCT05009953	CSPC Ouyi Pharmaceutical Co., Ltd.	Advanced Biliary Tract Cancer\|Intrahepatic Cholangiocarcinoma\|Extrahepatic Cholangiocarcinoma\|Gallbladder Carcinoma	September 2021	Phase 2
NCT01271166	Novartis Pharmaceuticals\|Novartis	Advanced Colorectal Cancer	October 2007	Phase 1
NCT00000395	University of Alabama at Birmingham\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|Office of Dietary Supplements (ODS)	Rheumatoid Arthritis\|Adjuvant Arthritis	September 1996	Phase 2
NCT00782041	Sanofi	Uterine Neoplasms	January 2003	Phase 2
NCT02753127	Sumitomo Pharma Oncology, Inc.	Colorectal Cancer	June 2016	Phase 3
NCT00274872	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Colorectal Cancer	January 2004	Phase 2\|Phase 3
NCT02855788	Huashan Hospital\|Seattle Integrative Cancer Center	Metastatic Gastric Cancer\|Locally Advanced Gastric Cancer	May 2015	Phase 2
NCT04205968	Southwest Oncology Group\|National Cancer Institute (NCI)	Metastatic Small Intestinal Adenocarcinoma\|Stage III Small Intestinal Adenocarcinoma AJCC v8\|Stage IIIA Small Intestinal Adenocarcinoma AJCC v8\|Stage IIIB Small Intestinal Adenocarcinoma AJCC v8\|Stage IV Small Intestinal Adenocarcinoma AJCC v8	December 16, 2019	Phase 2
NCT00337389	Mast Therapeutics, Inc.	Metastatic Colorectal Cancer\|Colon Cancer\|Rectal Cancer	May 2006	Phase 3
NCT05378919	Lithuanian University of Health Sciences	Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX	June 1, 2015	Phase 2
NCT00539617	University of California, San Francisco\|Genentech, Inc.	Esophageal Cancer	October 5, 2007	Phase 2
NCT02392377	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Stage IB Esophageal Adenocarcinoma\|Stage IIA Esophageal Adenocarcinoma\|Stage IIB Esophageal Adenocarcinoma\|Stage IIIA Esophageal Adenocarcinoma\|Stage IIIB Esophageal Adenocarcinoma\|Stage IIIC Esophageal Adenocarcinoma	February 2015	Phase 2
NCT00002801	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	April 1996	Phase 1
NCT01063192	National Health Research Institutes, Taiwan\|National Taiwan University Hospital\|National Cheng-Kung University Hospital	Locally Advanced Pancreatic Cancer	November 2009	Phase 2
NCT00006050	UNICANCER	Colorectal Cancer\|Metastatic Cancer	April 4, 1999	Phase 2
NCT01263171	Cardiff University\|Cancer Research UK	Colorectal Cancer	April 2012	Phase 2
NCT00559741	Institut Cancerologie de l´Ouest\|National Cancer Institute (NCI)	Colorectal Cancer	October 2005	Phase 2
NCT00000998	National Institute of Allergy and Infectious Diseases (NIAID)	Pneumonia, Pneumocystis Carinii\|HIV Infections		Phase 1
NCT00008281	Sanofi\|National Cancer Institute (NCI)	Colorectal Cancer	October 2000	Phase 3
NCT00069121	Hoffmann-La Roche	Colorectal Cancer	April 18, 2003	Phase 3
NCT00571740	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer		Phase 2
NCT05493332	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Hepatocellular Carcinoma	September 2022	Phase 2
NCT01205022	City of Hope Medical Center\|National Cancer Institute (NCI)	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	April 2011	Phase 1
NCT00003260	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Colorectal Cancer	January 1998	Phase 3
NCT01670084	Mayo Clinic	B-cell Adult Acute Lymphoblastic Leukemia\|Blastic Phase Chronic Myelogenous Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia\|Untreated Adult Acute Lymphoblastic Leukemia	December 2012	Phase 2
NCT02870036	Haihe Biopharma Co., Ltd.	Advanced Solid Tumor\|Advanced+Metastatic Colorectal Cancer	October 2016	Phase 1
NCT00004997	National Institutes of Health Clinical Center (CC)	5q Minus Syndrome\|Myelodysplastic Syndrome	April 1998	Phase 2
NCT02333188	University of Chicago\|National Cancer Institute (NCI)	Adenocarcinoma of Unknown Primary\|Adult Cholangiocarcinoma\|Gallbladder Carcinoma\|Gastric Adenocarcinoma\|Malignant Gastrointestinal Neoplasm\|Metastatic Pancreatic Adenocarcinoma\|Pancreatic Adenocarcinoma\|Stage III Ampulla of Vater Cancer\|Stage III Pancreatic Cancer\|Stage IIIA Gallbladder Cancer\|Stage IIIA Gastric Cancer\|Stage IIIB Gallbladder Cancer\|Stage IIIB Gastric Cancer\|Stage IV Ampulla of Vater Cancer\|Stage IV Gallbladder Cancer\|Stage IV Gastric Cancer\|Stage IV Pancreatic Cancer	December 2014	Phase 1\|Phase 2
NCT02235324	University of Southern California\|National Cancer Institute (NCI)	Mucinous Adenocarcinoma of the Colon\|Mucinous Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Colon\|Signet Ring Adenocarcinoma of the Rectum\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	March 2015	Phase 2
NCT04164069	Anne Noonan\|Ohio State University Comprehensive Cancer Center	Advanced Colorectal Carcinoma\|Metastatic Colorectal Carcinoma\|Stage IV Colorectal Cancer AJCC v8\|Stage IVA Colorectal Cancer AJCC v8\|Stage IVB Colorectal Cancer AJCC v8\|Stage IVC Colorectal Cancer AJCC v8\|Stage II Colon Cancer\|Stage II Rectal Cancer\|Stage III Colon Cancer\|Stage III Rectal Cancer\|Esophageal Cancer\|Pancreatic Cancer\|Bile Duct Cancer\|Gastric Cancer\|Gall Bladder Cancer\|Small Bowel Adenocarcinoma	September 2, 2020	Phase 1
NCT00193219	SCRI Development Innovations, LLC\|Bristol-Myers Squibb	Colon Cancer	July 2005	Phase 2
NCT04393584	Blokhin´s Russian Cancer Research Center	Stomach Neoplasms\|Gastrointestinal Neoplasms\|Docetaxel\|Oxaliplatin\|Fluoruracil\|Irinotecan Hydrochloride	January 29, 2019	Phase 2\|Phase 3
NCT01959672	University of Nebraska\|National Cancer Institute (NCI)	Pancreatic Adenocarcinoma\|Resectable Pancreatic Carcinoma\|Stage I Pancreatic Cancer\|Stage IA Pancreatic Cancer\|Stage IB Pancreatic Cancer\|Stage II Pancreatic Cancer\|Stage IIA Pancreatic Cancer\|Stage IIB Pancreatic Cancer\|Stage III Pancreatic Cancer	September 2013	Phase 2
NCT00336024	Children´s Oncology Group\|National Cancer Institute (NCI)	Untreated Childhood Medulloblastoma\|Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor	October 22, 2007	Phase 3
NCT00002551	Southwest Oncology Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group\|Radiation Therapy Oncology Group\|North Central Cancer Treatment Group\|NCIC Clinical Trials Group\|Cancer and Leukemia Group B	Colorectal Cancer	March 1994	Phase 3
NCT00457691	Pfizer	Metastatic Colorectal Cancer	June 2007	Phase 3
NCT01362374	Genentech, Inc.	Neoplasms	July 11, 2011	Phase 1
NCT03785873	University of Michigan Rogel Cancer Center\|Ipsen\|Bristol-Myers Squibb	Biliary Tract Cancer	May 22, 2019	Phase 1\|Phase 2
NCT00707889	AbbVie (prior sponsor, Abbott)\|Genentech, Inc.\|AbbVie	Advanced Colorectal Cancer\|Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum	October 2008	Phase 2
NCT05568095	Arcus Biosciences, Inc.\|Gilead Sciences	Advanced Upper Gastrointestinal Tract Adenocarcinoma	November 2022	Phase 3
NCT03221426	Merck Sharp & Dohme LLC	Gastric Cancer\|Gastroesophageal Junction Cancer	October 9, 2017	Phase 3
NCT04252456	Gruppo Italiano per lo studio dei Carcinomi dell´Apparato Digerente	Advanced Colorectal Cancer	April 23, 2018	Not Applicable
NCT00075725	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia\|Childhood B Acute Lymphoblastic Leukemia	December 29, 2003	Phase 3
NCT02376452	Fudan University	Colorectal Carcinoma	September 2014	Phase 2
NCT00291785	CTI BioPharma	Colorectal Cancer	January 2004	Phase 1\|Phase 2
NCT03000374	Grupo Espanol Multidisciplinario del Cancer Digestivo\|Pivotal S.L.\|Amgen	Rectal Cancer	May 30, 2017	Phase 2
NCT03387111	ImmunityBio, Inc.	Squamous Cell Carcinoma	January 13, 2018	Phase 1\|Phase 2
NCT00002716	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	January 1996	Phase 3
NCT01814501	John Hays\|Amgen\|Ohio State University Comprehensive Cancer Center	Mucinous Adenocarcinoma of the Colon\|Mucinous Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Colon\|Signet Ring Adenocarcinoma of the Rectum\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	February 1, 2013	Phase 2
NCT00091312	Federation Francophone de Cancerologie Digestive\|National Cancer Institute (NCI)	Colorectal Cancer	June 2004	Phase 3
NCT00183911	University of Southern California\|National Cancer Institute (NCI)\|New York University	Gastric Adenocarcinoma\|Gastric Cancer	November 2003	Phase 2
NCT00321828	NSABP Foundation Inc\|National Cancer Institute (NCI)	Colorectal Cancer	March 2006	Phase 2
NCT00023998	National Cancer Institute (NCI)	Metastatic Osteosarcoma	July 2001	Phase 2
NCT00001579	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Lymphoma\|Neoplasms	June 1997	Phase 1
NCT00009815	University of Pittsburgh\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	December 1999	Phase 1
NCT00004252	Pfizer	Colorectal Cancer	November 1999	Phase 3
NCT01602016	University of Arkansas\|Arkansas Children´s Hospital Research Institute	Autism Spectrum Disorder\|Autistic Disorder\|Autism\|Asperger´s Syndrome\|Pervasive Development Disorders	May 2012	Phase 2
NCT03878524	OHSU Knight Cancer Institute\|Oregon Health and Science University	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Anatomic Stage IV Breast Cancer AJCC v8\|Anemia\|Ann Arbor Stage III Hodgkin Lymphoma\|Ann Arbor Stage III Non-Hodgkin Lymphoma\|Ann Arbor Stage IV Hodgkin Lymphoma\|Ann Arbor Stage IV Non-Hodgkin Lymphoma\|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Castration-Resistant Prostate Carcinoma\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Hematopoietic and Lymphoid System Neoplasm\|Locally Advanced Pancreatic Adenocarcinoma\|Metastatic Breast Carcinoma\|Metastatic Malignant Solid Neoplasm\|Metastatic Pancreatic Adenocarcinoma\|Myelodysplastic+Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Primary Myelofibrosis\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent Hematologic Malignancy\|Recurrent Hodgkin Lymphoma\|Recurrent Myelodysplastic Syndrome\|Recurrent Myelodysplastic+Myeloproliferative Neoplasm\|Recurrent Myeloproliferative Neoplasm\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Refractory Chronic Lymphocytic Leukemia\|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Refractory Chronic Myelomonocytic Leukemia\|Refractory Hematologic Malignancy\|Refractory Hodgkin Lymphoma\|Refractory Malignant Solid Neoplasm\|Refractory Myelodysplastic Syndrome\|Refractory Myelodysplastic+Myeloproliferative Neoplasm\|Refractory Non-Hodgkin Lymphoma\|Refractory Plasma Cell Myeloma\|Refractory Primary Myelofibrosis\|Refractory Small Lymphocytic Lymphoma\|Stage II Pancreatic Cancer AJCC v8\|Stage III Pancreatic Cancer AJCC v8\|Stage IV Pancreatic Cancer AJCC v8\|Stage IV Prostate Cancer AJCC v8\|Unresectable Pancreatic Adenocarcinoma	April 1, 2020	Phase 1
NCT00052585	National Cancer Institute (NCI)	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Mucinous Adenocarcinoma of the Colon\|Mucinous Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Colon\|Signet Ring Adenocarcinoma of the Rectum\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	October 2002	Phase 2
NCT00016952	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	April 2001	Phase 2
NCT01832948	Zhejiang Cancer Hospital	Metastatic Colorectal Cancer	January 2013	Phase 2
NCT00025337	National Cancer Institute (NCI)	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage III Colon Cancer\|Stage III Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	September 2001	Phase 3
NCT00002893	Medical Research Council\|National Cancer Institute (NCI)	Colorectal Cancer	June 1995	Phase 3
NCT00003558	Academisch Ziekenhuis Maastricht\|National Cancer Institute (NCI)	Carcinoma of Unknown Primary	August 1998	Phase 3
NCT03197571	ImmunityBio, Inc.	Urothelial Carcinoma	December 2017	Phase 1\|Phase 2
NCT00449163	University of Miami	Colorectal Cancer	March 1, 2006	Phase 2
NCT03206151	Taizhou Mabtech Pharmaceutical Co.,Ltd	Metastatic Colorectal Cancer	December 12, 2017	Phase 3
NCT00500292	Genzyme, a Sanofi Company\|Sanofi	Colorectal\|Cancer	March 2007	Phase 2
NCT00002722	European Organisation for Research and Treatment of Cancer - EORTC	Gastric Cancer	January 1996	Phase 2
NCT02551991	Ipsen	Pancreatic Cancer	October 19, 2015	Phase 2
NCT00106054	Pfizer	Colorectal Neoplasms\|Liver Neoplasms	January 2006	Phase 2
NCT00957905	National Cancer Institute (NCI)	Recurrent Extragonadal Seminoma\|Recurrent Malignant Extragonadal Germ Cell Tumor\|Recurrent Malignant Extragonadal Non-Seminomatous Germ Cell Tumor\|Recurrent Malignant Testicular Germ Cell Tumor\|Recurrent Ovarian Germ Cell Tumor\|Stage III Testicular Cancer\|Stage IV Extragonadal Non-Seminomatous Germ Cell Tumor\|Stage IV Extragonadal Seminoma\|Stage IV Ovarian Germ Cell Tumor	June 2009	Phase 2
NCT04248452	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Clinical Stage IV Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IV Gastric Cancer AJCC v8\|Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IVA Gastric Cancer AJCC v8\|Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IVB Gastric Cancer AJCC v8\|Metastatic Esophageal Adenocarcinoma\|Metastatic Gastric Adenocarcinoma\|Oligometastatic Esophageal Adenocarcinoma\|Oligometastatic Gastric Adenocarcinoma\|Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IV Gastric Cancer AJCC v8\|Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8	February 6, 2020	Phase 3
NCT00720512	Gruppo Oncologico del Nord-Ovest	Colorectal Cancer	June 2008	Phase 3
NCT03518112	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Philadelphia Chromosome Negative\|Recurrent B Acute Lymphoblastic Leukemia\|Refractory B Acute Lymphoblastic Leukemia	April 18, 2018	Phase 2
NCT05217069	Ludwig-Maximilians - University of Munich\|Merck KGaA, Darmstadt, Germany\|ClinAssess GmbH	Treatment Related Cancer	September 27, 2019	Phase 2
NCT01183663	M.D. Anderson Cancer Center\|Celgene	Advanced Cancers	August 2010	Phase 1
NCT03665441	ERYtech Pharma	Pancreatic Adenocarcinoma	September 15, 2018	Phase 3
NCT01803282	Gilead Sciences	Pancreatic Cancer\|Non-small Cell Lung Cancer\|Esophagogastric Cancer\|Colorectal Cancer\|Breast Cancer	March 29, 2013	Phase 1
NCT03167164	ImmunityBio, Inc.	Merkel Cell Carcinoma	December 2017	Phase 1\|Phase 2
NCT01150045	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	June 2010	Phase 3
NCT00003422	Medical Research Council\|NCIC Clinical Trials Group\|National Cancer Institute (NCI)	Colorectal Cancer	January 1998	Phase 3
NCT00778102	Hoffmann-La Roche	Colorectal Cancer	October 2008	Phase 2
NCT00233623	AstraZeneca	Metastatic Colorectal Cancer	July 2004	Phase 2
NCT00006455	Gustave Roussy, Cancer Campus, Grand Paris	Lymphoma	November 26, 1999	Phase 3
NCT02624726	Hellenic Oncology Research Group	Metastatic Colorectal Cancer	January 2016	Phase 2
NCT01227707	Hoffmann-La Roche	Colorectal Cancer	November 2005	Phase 2
NCT00381862	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Colorectal Cancer\|Nausea and Vomiting	June 2006	Phase 2
NCT00112658	UNICANCER	Pancreatic Cancer	November 2004	Phase 2\|Phase 3
NCT00003063	European Institute of Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	November 1991	Phase 3
NCT04299880	Sumitomo Pharma Oncology, Inc.	Oncology	February 24, 2020	Phase 1
NCT00660582	Per Pfeiffer\|Odense University Hospital	Metastatic Colorectal Cancer	April 2008	Phase 2
NCT00612586	Eli Lilly and Company\|Roche Pharma AG	Colorectal Cancer	February 2008	Phase 2
NCT00139230	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Sanofi	Squamous Cell Carcinoma\|Carcinoma of Head+Neck	January 1997	Phase 2
NCT00081289	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	March 2004	Phase 2
NCT00004897	Northwestern University\|National Cancer Institute (NCI)	Esophageal Cancer	October 1999	Phase 2
NCT00096135	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	November 2004	Not Applicable
NCT05292664	Andrew E. Place\|AbbVie\|Servier\|Children´s Cancer Research Fund\|University of Colorado, Denver\|Boston Children´s Hospital\|Dana-Farber Cancer Institute	Myelodysplastic Syndromes, de Novo\|Myelodysplastic Syndromes, Secondary\|Myelodysplastic Syndromes, Previously Treated\|Treatment-Related Acute Myeloid Leukemia\|Therapy-Related Myelodysplastic Syndrome\|Acute Lymphoblastic Leukemia, in Relapse\|Acute Lymphoblastic Leukemia With Failed Remission\|Lymphoblastic Lymphoma, in Relapse\|Lymphoblastic Lymphoma, Refractory\|Acute Leukemia of Ambiguous Lineage in Relapse\|Acute Leukemia of Ambiguous Lineage Not Having Achieved Remission	October 2022	Phase 1
NCT00559455	Sanofi	Carcinoma, Hepatocellular	September 2007	Phase 2
NCT00438737	European Organisation for Research and Treatment of Cancer - EORTC\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	January 2007	Phase 2
NCT00513188	University of Miami	Lymphoma	February 2007	Not Applicable
NCT02384850	GSO Global Clinical Research BV\|Karyopharm Therapeutics Inc	Colorectal Neoplasm	March 2015	Phase 1
NCT02785068	Merrimack Pharmaceuticals	Colorectal Cancer	July 2016	Phase 1\|Phase 2
NCT00006786	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	November 2000	Phase 2
NCT00602329	Abramson Cancer Center of the University of Pennsylvania\|National Cancer Institute (NCI)	Colorectal Cancer	February 2006	Phase 2
NCT00003305	Genzyme, a Sanofi Company\|National Cancer Institute (NCI)	Leukemia	July 1997	Phase 2
NCT05062317	M.D. Anderson Cancer Center	Liver Metastases	April 26, 2022	Phase 2
NCT03914625	National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|B Lymphoblastic Lymphoma\|Down Syndrome	June 28, 2019	Phase 3
NCT00060411	National Cancer Institute (NCI)	Mucinous Adenocarcinoma of the Colon\|Mucinous Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Colon\|Signet Ring Adenocarcinoma of the Rectum\|Stage IIIA Colon Cancer\|Stage IIIA Rectal Cancer\|Stage IIIB Colon Cancer\|Stage IIIB Rectal Cancer\|Stage IIIC Colon Cancer\|Stage IIIC Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	June 2003	Phase 1
NCT00769405	UNICANCER	Colorectal Cancer\|Primary Peritoneal Cavity Cancer	February 2008	Phase 3
NCT00023868	American College of Radiology Imaging Network\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	November 1, 2001	Phase 3
NCT02779283	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia	January 13, 2016	Phase 1
NCT02293109	Mehrdad Abedi, MD\|Amgen\|University of California, Davis	Contiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Untreated Adult Acute Lymphoblastic Leukemia	December 17, 2015	Phase 1
NCT03221400	Tarveda Therapeutics	Carcinoma\|Endometrial Adenocarcinoma\|Neoplasms\|Squamous Cell Carcinoma of the Anus\|Adenocarcinoma of the Pancreas\|Advanced Cancer\|Solid Tumor\|Solid Carcinoma\|Squamous Cell Carcinoma of the Cervix\|Squamous Cell Carcinoma\|Squamous Cell Carcinoma of the Vulva\|Squamous Cell Carcinoma of the Penis\|Gastric Cancer\|Gastric Adenocarcinoma\|Gastroesophageal Junction Adenocarcinoma\|Small-cell Lung Cancer\|Small Cell Lung Carcinoma\|Pancreatic Ductal Adenocarcinoma\|Pancreatic Adenocarcinoma	August 29, 2017	Phase 1\|Phase 2
NCT03175666	ImmunityBio, Inc.	Triple Negative Breast Cancer	December 2017	Phase 1\|Phase 2
NCT00049101	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	August 2002	Phase 1\|Phase 2
NCT01533324	Second Military Medical University	Carcinoma\|Liver Diseases\|Hepatocellular Carcinoma	November 2011	Phase 2
NCT02112916	National Cancer Institute (NCI)	Adult T Acute Lymphoblastic Leukemia\|Ann Arbor Stage II Adult Lymphoblastic Lymphoma\|Ann Arbor Stage II Childhood Lymphoblastic Lymphoma\|Ann Arbor Stage III Adult Lymphoblastic Lymphoma\|Ann Arbor Stage III Childhood Lymphoblastic Lymphoma\|Ann Arbor Stage IV Adult Lymphoblastic Lymphoma\|Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma\|Childhood T Acute Lymphoblastic Leukemia	September 30, 2014	Phase 3
NCT05329766	Arcus Biosciences, Inc.\|Gilead Sciences	Gastrointestinal Tract Malignancies	June 10, 2022	Phase 2
NCT00003776	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Sarcoma	December 1998	Phase 2
NCT00000973	National Institute of Allergy and Infectious Diseases (NIAID)\|Glaxo Wellcome	Toxoplasmosis, Cerebral\|HIV Infections		Phase 1
NCT00499850	Genzyme, a Sanofi Company\|Sanofi	Advanced Colorectal Carcinoma	August 2005	Phase 1
NCT00003215	Swiss Group for Clinical Cancer Research	Lymphoma	April 1997	Phase 3
NCT01074996	The Affiliated Hospital of the Chinese Academy of Military Medical Sciences	Pancreatic Cancer	February 2010	Phase 2
NCT00002494	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	May 1992	Phase 2
NCT01662869	Hoffmann-La Roche\|Genentech, Inc.	Gastric Cancer	November 2012	Phase 3
NCT00002514	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)\|Medical Research Council	Leukemia	April 1993	Phase 3
NCT00005944	UNICANCER	Colorectal Cancer\|Metastatic Cancer\|Primary Peritoneal Cavity Cancer	July 1, 1999	Phase 2
NCT02553460	St. Jude Children´s Research Hospital\|Gateway for Cancer Research\|Baylor College of Medicine	Acute Lymphoblastic Leukemia	January 29, 2016	Phase 1\|Phase 2
NCT00392834	AIDS Malignancy Consortium\|National Cancer Institute (NCI)\|The Emmes Company, LLC	Lymphoma	September 2006	Phase 2
NCT03406299	National Health Research Institutes, Taiwan	Biliary Tract Neoplasms	April 19, 2018	Phase 2
NCT04008030	Bristol-Myers Squibb\|Ono Pharmaceutical Co. Ltd	Metastatic Colorectal Cancer	August 5, 2019	Phase 3
NCT04034459	Ludwig-Maximilians - University of Munich	Metastatic Colorectal Cancer	November 25, 2016	Phase 2
NCT03977233	UNC Lineberger Comprehensive Cancer Center	Pancreatic Ductal Adenocarcinoma (PDAC)\|Cancer of Pancreas\|Pancreatic Cancer, Adult\|Pancreas Adenocarcinoma\|Pancreatic Neoplasms\|Pancreatic Cancer Non-resectable\|Pancreatic Cancer Resectable	June 12, 2019	Phase 2
NCT01522612	European Organisation for Research and Treatment of Cancer - EORTC\|Merck KGaA, Darmstadt, Germany	Colorectal Cancer Metastatic	April 2013	Phase 2
NCT02413853	University of Southern California\|National Cancer Institute (NCI)\|Prism Pharma Co., Ltd.	Colorectal Adenocarcinoma\|Stage IVA Colorectal Cancer\|Stage IVB Colorectal Cancer	November 2015	Phase 2
NCT00020488	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	February 2001	Phase 1
NCT02935764	Fudan University	Colorectal Carcinoma	October 2016	Phase 3
NCT00002552	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm	October 1993	Phase 2
NCT03127124	NantPharma, LLC	Pancreatic Adenocarcinoma Metastatic	February 27, 2018	Phase 1\|Phase 2
NCT05146739	National Cancer Institute (NCI)\|Childrens Oncology Group (COG)\|LLS PedAL LLC	Down Syndrome\|Recurrent Acute Myeloid Leukemia\|Recurrent Mixed Phenotype Acute Leukemia\|Recurrent Myelodysplastic Syndrome\|Refractory Acute Myeloid Leukemia\|Refractory Mixed Phenotype Acute Leukemia\|Refractory Myelodysplastic Syndrome\|Therapy-Related Acute Myeloid Leukemia\|Therapy-Related Myelodysplastic Syndrome	August 19, 2022	Phase 1
NCT00103285	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Childhood B Acute Lymphoblastic Leukemia	April 11, 2005	Phase 3
NCT02641691	Washington University School of Medicine	Cancer of Rectum\|Cancer of the Rectum\|Neoplasm, Rectum\|Rectal Cancer\|Rectum Cancer\|Rectum Neoplasms\|Adenocarcinoma of the Rectum	May 27, 2016	Phase 2
NCT00305188	Sanofi	Metastases\|Colorectal Neoplasms\|Colorectal Carcinoma	December 2005	Phase 3
NCT00303628	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Adenocarcinoma of the Rectum\|Stage II Rectal Cancer\|Stage III Rectal Cancer	February 17, 2006	Phase 3
NCT03880877	Kaohsiung Medical University Chung-Ho Memorial Hospital	Metastatic Colorectal Cancer	February 26, 2019	Phase 2
NCT01737671	M.D. Anderson Cancer Center	Brain Tumor\|Malignant Neoplasm of Fourth Ventricle of Brain	December 27, 2012	Early Phase 1
NCT02620423	Oncolytics Biotech	Pancreatic Adenocarcinoma	December 2015	Phase 1
NCT00002102	U.S. Bioscience\|NIH AIDS Clinical Trials Information Service	Pneumonia, Pneumocystis Carinii\|HIV Infections		Not Applicable
NCT05564403	National Cancer Institute (NCI)	Recurrent Biliary Tract Carcinoma\|Recurrent Distal Bile Duct Adenocarcinoma\|Recurrent Gallbladder Carcinoma\|Recurrent Intrahepatic Cholangiocarcinoma\|Stage III Distal Bile Duct Cancer AJCC v8\|Stage III Hilar Cholangiocarcinoma AJCC v8\|Stage III Intrahepatic Cholangiocarcinoma AJCC v8\|Stage IV Distal Bile Duct Cancer AJCC v8\|Stage IV Hilar Cholangiocarcinoma AJCC v8\|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8\|Unresectable Biliary Tract Carcinoma\|Unresectable Distal Bile Duct Adenocarcinoma\|Unresectable Gallbladder Carcinoma\|Unresectable Intrahepatic Cholangiocarcinoma	December 9, 2022	Phase 2
NCT00005585	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	April 2000	Phase 3
NCT03464968	Seoul National University Bundang Hospital	Biliary Cancer Metastatic	July 29, 2015	Phase 2
NCT00004005	St. Jude Children´s Research Hospital\|National Cancer Institute (NCI)	Carcinoma of Unknown Primary\|Colorectal Cancer\|Unspecified Adult Solid Tumor, Protocol Specific\|Unspecified Childhood Solid Tumor, Protocol Specific	September 1998	Phase 2
NCT00654160	Mayo Clinic\|National Cancer Institute (NCI)	Anal Cancer\|Carcinoma of the Appendix\|Colorectal Cancer\|Esophageal Cancer\|Extrahepatic Bile Duct Cancer\|Gallbladder Cancer\|Gastric Cancer\|Gastrointestinal Carcinoid Tumor\|Gastrointestinal Stromal Tumor\|Liver Cancer\|Pancreatic Cancer\|Small Intestine Cancer	June 2008	Phase 1
NCT01289821	Bayer	Colorectal Neoplasms	February 2011	Phase 2
NCT04762953	University of California, Irvine	Gastric Cancer\|Peritoneal Carcinomatosis\|Gastroesophageal Junction Adenocarcinoma	February 18, 2021	Phase 2
NCT01653470	Bristol-Myers Squibb	Cancer	October 12, 2012	Phase 1
NCT00002793	Johann Wolfgang Goethe University Hospital\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	January 1991	Phase 3
NCT05026905	National Health Research Institutes, Taiwan\|China Medical University Hospital\|National Cheng-Kung University Hospital\|Kaohsiung Medical University Chung-Ho Memorial Hospital	Phase II, Open-label, Parallel 2-arm, Multi-center	December 28, 2021	Phase 2
NCT00002783	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Gastric Cancer	May 1996	Phase 2
NCT00634322	BTG International Inc.\|M.D. Anderson Cancer Center	Osteosarcoma	October 2008	Phase 2
NCT00006015	National Cancer Institute (NCI)	Colorectal Cancer	May 2000	Phase 2
NCT00005979	UNICANCER\|Federation Francophone de Cancerologie Digestive	Colorectal Cancer	July 22, 1998	Phase 3
NCT03329248	ImmunityBio, Inc.	Pancreatic Cancer	November 6, 2017	Phase 1\|Phase 2
NCT02704520	Royal Marsden NHS Foundation Trust	Rectal Cancer	March 2016	Phase 2\|Phase 3
NCT00082797	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	February 2005	Phase 2
NCT00008060	Medical Research Council\|National Cancer Institute (NCI)	Colorectal Cancer	May 2000	Phase 3
NCT01896531	Genentech, Inc.	Gastric Cancer	August 14, 2013	Phase 2
NCT00755118	University Hospital of Crete	Colorectal Cancer	October 2008	Phase 2
NCT00975897	Medical Research Council\|National Cancer Institute (NCI)	Colorectal Cancer	July 2009	Phase 2\|Phase 3
NCT00317408	European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma\|National Cancer Institute (NCI)	Lymphoma	April 2004	Not Applicable
NCT05567835	Baylor College of Medicine	Gastric Adenocarcinoma\|Gastroesophageal Junction Adenocarcinoma	January 2023	Phase 2
NCT00556413	Institut du Cancer de Montpellier - Val d´Aurelle	Colorectal Cancer	September 2005	Phase 2
NCT01333033	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Esophageal Cancer	July 2011	Phase 2
NCT04442984	Blokhin´s Russian Cancer Research Center	Gastric Carcinoma Stage IV\|Esophagogastric Junction Adenocarcinoma Stage IV	November 3, 2019	Phase 2
NCT04961970	Shi Ming\|Sun Yat-sen University	Intrahepatic Cholangiocarcinoma	July 9, 2021	Phase 3
NCT00052910	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Esophageal Cancer\|Gastric Cancer	December 2002	Phase 3
NCT03110510	Samsung Medical Center	Biliary Tract Cancer	September 6, 2019	Phase 2
NCT02141295	Hoffmann-La Roche	Colorectal Cancer	June 30, 2014	Phase 2
NCT00759226	CONKO-Studiengruppe\|Eli Lilly and Company\|medac GmbH	Esophageal Cancer	July 2002	Phase 2
NCT03791905	Mian XI\|Sun Yat-sen University	Neoplasm, Esophageal\|Squamous Cell Carcinoma	January 15, 2019	Phase 2
NCT01269216	Yonsei University	Rectal Cancer	October 2008	Phase 2
NCT00719797	Gruppo Oncologico del Nord-Ovest	Colorectal Cancer	July 2008	Phase 3
NCT02344810	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)\|ECOG-ACRIN Cancer Research Group	Adenocarcinoma of the Esophagus\|Adenocarcinoma of the Gastroesophageal Junction\|Diffuse Adenocarcinoma of the Stomach\|Gastrointestinal Cancer\|Intestinal Adenocarcinoma of the Stomach\|Mixed Adenocarcinoma of the Stomach\|Stage IIIA Esophageal Cancer\|Stage IIIA Gastric Cancer\|Stage IIIB Esophageal Cancer\|Stage IIIB Gastric Cancer\|Stage IIIC Esophageal Cancer\|Stage IIIC Gastric Cancer\|Stage IV Esophageal Cancer\|Stage IV Gastric Cancer	March 6, 2015	Phase 1\|Phase 2
NCT00742924	Children´s Oncology Group\|National Cancer Institute (NCI)	Sarcoma	August 2008	Phase 1
NCT01747551	Dana-Farber Cancer Institute	Esophageal Cancer\|Gastric Cancer	January 2013	Phase 2
NCT04723134	Joseph Boykin, MD\|George Mason University\|Central Arkansas Veterans Healthcare System\|Hunter Holmes Mcguire Veteran Affairs Medical Center	Diabetic Foot Ulcer	December 1, 2021	Phase 2
NCT00354978	M.D. Anderson Cancer Center\|Genentech, Inc.\|Pfizer	Colorectal Cancer	January 2005	Phase 2
NCT05148195	Jiangsu Simcere Pharmaceutical Co., Ltd.	Advanced Solid Tumor	December 22, 2021	Phase 2
NCT00000966	Pfizer\|National Institute of Allergy and Infectious Diseases (NIAID)	Toxoplasmosis, Cerebral\|HIV Infections		Phase 1
NCT00309543	Austrian Breast & Colorectal Cancer Study Group	Colon Cancer Stage II	November 1993	Phase 3
NCT01529164	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Simcere Pharmaceutical Co., Ltd	Colorectal Cancer	October 2011	Phase 2
NCT03069950	Memorial Sloan Kettering Cancer Center\|The Cleveland Clinic\|Oregon Health and Science University\|Queens Cancer Center of Queens Hospital\|Washington University School of Medicine	Colorectal Adenocarcinoma Metastatic to the Liver	February 28, 2017	Phase 2
NCT00390416	Memorial Sloan Kettering Cancer Center\|Sanofi\|Genentech, Inc.	Stomach Neoplasms\|Esophageal Neoplasms	October 2006	Phase 2
NCT00786643	Accelerated Community Oncology Research Network\|InterMune	Colorectal Cancer	February 2006	Phase 2
NCT03488225	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia in Remission\|B Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative	March 28, 2018	Phase 2
NCT01821612	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Acinar Cell Adenocarcinoma of the Pancreas\|Duct Cell Adenocarcinoma of the Pancreas\|Recurrent Pancreatic Cancer\|Stage II Pancreatic Cancer\|Stage III Pancreatic Cancer	May 2013	Early Phase 1
NCT00138177	National Cancer Institute (NCI)	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage III Colon Cancer\|Stage III Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	July 2005	Phase 1
NCT00462501	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)\|Genentech, Inc.	Colorectal Cancer	March 2007	Not Applicable
NCT02106650	Acrotech Biopharma Inc.\|Axis Clinicals Limited	Relapsed Peripheral T-Cell Lymphoma\|Refractory Peripheral T-Cell Lymphoma	July 2014	Phase 2
NCT00797485	Southern Italy Cooperative Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	July 2008	Phase 3
NCT00000714	National Institute of Allergy and Infectious Diseases (NIAID)	Pneumonia, Pneumocystis Carinii\|HIV Infections		Phase 3
NCT05192889	St. Jude Children´s Research Hospital\|AbbVie	Refractory Acute Lymphoblastic Leukemia\|Relapsed Acute Lymphoblastic Leukemia	August 25, 2022	Phase 1\|Phase 2
NCT00002571	Southwest Oncology Group\|National Cancer Institute (NCI)	Lymphoma	June 1994	Phase 2
NCT00849615	Krankenhaus Nordwest	Gastric Cancer\|Adenocarcinoma of the Esophagogastric Junction	February 2009	Phase 2
NCT05379595	Janssen Research & Development, LLC	Advanced or Metastatic Colorectal Cancer	July 29, 2022	Phase 1\|Phase 2
NCT00199797	Ludwig Institute for Cancer Research	Colorectal Cancer	April 18, 2005	Phase 1
NCT00004099	European Organisation for Research and Treatment of Cancer - EORTC	Gastric Cancer	July 1999	Phase 3
NCT02620865	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Metastatic Pancreatic Adenocarcinoma\|Recurrent Pancreatic Carcinoma\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer	December 2015	Phase 1\|Phase 2
NCT00084838	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Central Nervous System Tumor, Pediatric	February 2003	Phase 2
NCT03493048	Sun Yat-sen University	Colo-rectal Cancer\|Liver Metastases	January 1, 2018	Phase 2
NCT00005596	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	April 2000	Phase 3
NCT03020030	Dana-Farber Cancer Institute\|Servier	Acute Lymphoblastic Leukemia, Pediatric	March 3, 2017	Phase 3
NCT00625092	Masonic Cancer Center, University of Minnesota	Peritoneal Cavity Cancer	October 2007	Phase 1
NCT03006432	Federation Francophone de Cancerologie Digestive\|UNICANCER\|GERCOR - Multidisciplinary Oncology Cooperative Group	OESOPHAGO-GASTRIC CARCINOMA	December 2016	Phase 3
NCT01193452	Fudan University	Colorectal Cancer	August 2010	Phase 2
NCT00022737	National Cancer Institute (NCI)	Childhood Acute Lymphoblastic Leukemia in Remission\|Recurrent Childhood Acute Lymphoblastic Leukemia	October 2002	Phase 3
NCT00002317	U.S. Bioscience\|NIH AIDS Clinical Trials Information Service	Pneumonia, Pneumocystis Carinii\|HIV Infections		Not Applicable
NCT01226719	SCRI Development Innovations, LLC\|Amgen	Colorectal Cancer	December 2010	Phase 2
NCT05253651	Seagen Inc.\|Merck Sharp & Dohme LLC	Colorectal Neoplasms	November 30, 2022	Phase 3
NCT01206530	Abramson Cancer Center of the University of Pennsylvania	Rectal Cancer\|Colon Cancer\|Metastasis\|Adenocarcinoma	September 2010	Phase 1\|Phase 2
NCT00862784	Eli Lilly and Company	Colorectal Carcinoma	April 2009	Phase 2
NCT00974792	Cancer Research UK\|National Cancer Institute (NCI)	Lymphoma	January 2006	Phase 2
NCT02366819	University of Chicago\|National Cancer Institute (NCI)	Esophageal Adenocarcinoma\|Gastric Adenocarcinoma\|Stage IIB Gastric Cancer\|Stage IIIA Esophageal Adenocarcinoma\|Stage IIIA Gastric Cancer\|Stage IIIB Esophageal Adenocarcinoma\|Stage IIIB Gastric Cancer\|Stage IIIC Esophageal Adenocarcinoma\|Stage IIIC Gastric Cancer	December 11, 2014	Phase 4
NCT01928290	Washington University School of Medicine	Stomach Neoplasms\|Esophageal Neoplasms	November 8, 2013	Phase 2
NCT00016978	National Cancer Institute (NCI)	Colorectal Cancer	April 2001	Phase 2
NCT01930552	Sanofi\|Regeneron Pharmaceuticals	Neoplasm Malignant	September 2013	Phase 1
NCT00004885	European Organisation for Research and Treatment of Cancer - EORTC	Colorectal Cancer	July 1999	Phase 3
NCT00268333	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Colorectal Cancer	August 2005	Phase 2
NCT02872116	Bristol-Myers Squibb\|Ono Pharmaceutical Co. Ltd	Gastric Cancer\|Gastroesophageal Junction Cancer\|Esophageal Adenocarcinoma	October 12, 2016	Phase 3
NCT02143219	Institut Cancerologie de l´Ouest	Pancreatic Metastatic Cancer\|Toxicity	July 31, 2014	Phase 2
NCT03699319	David Bajor\|Case Comprehensive Cancer Center	Pancreatic Cancer	December 7, 2018	Phase 1\|Phase 2
NCT00068692	National Cancer Institute (NCI)	Rectal Mucinous Adenocarcinoma\|Rectal Signet Ring Cell Adenocarcinoma\|Recurrent Rectal Carcinoma\|Stage IIA Rectal Cancer AJCC v7\|Stage IIB Rectal Cancer AJCC v7\|Stage IIC Rectal Cancer AJCC v7\|Stage IIIA Rectal Cancer AJCC v7\|Stage IIIB Rectal Cancer AJCC v7\|Stage IIIC Rectal Cancer AJCC v7\|Stage IVA Rectal Cancer AJCC v7\|Stage IVB Rectal Cancer AJCC v7	October 15, 2003	Phase 3
NCT03515941	Tannaz Armaghany\|Baylor College of Medicine	Gastrointestinal Cancer	June 22, 2018	Early Phase 1
NCT00627666	Asan Medical Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	January 2003	Phase 2
NCT02506231	Rabin Medical Center	Graft vs Host Disease\|Allogeneic Hematopoietic Cell Transplantation\|Mucositis	October 2015	Phase 2\|Phase 3
NCT01576705	Institut Jerome Lejeune\|Hôpital Cochin\|Central Hospital, Nancy, France	Down Syndrome	April 2, 2012	Phase 3
NCT02500940	Taichung Veterans General Hospital\|Fujian Cancer Hospital	Nasopharyngeal Carcinoma	May 2015	Phase 3
NCT03800693	Emory University\|Hematology+Oncology Pharmacy Association\|University of Pittsburgh	Malignant Digestive System Neoplasm	March 14, 2019	Phase 2
NCT00075738	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Esophageal Cancer	October 2003	Phase 2
NCT00056030	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	December 2004	Phase 2
NCT03300609	University of Southern California\|National Cancer Institute (NCI)\|Amgen	Colorectal Adenocarcinoma\|RAS Wild Type\|Stage III Colorectal Cancer AJCC v7\|Stage IIIA Colorectal Cancer AJCC v7\|Stage IIIB Colorectal Cancer AJCC v7\|Stage IIIC Colorectal Cancer AJCC v7\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	February 27, 2018	Phase 3
NCT04430738	Seagen Inc.	Colorectal Carcinoma\|Gastric Adenocarcinoma\|GEJ Adenocarcinoma\|Esophageal Adenocarcinoma\|Cholangiocarcinoma\|Gallbladder Carcinoma	September 15, 2020	Phase 1\|Phase 2
NCT01498289	Southwest Oncology Group\|National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Esophageal Cancer\|Gastric Cancer	February 2012	Phase 2
NCT02046538	Weill Medical College of Cornell University\|Sanofi	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum	February 2014	Phase 2
NCT03169790	ImmunityBio, Inc.	Non Hodgkin Lymphoma	December 2017	Phase 1\|Phase 2
NCT00004860	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	June 2000	Phase 2
NCT00508872	M.D. Anderson Cancer Center\|Sanofi	Colorectal Liver Metastases	November 2005	Phase 2
NCT00281944	National Cancer Institute (NCI)	Childhood Central Nervous System Choriocarcinoma\|Childhood Central Nervous System Embryonal Tumor\|Childhood Central Nervous System Germ Cell Tumor\|Childhood Central Nervous System Germinoma\|Childhood Central Nervous System Mixed Germ Cell Tumor\|Childhood Central Nervous System Teratoma\|Childhood Central Nervous System Yolk Sac Tumor\|Recurrent Childhood Brain Stem Glioma\|Recurrent Childhood Central Nervous System Embryonal Tumor\|Unspecified Childhood Solid Tumor, Protocol Specific	September 2005	Phase 1
NCT00002578	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Lymphoma	August 1994	Phase 2
NCT00640081	Cheryl Pugh\|Medical Research Council	Colorectal Cancer	July 2007	Phase 2
NCT02573220	University of Chicago\|National Cancer Institute (NCI)	Stage IVA Colorectal Cancer\|Stage IVB Colorectal Cancer	June 2015	Phase 1
NCT01926197	Stanford University	Pancreatic Cancer	August 14, 2013	Phase 3
NCT00096278	National Cancer Institute (NCI)\|NSABP Foundation Inc	Colon Adenocarcinoma\|Stage IIA Colon Cancer AJCC v7\|Stage IIB Colon Cancer AJCC v7\|Stage IIC Colon Cancer AJCC v7\|Stage IIIA Colon Cancer AJCC v7\|Stage IIIB Colon Cancer AJCC v7\|Stage IIIC Colon Cancer AJCC v7	September 15, 2004	Phase 3
NCT03606928	Ruijin Hospital	Gastric Cancer	July 1, 2018	Phase 1\|Phase 2
NCT00003728	European Organisation for Research and Treatment of Cancer - EORTC\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	December 1998	Phase 3
NCT01802645	Technische Universität Dresden	Colorectal Cancer	March 2013	Phase 2
NCT01167725	Walter Reed Army Medical Center\|National Cancer Institute (NCI)	Colorectal Cancer	August 2010	Phase 3
NCT03872947	Toray Industries, Inc	Solid Tumor\|Colorectal Cancer\|Cholangiocarcinoma\|Bladder Cancer\|Ovarian Cancer\|Gastric Cancer\|Palpable Subcutaneous Malignant Lesions\|Renal Cell Carcinoma\|Melanoma\|Epithelial Ovarian Cancer\|Primary Peritoneal Cancer\|Fallopian Tube Cancer	April 26, 2019	Phase 1
NCT01053390	Shanghai Jiao Tong University School of Medicine\|Xuanwu Hospital, Beijing\|Capital Medical University\|Peking University First Hospital\|Tianjin Medical University Cancer Institute and Hospital\|The First Affiliated Hospital of Dalian Medical University\|China Medical University, China\|The first clinical college of harbin medical university\|The Second Affiliated Hospital of Harbin Medical University\|Shengjing Hospital\|Jilin University\|The people´s hospital of Heilongjiang province\|Eastern Hepatobiliary Surgery Hospital\|Shanghai Changzheng Hospital\|Shandong Provincial Hospital\|Qilu Hospital of Shandong University\|Air Force Military Medical University, China\|Tang-Du Hospital\|Qinghai People´s Hospital\|Affiliated Hospital of Qinghai University\|First Affiliated Hospital of Chongqing Medical University\|Daping Hospital and the Research Institute of Surgery of the Third Military Medical University\|First People´s Hospital of Kunming\|Lanzhou university second hospital\|Xi´an Central Hospital\|The first people´s hospital of Guiyang\|Southwest Hospital, China\|The First Affiliated Hospital of Kunming Medical College	Gallbladder Neoplasms	October 2009	Phase 3
NCT00737373	Krankenhaus Nordwest	Gastric Cancer\|Adenocarcinoma of the Esophagogastric Junction	August 2007	Phase 2
NCT00003783	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	March 1999	Phase 2
NCT00499369	National Cancer Institute (NCI)\|North Central Cancer Treatment Group\|Cancer and Leukemia Group B\|Eastern Cooperative Oncology Group\|NCIC Clinical Trials Group	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	June 2007	Phase 3
NCT00040391	Celgene Corporation\|Pfizer	Colorectal Neoplasms\|Diarrhea	June 2002	Phase 2
NCT00016198	Prologue Research International\|National Cancer Institute (NCI)	Colorectal Cancer	May 2001	Phase 2
NCT02015819	City of Hope Medical Center\|National Cancer Institute (NCI)	Adult Anaplastic Astrocytoma\|Adult Anaplastic Oligodendroglioma\|Adult Giant Cell Glioblastoma\|Adult Glioblastoma\|Adult Gliosarcoma\|Recurrent Adult Brain Tumor\|Anaplastic Oligoastrocytoma	October 7, 2014	Phase 1
NCT00002532	Hannover Medical School\|National Cancer Institute (NCI)	Leukemia	January 1993	Phase 2
NCT00133991	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	July 2005	Phase 2
NCT04821284	Thomas Jefferson University	Locally Advanced Pancreatic Ductal Adenocarcinoma\|Metastatic Pancreatic Ductal Adenocarcinoma\|Stage II Pancreatic Cancer AJCC v8\|Stage IIA Pancreatic Cancer AJCC v8\|Stage IIB Pancreatic Cancer AJCC v8\|Stage III Pancreatic Cancer AJCC v8\|Stage IV Pancreatic Cancer AJCC v8\|Unresectable Pancreatic Ductal Adenocarcinoma	December 6, 2021	Phase 1\|Phase 2
NCT00002816	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	December 1996	Phase 3
NCT02620800	Celgene	Metastatic Pancreas Adenocarcinoma	January 18, 2016	Phase 1
NCT01490866	SCRI Development Innovations, LLC\|Pfizer	Colorectal Cancer	January 2012	Phase 2
NCT02099188	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano\|Regione Lombardia	Unresectable Sinonasal Tumors	November 2013	Phase 2
NCT00046995	Groupe Regional d´Etudes du Cancer Colorectal\|National Cancer Institute (NCI)	Colorectal Cancer	May 2001	Phase 3
NCT00003001	Stony Brook University\|National Cancer Institute (NCI)	Colorectal Cancer	April 1997	Phase 1\|Phase 2
NCT03337087	Academic and Community Cancer Research United\|National Cancer Institute (NCI)	Metastatic Biliary Tract Carcinoma\|Metastatic Colorectal Carcinoma\|Metastatic Gastroesophageal Junction Adenocarcinoma\|Metastatic Malignant Digestive System Neoplasm\|Metastatic Pancreatic Adenocarcinoma\|Stage IV Colorectal Cancer AJCC v7\|Stage IV Pancreatic Cancer AJCC v6 and v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	November 2, 2018	Phase 1\|Phase 2
NCT01360086	Federation Francophone de Cancerologie Digestive	Adenocarcinoma of the Gastroesophageal Junction\|Gastric Cancer	June 2011	Phase 2
NCT03959085	Children´s Oncology Group\|National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|B Lymphoblastic Lymphoma\|Central Nervous System Leukemia\|Mixed Phenotype Acute Leukemia\|Testicular Leukemia	October 28, 2019	Phase 3
NCT01964755	University of Miami	Epstein Barr Virus Associated Non Hodgkin´s Lymphoma\|Epstein Barr Virus Associated Hodgkin´s Lymphoma\|Post-Transplant Lymphoproliferative Disease	April 21, 2009	Phase 2
NCT01913639	Memorial Sloan Kettering Cancer Center\|Bayer	Esophageal Cancer\|Gastric Cancer	July 2013	Phase 2
NCT00416767	Federation Francophone de Cancerologie Digestive	Gastrointestinal Carcinoid Tumor\|Islet Cell Tumor\|Neoplastic Syndrome	May 2004	Phase 2
NCT00478946	Poniard Pharmaceuticals	Colorectal Cancer	April 2006	Phase 1\|Phase 2
NCT00004127	University of Chicago\|National Cancer Institute (NCI)	Esophageal Cancer\|Gastric Cancer	February 2000	Phase 2
NCT03751176	Grupo Espanol Multidisciplinario del Cancer Digestivo\|Amgen\|Pivotal S.L.	Colorectal Cancer Metastatic	November 8, 2018	Phase 2
NCT03503604	SuZhou Stainwei Biotech Inc.	Solid Tumors	May 1, 2018	Phase 1
NCT00448682	University of Miami	Gastric Cancer	June 2005	Phase 2
NCT00005068	Mayo Clinic\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	January 2000	Phase 1
NCT00004913	Northwestern University\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	January 2000	Phase 1
NCT00061815	Eli Lilly and Company\|Bristol-Myers Squibb	Colorectal Cancer	March 2003	Phase 3
NCT02008656	Memorial Sloan Kettering Cancer Center\|Colon and Rectal Surgery Inc.\|The Cleveland Clinic\|John Muir Health\|Oregon Health and Science University\|St. Joseph Hospital of Orange\|University of California, Irvine\|University of California, San Francisco\|University of Chicago\|University of South Florida\|University of Vermont\|University of Washington\|Medstar Health Research Institute\|Washington University School of Medicine\|Creighton University Medical Center\|The Methodist Hospital Research Institute\|University of Rochester\|University of Virginia\|St. Paul´s Hospital\|St. Joseph, Florida\|Cleveland Clinic Florida\|University of Colorado, Denver\|University of Michigan	Rectal Cancer	November 2013	Phase 2
NCT00209625	Hokkaido Gastrointestinal Cancer Study Group	Colorectal Cancer	April 2000	Phase 1\|Phase 2
NCT00002523	European Organisation for Research and Treatment of Cancer - EORTC	Colorectal Cancer	April 1993	Phase 3
NCT00002691	Memorial Sloan Kettering Cancer Center	Lymphoma	August 1995	Phase 2
NCT01216644	Krankenhaus Nordwest	Gastric Cancer	August 2010	Phase 2\|Phase 3
NCT00001449	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Neoplasms	September 1995	Phase 1
NCT00873275	City of Hope Medical Center\|National Cancer Institute (NCI)	Colorectal Cancer	March 11, 2009	Phase 1
NCT04539808	OHSU Knight Cancer Institute\|Oregon Health and Science University	Borderline Resectable Pancreatic Carcinoma\|Locally Advanced Unresectable Pancreatic Adenocarcinoma\|Resectable Pancreatic Ductal Adenocarcinoma\|Stage 0 Pancreatic Cancer AJCC v8\|Stage I Pancreatic Cancer AJCC v8\|Stage IA Pancreatic Cancer AJCC v8\|Stage IB Pancreatic Cancer AJCC v8\|Stage III Pancreatic Cancer AJCC v8\|Stage IV Pancreatic Cancer AJCC v8	May 27, 2021	Phase 2
NCT02606539	Maher elesawi kamel elesawi\|Mansoura University	Gestational Trophoblastic Neoplasms	September 2015	Phase 2\|Phase 3
NCT00126191	Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital	Burkitt Lymphoma\|Non-Hodgkins Lymphoma\|Atypical Burkitt Lymphoma	July 2005	Phase 2
NCT02896907	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Pancreatic Adenocarcinoma\|Recurrent Pancreatic Carcinoma\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer\|Unresectable Pancreatic Carcinoma	October 18, 2016	Early Phase 1
NCT02508077	City of Hope Medical Center\|National Cancer Institute (NCI)	Recurrent Colorectal Carcinoma\|Stage IVA Colorectal Cancer\|Stage IVB Colorectal Cancer	February 16, 2016	Phase 2
NCT00072553	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Colorectal Cancer	September 2003	Phase 2
NCT00878254	University of Miami	Mantle-Cell Lymphoma	March 25, 2009	Phase 2
NCT00544414	City of Hope Medical Center\|National Cancer Institute (NCI)	Head and Neck Cancer	June 7, 2000	Phase 2
NCT04354662	Tianjin Medical University Cancer Institute and Hospital	Gastric Cancer	September 26, 2019	Phase 2
NCT00065117	AstraZeneca	Colorectal Neoplasms\|Metastases, Neoplasm	September 2003	Phase 2
NCT00587873	Memorial Sloan Kettering Cancer Center	Hodgkin´s Disease	March 1994	Phase 2
NCT03099486	Fox Chase Cancer Center	Colorectal Cancer	October 6, 2017	Phase 2
NCT00482222	University of Southampton\|University Hospital Southampton NHS Foundation Trust	Colorectal Cancer\|Metastatic Cancer	February 2007	Phase 3
NCT02723994	Incyte Corporation\|Children´s Oncology Group	Leukemia	September 30, 2016	Phase 2
NCT04752696	Cardiff Oncology	Pancreatic Ductal Adenocarcinoma	May 3, 2021	Phase 2
NCT03121807	Kaohsiung Medical University Chung-Ho Memorial Hospital	Metastatic Gastric Cancer	September 1, 2014	Not Applicable
NCT04371224	Seoul National University Hospital	Pancreatic Cancer	June 23, 2020	Phase 2
NCT00049569	National Cancer Institute (NCI)	L1 Childhood Acute Lymphoblastic Leukemia\|L2 Childhood Acute Lymphoblastic Leukemia\|Non-T, Non-B Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia	January 2003	Not Applicable
NCT00210184	Institut Bergonié\|Novartis\|Sanofi-Synthelabo\|Aventis Pharmaceuticals	Gastric Cancer	July 21, 2004	Phase 2
NCT05564377	National Cancer Institute (NCI)	Advanced Malignant Solid Neoplasm\|Locally Advanced Malignant Solid Neoplasm	December 9, 2022	Phase 2
NCT01060007	Washington University School of Medicine	Rectal Neoplasms	November 2009	Phase 2
NCT01726452	Cancer Trials Ireland\|Southampton Clinical Trials Unit\|Region H Rigshospitalet\|Centre Hospitalier Régional, Universitaire de Lille	Adenocarcinoma of the Oesophagus\|Adenocarcinoma of the Oesophago-gastric Junction\|Oesophageal Tumours\|Junctional Tumours\|Oesophageal Cancer	January 24, 2013	Phase 3
NCT04141995	Jean Grem, MD\|National Cancer Institute (NCI)\|University of Nebraska	Pancreas Cancer\|Adenocarcinoma of the Pancreas	February 12, 2021	Phase 2
NCT05286814	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Metastatic Colorectal Cancer (Mcrc)\|Intrahepatic Cholangiocarcinoma (Icc)\|Colorectal Cancer\|Colorectal Neoplasms\|Cholangiocarcinoma\|Intrahepatic Bile Duct Cancer\|Bile Duct Cancer\|Bile Duct Neoplasms	October 24, 2022	Phase 2
NCT03883919	Washington University School of Medicine\|Ipsen	Pancreatic Cancer\|Pancreas Cancer\|Cancer of the Pancreas	July 11, 2019	Phase 1
NCT00002842	City of Hope Medical Center\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	September 1994	Phase 2
NCT01364376	Zhejiang University	Stomach Neoplasms	June 2011	Not Applicable
NCT00001576	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Colorectal Neoplasm\|Liver Neoplasm\|Neoplasm Metastasis	July 1997	Phase 1
NCT00103298	National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	December 2004	Phase 2
NCT00004231	Northwestern University\|National Cancer Institute (NCI)	Lymphoma	October 1999	Phase 2
NCT03336216	Bristol-Myers Squibb	Advanced Pancreatic Cancer	December 19, 2017	Phase 2
NCT00002593	Southwest Oncology Group\|National Cancer Institute (NCI)\|Cancer and Leukemia Group B\|Eastern Cooperative Oncology Group\|North Central Cancer Treatment Group	Colorectal Cancer	December 1994	Phase 3
NCT00632827	University of California, San Francisco\|Eisai Inc.\|Washington University School of Medicine	Peripheral T-Cell Lymphoma	July 1, 2008	Phase 2
NCT00009828	University of Pittsburgh\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	December 1999	Phase 1
NCT00835185	Eli Lilly and Company	Metastatic Colorectal Cancer	August 2007	Phase 2
NCT00507585	M.D. Anderson Cancer Center	Liver Cancer\|Advanced Solid Tumors	June 2006	Phase 1
NCT00276757	Histiocyte Society\|National Cancer Institute (NCI)	Childhood Langerhans Cell Histiocytosis	April 2001	Not Applicable
NCT00537823	Washington University School of Medicine	Colorectal Cancer\|Metastases	June 2007	Phase 2
NCT02345460	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Pancreatic Adenocarcinoma\|Poorly Differentiated Malignant Neoplasm\|Resectable Pancreatic Cancer\|Stage IA Pancreatic Cancer\|Stage IB Pancreatic Cancer\|Stage IIA Pancreatic Cancer\|Stage IIB Pancreatic Cancer\|Stage III Pancreatic Cancer\|Undifferentiated Pancreatic Carcinoma	September 2015	Phase 2
NCT01715233	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Metastatic Esophageal Cancer\|Gastroesophageal Cancer\|Gastric Cancer	December 2012	Phase 2
NCT03279237	Massachusetts General Hospital\|National Cancer Institute (NCI)	GastroEsophageal Cancer	October 24, 2017	Phase 1
NCT00118261	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	March 2005	Phase 1
NCT00002002	Lederle Laboratories\|NIH AIDS Clinical Trials Information Service	Pneumonia, Pneumocystis Carinii\|HIV Infections		Not Applicable
NCT00006468	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Colorectal Cancer	January 2000	Phase 3
NCT04607421	Pfizer\|Ono Pharmaceutical Co. Ltd\|Merck KGaA, Darmstadt, Germany	Neoplasms	December 21, 2020	Phase 3
NCT00009893	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Extrahepatic Bile Duct Cancer\|Gallbladder Cancer\|Liver Cancer	May 2001	Phase 2
NCT01479465	Gilead Sciences	Colorectal Cancer	December 2011	Phase 2
NCT03504397	Astellas Pharma Global Development, Inc.\|Astellas Pharma Inc	Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer\|Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer\|Metastatic Gastric Adenocarcinoma or Cancer\|Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma	June 21, 2018	Phase 3
NCT00408551	Goshen Health System\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	November 2005	Phase 2
NCT05047991	CSPC Ouyi Pharmaceutical Co., Ltd.	Pancreatic Cancer Non-resectable\|Pancreatic Cancer Metastatic	October 2021	Phase 2
NCT05472259	Belgian Group of Digestive Oncology\|University Hospital St Luc, Brussels	Metastatic Pancreatic Ductal Adenocarcinoma	May 25, 2022	Phase 2
NCT03314935	Incyte Corporation	Biliary Tract Cancer (BTC)\|Colorectal Cancer (CRC)\|Endometrial Cancer\|Gastroesophageal Cancer (GC)\|Ovarian Cancer\|Solid Tumors	November 21, 2017	Phase 1\|Phase 2
NCT01715363	Gustave Roussy, Cancer Campus, Grand Paris	Patients With Colorectal Cancer With Unresectable Synchronous Metastasis in Whom Resection of the Primitive Tumour is Indicated	July 2012	Phase 2
NCT00378456	Institute of Child Health	Trisiomy 21 (Down Syndrome)		Not Applicable
NCT01652482	Genentech, Inc.	Colorectal Cancer	October 2012	Phase 2
NCT01160419	Ludwig-Maximilians - University of Munich\|Sanofi	Gastric Cancer	December 2009	Phase 2
NCT04949256	Merck Sharp & Dohme LLC\|Eisai Inc.	Metastatic Esophageal Squamous Cell Carcinoma	July 28, 2021	Phase 3
NCT00557193	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Undifferentiated Leukemia\|Childhood T Acute Lymphoblastic Leukemia	January 14, 2008	Phase 3
NCT01046864	Bristol-Myers Squibb	Gastro-Intestinal Cancer	February 2010	Phase 1
NCT00000643	National Institute of Allergy and Infectious Diseases (NIAID)	Toxoplasmosis, Cerebral\|HIV Infections		Phase 2
NCT00005988	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Myeloma	February 2000	Phase 1
NCT00323583	Seattle Cancer Treatment and Wellness Center	Adenocarincoma of Pancreas\|Stage III Pancreatic Cancer\|Stage IVA Pancreatic Cancer\|Stage IVB Pancreatic Cancer	May 2006	Phase 2
NCT00294593	Institut Jerome Lejeune\|Fondation Jérôme Lejeune	Down Syndrome	October 2000	Phase 2\|Phase 3
NCT00002570	NCIC Clinical Trials Group\|North Central Cancer Treatment Group\|Canadian Cancer Trials Group	Colorectal Cancer	July 15, 1994	Phase 3
NCT00003049	Mayo Clinic\|National Cancer Institute (NCI)	Pancreatic Cancer	May 1997	Phase 3
NCT00450801	University of Miami	Lymphoma	April 2004	Phase 2
NCT00082706	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Bladder Cancer\|Urethral Cancer\|Urachal Cancer	April 2003	Phase 2
NCT01729481	Ludwig-Maximilians - University of Munich\|Roche Pharma AG	Metastatic Pancreatic Adenocarcinoma	July 2012	Phase 2
NCT00069095	Hoffmann-La Roche	Colorectal Cancer	July 2003	Phase 3
NCT01205711	Cardiff University	Colorectal Cancer	April 2010	Phase 2
NCT00005641	H. Lee Moffitt Cancer Center and Research Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	September 1997	Phase 2
NCT02578368	Krankenhaus Nordwest\|German Research Foundation\|Arbeitsgemeinschaft fur Internistische Onkologie	Gastric Cancer	February 2016	Phase 3
NCT00831181	Beth Israel Medical Center	Colorectal Cancer	July 2004	Phase 2
NCT00289445	University Hospital Tuebingen	Gastrointestinal Neoplasms\|Neoplasm Metastasis	September 1999	Phase 1\|Phase 2
NCT02340949	Grupo Espanol Multidisciplinario del Cancer Digestivo\|Pivotal S.L.	Rectal Cancer	January 2015	Phase 2
NCT00541125	Federation Francophone de Cancerologie Digestive	Colorectal Cancer	November 2007	Phase 2
NCT02720068	Merck Sharp & Dohme LLC	Neoplasms	May 2, 2016	Phase 1
NCT00988897	Sanofi	Colorectal Neoplasms	October 2009	Phase 2
NCT00176462	Rutgers, The State University of New Jersey\|National Cancer Institute (NCI)	Acute Lymphocytic Leukemia	February 2001	Phase 2
NCT03184870	Bristol-Myers Squibb	Colorectal Cancer\|Pancreatic Cancer	August 8, 2017	Phase 1\|Phase 2
NCT00003298	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Gastric Cancer	February 1999	Phase 2
NCT01443065	UNICANCER	Malignant Neoplasm of Esophagus\|Malignant Neoplasm of Stomach	January 2011	Phase 2
NCT00936832	Federation Francophone de Cancerologie Digestive	Colorectal Cancer\|Metastatic Cancer	April 2009	Phase 2
NCT03750786	Isofol Medical AB	Colo-rectal Cancer	December 18, 2018	Phase 3
NCT01229111	National Cancer Institute (NCI)	Adult Primary Cholangiocellular Carcinoma\|Advanced Adult Primary Liver Cancer\|Cholangiocarcinoma of the Extrahepatic Bile Duct\|Cholangiocarcinoma of the Gallbladder\|Localized Unresectable Adult Primary Liver Cancer\|Periampullary Adenocarcinoma\|Recurrent Adult Primary Liver Cancer\|Recurrent Extrahepatic Bile Duct Cancer\|Recurrent Gallbladder Cancer\|Unresectable Extrahepatic Bile Duct Cancer\|Unresectable Gallbladder Cancer	October 2010	Phase 2
NCT04083235	Ipsen	Metastatic Adenocarcinoma of the Pancreas	February 19, 2020	Phase 3
NCT00300404	Zentrum für Integrative Psychiatrie\|Stanley Medical Research Institute	Schizophrenia\|Major Depression	January 2002	Phase 3
NCT00642577	Hoffmann-La Roche	Colorectal Cancer	July 2007	Phase 3
NCT00002525	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Southwest Oncology Group\|Cancer and Leukemia Group B\|American College of Surgeons\|NSABP Foundation Inc\|Eastern Cooperative Oncology Group	Colorectal Cancer	August 1993	Phase 3
NCT01231399	City of Hope Medical Center\|National Cancer Institute (NCI)	Adenocarcinoma of the Esophagus\|Adenocarcinoma of the Gastroesophageal Junction\|Diffuse Adenocarcinoma of the Stomach\|Intestinal Adenocarcinoma of the Stomach\|Mixed Adenocarcinoma of the Stomach\|Recurrent Esophageal Cancer\|Recurrent Gastric Cancer\|Stage IV Esophageal Cancer\|Stage IV Gastric Cancer	February 2012	Phase 1\|Phase 2
NCT03007147	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia\|Mixed Phenotype Acute Leukemia\|T Acute Lymphoblastic Leukemia	July 28, 2017	Phase 3
NCT00940303	Hoffmann-La Roche	Colorectal Cancer	June 2009	Phase 2
NCT02319018	National Cancer Institute (NCI)	Malignant Digestive System Neoplasm	August 27, 2015	Phase 1
NCT00220064	Royal Marsden NHS Foundation Trust\|Aventis Pharmaceuticals	Upper Gastrointestinal Tumours	July 2000	Phase 2
NCT01164215	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer\|Diarrhea\|Neutropenia	February 2010	Phase 1
NCT00109837	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia	April 2005	Phase 2
NCT02883049	National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|Central Nervous System Leukemia\|Ph-Like Acute Lymphoblastic Leukemia\|Testicular Leukemia	February 27, 2012	Phase 3
NCT04251715	OHSU Knight Cancer Institute\|Oregon Health and Science University	Liver and Intrahepatic Bile Duct Carcinoma\|Stage III Intrahepatic Cholangiocarcinoma AJCC v8\|Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8\|Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8\|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8\|Unresectable Intrahepatic Cholangiocarcinoma	April 28, 2021	Phase 2
NCT02509286	University Hospital Schleswig-Holstein\|Clinical Trials Unit Freiburg\|University of Freiburg\|University of Leipzig\|University of Luebeck\|University of Hamburg-Eppendorf	Esophageal Adenocarcinoma (UICC TNM7)\|Adenocarcinoma of the Esophagogastric Junction	January 2016	Phase 3
NCT00408005	National Cancer Institute (NCI)	T Acute Lymphoblastic Leukemia\|T Lymphoblastic Lymphoma	January 22, 2007	Phase 3
NCT00039208	European Organisation for Research and Treatment of Cancer - EORTC	Colorectal Cancer	February 2002	Phase 2
NCT01590719	Hoffmann-La Roche\|Genentech, Inc.	Gastric Cancer	July 2012	Phase 2
NCT00237900	AstraZeneca	Subjects With Resectable Local or Locally Advanced, Non-Metastatic (T2-T4, N0-N3, M0; Stages II and III) and Histologically-Confirmed Intestinal GC	July 2003	Phase 1\|Phase 2
NCT00043004	European Organisation for Research and Treatment of Cancer - EORTC\|Arbeitsgruppe Lebermetastasen und Tumoren\|Institute of Cancer Research, United Kingdom	Colorectal Cancer\|Metastatic Cancer	May 2002	Phase 2
NCT04034173	Ludwig-Maximilians - University of Munich\|Amgen\|ClinAssess GmbH	Treatment Related Cancer	August 1, 2019	Phase 2
NCT00557102	National Cancer Institute, France\|University Hospital, Grenoble	Colorectal Cancer\|Metastatic Cancer	September 2007	Phase 2
NCT00002103	U.S. Bioscience\|NIH AIDS Clinical Trials Information Service	Pneumonia, Pneumocystis Carinii\|HIV Infections		Not Applicable
NCT00066274	UNICANCER	Colorectal Cancer	July 23, 2002	Phase 2
NCT00025142	Stanford University\|National Cancer Institute (NCI)	Colorectal Cancer	July 2001	Phase 2
NCT00002756	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	June 1996	Phase 2
NCT05382442	Akeso	Metastatic Colorectal Cancer	July 27, 2022	Phase 2
NCT00002692	Medical Research Council\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	December 1994	Phase 3
NCT03446872	Institut de Recherches Internationales Servier\|ADIR, a Servier Group company\|Servier	Metastatic Pancreatic Cancer	March 8, 2018
NCT03783936	Autumn McRee, MD\|EMD Serono\|University of North Carolina, Chapel Hill\|Hoosier Cancer Research Network	Gastric Adenocarcinoma\|Esophageal Adenocarcinoma\|Metastasis\|HER-2 Gene Amplification	January 24, 2019	Phase 2
NCT00003273	NYU Langone Health	Brain and Central Nervous System Tumors\|Neuroblastoma\|Retinoblastoma\|Sarcoma	November 1997	Phase 2
NCT00541112	UNICANCER	Colorectal Cancer	October 29, 2007	Phase 2
NCT01412879	Southwest Oncology Group\|National Cancer Institute (NCI)	Lymphoma	November 2011	Phase 2
NCT01068327	University of Nebraska\|National Cancer Institute (NCI)	Adenocarcinoma of the Pancreas\|Stage III Pancreatic Cancer	November 2007	Phase 1
NCT00002785	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	July 1996	Phase 2
NCT00851084	Sanofi	Colorectal Neoplasms\|Neoplasm Metastasis	February 2009	Phase 2
NCT02453464	Jiangsu Simcere Pharmaceutical Co., Ltd.	Metastatic Colorectal Cancer	August 2015	Phase 1
NCT01660711	NorthShore University HealthSystem\|University of Chicago	Pancreatic Adenocarcinoma	July 2012	Phase 2
NCT00005607	Robert H. Lurie Cancer Center\|National Cancer Institute (NCI)	Esophageal Cancer\|Gastric Cancer	February 2000	Phase 2
NCT02981628	Children´s Oncology Group\|National Cancer Institute (NCI)	Recurrent B Acute Lymphoblastic Leukemia\|Recurrent B Lymphoblastic Lymphoma\|Refractory B Acute Lymphoblastic Leukemia\|Refractory B Lymphoblastic Lymphoma	June 5, 2017	Phase 2
NCT02129257	Hellenic Cooperative Oncology Group\|Sanofi	Metastatic Colorectal Cancer	May 26, 2014	Phase 2
NCT00020917	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	February 2001	Phase 2
NCT00889343	AIO-Studien-gGmbH	Colorectal Neoplasms	March 2009	Phase 2
NCT00002955	University of Southern California\|National Cancer Institute (NCI)	Pancreatic Cancer	August 1995	Phase 2
NCT00642746	OHSU Knight Cancer Institute\|Genentech, Inc.\|OSI Pharmaceuticals	Metastatic Colorectal Cancer	March 2008	Phase 2
NCT04595929	St. Petersburg State Pavlov Medical University	Peritoneal Carcinomatosis\|Gastric Cancer	February 10, 2020	Not Applicable
NCT02037048	Case Comprehensive Cancer Center	Adenocarcinoma of the Esophagus\|Adenocarcinoma of the Gastroesophageal Junction\|Adenocarcinoma of the Gastric Cardia\|Stage IIIA Esophageal Cancer\|Stage IIIB Esophageal Cancer\|Stage IIIC Esophageal Cancer	February 10, 2014	Phase 2
NCT04068103	NRG Oncology\|National Cancer Institute (NCI)	Colon Adenocarcinoma\|Stage IIA Colon Cancer AJCC v8	December 16, 2019	Phase 2\|Phase 3
NCT01652196	John Hays\|Sanofi\|Ohio State University Comprehensive Cancer Center	Mucinous Adenocarcinoma of the Colon\|Mucinous Adenocarcinoma of the Rectum\|Signet Ring Adenocarcinoma of the Colon\|Signet Ring Adenocarcinoma of the Rectum\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	November 14, 2012	Phase 2
NCT03771560	University of California, San Francisco	Autism Spectrum Disorder	February 15, 2018	Phase 2\|Phase 3
NCT01280643	Fox Chase Cancer Center\|National Cancer Institute (NCI)	Metastatic Colorectal Cancer	March 2010	Not Applicable
NCT03085914	Incyte Corporation	Solid Tumor	May 2, 2017	Phase 1\|Phase 2
NCT02024607	Sumitomo Pharma Oncology, Inc.	Advanced Gastrointestinal Cancer	January 2014	Phase 1\|Phase 2
NCT05013164	Nishtar Medical University	Autism Spectrum Disorder	October 1, 2020	Phase 2
NCT02246049	EPS Corporation	Colorectal Neoplasms	May 2014	Phase 2
NCT01643499	University of Chicago\|National Cancer Institute (NCI)	Acinar Cell Adenocarcinoma of the Pancreas\|Adenocarcinoma of the Gallbladder\|Adenocarcinoma of Unknown Primary\|Adult Primary Cholangiocellular Carcinoma\|Advanced Adult Primary Liver Cancer\|Cholangiocarcinoma of the Extrahepatic Bile Duct\|Cholangiocarcinoma of the Gallbladder\|Diffuse Adenocarcinoma of the Stomach\|Duct Cell Adenocarcinoma of the Pancreas\|Intestinal Adenocarcinoma of the Stomach\|Localized Unresectable Adult Primary Liver Cancer\|Metastatic Carcinoma of Unknown Primary\|Metastatic Extrahepatic Bile Duct Cancer\|Mixed Adenocarcinoma of the Stomach\|Mucinous Adenocarcinoma of the Colon\|Mucinous Adenocarcinoma of the Rectum\|Newly Diagnosed Carcinoma of Unknown Primary\|Signet Ring Adenocarcinoma of the Colon\|Signet Ring Adenocarcinoma of the Rectum\|Stage III Pancreatic Cancer\|Stage IIIA Colon Cancer\|Stage IIIA Gallbladder Cancer\|Stage IIIA Gastric Cancer\|Stage IIIA Rectal Cancer\|Stage IIIB Colon Cancer\|Stage IIIB Gallbladder Cancer\|Stage IIIB Gastric Cancer\|Stage IIIB Rectal Cancer\|Stage IIIC Colon Cancer\|Stage IIIC Gastric Cancer\|Stage IIIC Rectal Cancer\|Stage IV Gastric Cancer\|Stage IV Pancreatic Cancer\|Stage IVA Colon Cancer\|Stage IVA Gallbladder Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Gallbladder Cancer\|Stage IVB Rectal Cancer\|Unresectable Extrahepatic Bile Duct Cancer	March 26, 2012	Phase 1
NCT00634504	BTG International Inc.	Osteosarcoma\|Leukemia\|Lymphoma	May 2008	Phase 1
NCT03586869	ImmunityBio, Inc.	Pancreatic Cancer	July 28, 2018	Phase 1\|Phase 2
NCT00043121	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	June 2002	Phase 1
NCT03043729	AIO-Studien-gGmbH\|Institut für Klinisch-Onkologische Forschung (IKF) Frankfurt\|Sanofi	Rectal Cancer\|Rectosigmoid Cancer	March 6, 2017	Phase 2
NCT01634555	Eli Lilly and Company	Solid Tumors	October 2012	Phase 2
NCT00003671	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	December 1998	Phase 2
NCT03607643	Leaf Vertical Inc.	Cancer of Pancreas\|Cancer of Liver\|Cancer of Rectum\|Cancer of Colon\|Cancer, Gall Bladder\|Myeloma Multiple\|Glioblastoma Multiforme	January 15, 2019	Phase 1\|Phase 2
NCT00954512	Merck Sharp & Dohme LLC	Neoplasms	September 25, 2009	Phase 1\|Phase 2
NCT04361708	University of Chicago	Pancreatic Adenocarcinoma\|Gastroesophageal Junction Adenocarcinoma\|Adenocarcinoma	May 8, 2020	Phase 1
NCT00400946	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Drug+Agent Toxicity by Tissue+Organ\|Leukemia	April 2005	Phase 3
NCT00057811	Children´s Oncology Group\|National Cancer Institute (NCI)	Childhood Burkitt Lymphoma\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Stage I Childhood Large Cell Lymphoma\|Stage I Childhood Small Noncleaved Cell Lymphoma\|Stage II Childhood Large Cell Lymphoma\|Stage II Childhood Small Noncleaved Cell Lymphoma\|Stage III Childhood Large Cell Lymphoma\|Stage III Childhood Small Noncleaved Cell Lymphoma\|Stage IV Childhood Large Cell Lymphoma\|Stage IV Childhood Small Noncleaved Cell Lymphoma\|Untreated Childhood Acute Lymphoblastic Leukemia	June 2004	Phase 2
NCT03167112	Petr Kavan\|McGill University Health Centre+Research Institute of the McGill University Health Centre	Pancreatic Cancer	July 3, 2017	Phase 2
NCT00653068	Children´s Oncology Group\|National Cancer Institute (NCI)	Childhood Atypical Teratoid+Rhabdoid Tumor	December 8, 2008	Phase 3
NCT01271582	Asan Medical Center	Stage IV Colorectal Cancer\|Gastric Cancer	January 2009	Phase 4
NCT03563157	ImmunityBio, Inc.	Colorectal Cancer Metastatic\|mCRC	May 25, 2018	Phase 1\|Phase 2
NCT04752163	M.D. Anderson Cancer Center	Hematopoietic and Lymphoid Cell Neoplasm\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Myelomonocytic Leukemia\|Recurrent Myelodysplastic Syndrome\|Refractory Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Refractory Chronic Myelomonocytic Leukemia\|Refractory Myelodysplastic Syndrome	March 25, 2021	Phase 1\|Phase 2
NCT00002489	Memorial Sloan Kettering Cancer Center	Extragonadal Germ Cell Tumor\|Ovarian Cancer	October 1991	Phase 2
NCT00865189	Hoffmann-La Roche	Rectal Cancer	October 23, 2007	Phase 2
NCT01397019	Per Pfeiffer\|Odense University Hospital	Pancreatic Cancer	April 2011	Phase 2
NCT00010088	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Extrahepatic Bile Duct Cancer\|Pancreatic Cancer	January 1999	Phase 2
NCT00002738	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Sarcoma	January 1996	Phase 2
NCT00000674	National Institute of Allergy and Infectious Diseases (NIAID)\|Upjohn\|Glaxo Wellcome	Toxoplasmosis, Cerebral\|HIV Infections		Not Applicable
NCT01494506	Merrimack Pharmaceuticals	Metastatic Pancreatic Cancer	November 2011	Phase 3
NCT00066846	National Cancer Institute (NCI)	Colorectal Cancer	August 2003	Phase 2
NCT00002865	Wake Forest University Health Sciences\|National Cancer Institute (NCI)	Leukemia	April 1995	Phase 2
NCT02640365	GERCOR - Multidisciplinary Oncology Cooperative Group\|Merrimack Pharmaceuticals	Unresectable Advanced Cancer	November 18, 2015	Phase 1
NCT02928224	Pfizer\|Merck KGaA, Darmstadt, Germany\|Pierre Fabre Medicament\|Ono Pharmaceutical Co. Ltd	BRAF V600E-mutant Metastatic Colorectal Cancer	October 13, 2016	Phase 3
NCT01413022	Washington University School of Medicine\|National Cancer Institute (NCI)	Pancreatic Neoplasms	April 2012	Phase 1
NCT01231802	Adherex Technologies, Inc.	Metastatic Breast Cancer	April 2011	Phase 2
NCT00422864	Peter MacCallum Cancer Centre, Australia	Rectal Cancer	October 2006	Phase 2
NCT04340141	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Pancreatic Adenosquamous Carcinoma\|Resectable Pancreatic Adenocarcinoma\|Pancreatic Cancer	July 1, 2020	Phase 3
NCT00070213	Medical Research Council\|University of Leeds	Colorectal Cancer	September 2003	Phase 3
NCT04864067	Servicio de Salud Metropolitano Sur Oriente	Rectal Cancer	June 9, 2021	Phase 2
NCT00005860	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Cancer	April 2000	Phase 1

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

* The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility

In Vitro:

H ₂ O : 50 mg/mL ( 97.75 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9550 mL	9.7752 mL	19.5503 mL
5 mM	0.3910 mL	1.9550 mL	3.9101 mL
10 mM	0.1955 mL	0.9775 mL	1.9550 mL

* Please refer to the solubility information to select the appropriate solvent.

References

Synonyms

L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1)

Glutamic acid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), L-

Calcium L-folinate

Calcium leucovorin

Calcium folinate

Calcium 5-formyltetrahydrofolate

Lederfoline

Leucovorin calcium

Leucovorin calcium salt

Folinic acid calcium salt

Rescuvolin

NSC 3590

Wellcovorin

Folidan

Folinate-SF calcium