[CAS NO. 149488-17-5] Trovirdine
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PRODUCTS SPECIFICATIONS [149488-17-5]
Distributor
Catalog
AS205607
Brand
Arctom Scientific
CAS
149488-17-5
DESCRIPTION [149488-17-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 337.24 |
| Molecular Formula | C13H13BrN4S |
| SMILES | S=C(NCCC1=NC=CC=C1)NC2=NC=C(Br)C=C2 |
For research use only. We do not sell to patients.
1 Publications Citing Use of MCE
Summary
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL ( 296.52 mM ; Need ultrasonic)
Preparing
Stock Solutions
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.9652 mL | 14.8262 mL | 29.6525 mL |
| 5 mM | 0.5930 mL | 2.9652 mL | 5.9305 mL |
| 10 mM | 0.2965 mL | 1.4826 mL | 2.9652 mL |
*
Please refer to the solubility information to select the appropriate solvent.
In Vivo:
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (7.41 mM); Clear solution
*
All of the co-solvents are available by MCE.
References
- [1] Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127.
- [2] Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.
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