[CAS NO. 1562-85-2] Gallocyanine chloride
PRODUCTS SPECIFICATIONS [1562-85-2]
DESCRIPTION [1562-85-2]
Overview
| MDL | MFCD00011926 |
|---|---|
| Molecular Weight | 336.73 |
| Molecular Formula | C15H13ClN2O5 |
| SMILES | OC1=C(O)C=C(C(O)=O)C2=C1[O+]=C3C=C(N(C)C)C=CC3=N2.[Cl-] |
Summary
Gallocyanine chloride, a synthetic blue dyestuff, blocks DKK1 inhibitory activity by disrupting DKK1/LRP6 interaction. Its association with LRP6 is weak (IC 50 of about 3 μM in the inhibition of DKK1 binding). Gallocyanine dye acts as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies [1] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 11.11 mg/mL ( 32.99 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.9697 mL | 14.8487 mL | 29.6974 mL |
| 5 mM | 0.5939 mL | 2.9697 mL | 5.9395 mL |
| 10 mM | 0.2970 mL | 1.4849 mL | 2.9697 mL |
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1.
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2.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 0.53 mg/mL (1.57 mM); Clear solution
Synonyms
