[CAS NO. 158913-22-5] SPDP-C6-NHSester
PRODUCTS SPECIFICATIONS [158913-22-5]
DESCRIPTION [158913-22-5]
Overview
| MDL | MFCD00083163 |
|---|---|
| Molecular Weight | 425.52 |
| Molecular Formula | C18H23N3O5S2 |
| SMILES | O=C(CCCCCNC(CCSSC1=NC=CC=C1)=O)ON2C(CCC2=O)=O |
Summary
IC50 & Target
|
Alkyl/ether |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 50 mg/mL ( 117.50 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.3501 mL | 11.7503 mL | 23.5007 mL |
| 5 mM | 0.4700 mL | 2.3501 mL | 4.7001 mL |
| 10 mM | 0.2350 mL | 1.1750 mL | 2.3501 mL |