[CAS NO. 1629265-17-3] K-RasG12C-IN-1

Name: K-RasG12C-IN-1
Brand: Arctom Scientific
SKU: AS906218

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PRODUCTS SPECIFICATIONS [1629265-17-3]

Distributor

Catalog

AS906218

Brand

Arctom Scientific

CAS

1629265-17-3

DESCRIPTION [1629265-17-3]

Overview

MDL	-
Molecular Weight	448.34
Molecular Formula	C22H23Cl2N3O3
SMILES	ClC(C=C(OC)C(NCC(N1CCN(C(C=C)=O)CC1)=O)=C2)=C2C3=CC=CC=C3Cl

For research use only. We do not sell to patients.

Summary

K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1. IC50 value: Target: K-ras G12C inhibitor

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 40 mg/mL ( 89.22 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2305 mL	11.1523 mL	22.3045 mL
5 mM	0.4461 mL	2.2305 mL	4.4609 mL
10 mM	0.2230 mL	1.1152 mL	2.2305 mL

* Please refer to the solubility information to select the appropriate solvent.