[CAS NO. 1672662-14-4]  PT2399

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PRODUCTS SPECIFICATIONS [1672662-14-4]

Distributor
Catalog
AS940534
Brand
Arctom Scientific
CAS
1672662-14-4

DESCRIPTION [1672662-14-4]

Overview

MDL-
Molecular Weight419.32
Molecular FormulaC17H10F5NO4S
SMILESO[C@@H]1C(F)(F)CC2=C(OC3=CC(C#N)=CC(F)=C3)C=CC(S(=O)(C(F)F)=O)=C12

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.3848 mL11.9241 mL23.8481 mL
5 mM0.4770 mL2.3848 mL4.7696 mL
10 mM0.2385 mL1.1924 mL2.3848 mL
50 mM0.0477 mL0.2385 mL0.4770 mL

Description

PT2399 is a potent and orally available antagonist of that selectively disrupts the heterodimerization of HIF-2α with .

Targets

HIF-2α [1]HIF-1β [1]

In vitro

PT2399 is a potent and orally available antagonist of HIF-2 that selectively disrupts the heterodimerization of HIF-2α with HIF-1β.