[CAS NO. 1698024-73-5] ARS-1323

Name: ARS-1323
Brand: Arctom Scientific
SKU: AS942453

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PRODUCTS SPECIFICATIONS [1698024-73-5]

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Catalog

AS942453

Brand

Arctom Scientific

CAS

1698024-73-5

MDL	MFCD31619312
Molecular Weight	430.84
Molecular Formula	C21H17ClF2N4O2
SMILES	O=C(C=C)N1CCN(C2=NC=NC3=C2C=C(Cl)C(C4=C(O)C=CC=C4F)=C3F)CC1

For research use only. We do not sell to patients.

ARS-1323, the racemate of ARS-1620, is a novel inhibitor of mutant K-ras G12C extracted from patent WO 2015054572 A1.

KRas G12C

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 100 mg/mL ( 232.10 mM ; Need ultrasonic)

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Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.80 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.80 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.80 mM); Clear solution

* All of the co-solvents are available by MCE.