[CAS NO. 1708971-72-5] FGFR4-IN-1
PRODUCTS SPECIFICATIONS [1708971-72-5]
DESCRIPTION [1708971-72-5]
Overview
| MDL | MFCD30489746 |
|---|---|
| Molecular Weight | 493.52 |
| Molecular Formula | C24H27N7O5 |
| SMILES | O=C(N1CCCC2=C1N=C(C=O)C(CN3C(COCC3)=O)=C2)NC4=NC=C(C#N)C(NCCOC)=C4 |
Summary
FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC 50 of 0.7 nM.
IC50 & Target
|
FGFR4 0.7 nM (IC 50 ) |
In Vitro
FGFR4-IN-1 significantly inhibits the proliferation of HuH-7 hepatocellular carcinoma cells with IC 50 of 7.8 nM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 6.4 mg/mL ( 12.97 mM ; Need warming)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.0263 mL | 10.1313 mL | 20.2626 mL |
| 5 mM | 0.4053 mL | 2.0263 mL | 4.0525 mL |
| 10 mM | 0.2026 mL | 1.0131 mL | 2.0263 mL |
