[CAS NO. 1802525-61-6] LRRK2 inhibitor 1

Name: LRRK2 inhibitor 1
Brand: Arctom Scientific
SKU: AS945179

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PRODUCTS SPECIFICATIONS [1802525-61-6]

Fulfillment

Catalog

AS945179

Brand

Arctom Scientific

CAS

1802525-61-6

MDL	-
Molecular Weight	397.43
Molecular Formula	C20H23N5O4
SMILES	CCOC1=NC(NC2=C(OC)C=C(C(N3CCOCC3)=O)C=C2)=NC4=C1C=CN4

For research use only. We do not sell to patients.

LRRK2 inhibitor 1 is a potent, selective and oral LRRK2 inhibitor with an pIC ₅₀ of 6.8.

pIC50: 6.8 nM (LRRK2) ^[1]

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 62.5 mg/mL ( 157.26 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (5.23 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.08 mg/mL (5.23 mM); Suspended solution; Need ultrasonic
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (5.23 mM); Clear solution

* All of the co-solvents are available by MCE.