[CAS NO. 18486-69-6] (−)-Myrtenal

Name: (−)-Myrtenal
Brand: Arctom Scientific
SKU: AS702316

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PRODUCTS SPECIFICATIONS [18486-69-6]

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Catalog

AS702316

Brand

Arctom Scientific

CAS

18486-69-6

DESCRIPTION [18486-69-6]

Overview

MDL	MFCD00074768
Molecular Weight	150.22
Molecular Formula	C10H14O
SMILES	CC1([C@@H]2C(C=O)=CC[C@H]1C2)C

For research use only. We do not sell to patients.

Summary

(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats ^[1] ^[2] .

In Vitro

(−)-Myrtenal ((1R)-(−)-Myrtenal; 0.1-5 mM; for 24 h) exerts strong cytotoxic effect (IC50 = 5.3 mM) on human colon tumour (HT29) and human normal colon epithelial cells (CCD 841 CoTr) ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

(−)-Myrtenal ((1R)-(−)-Myrtenal; orally; 80 mg/kg/day for 28 days) reveals decreased the levels of plasma glucose, improved the plasma insulin levels, up-regulation of IRS2, Akt and GLUT2 in liver and IRS2, Akt and GLUT4 protein expression in skeletal muscle in diabetic rats induced by single intraperitoneal injection of Streptozotocin (STZ) (40 mg/kg bw) ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Liquid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 665.69 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.6569 mL	33.2845 mL	66.5690 mL
5 mM	1.3314 mL	6.6569 mL	13.3138 mL
10 mM	0.6657 mL	3.3285 mL	6.6569 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (16.64 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (16.64 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (16.64 mM); Clear solution

* All of the co-solvents are available by MCE.