[CAS NO. 1862238-00-3] Sirt2-IN-1

Name: Sirt2-IN-1
Brand: Arctom Scientific
SKU: AS940568

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PRODUCTS SPECIFICATIONS [1862238-00-3]

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Catalog

AS940568

Brand

Arctom Scientific

CAS

1862238-00-3

MDL	-
Molecular Weight	557.69
Molecular Formula	C28H27N7O2S2
SMILES	O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CC4=CC=CC=C4)N=N3)=C2)S1)CSC5=NC(C)=CC(C)=N5

For research use only. We do not sell to patients.

Sirt2-IN-1 (Compound 9) is a sirtuin 2 ( Sirt2 ) inhibitor with an IC ₅₀ of 163 nM ^[1] .

SIRT2

163 nM (IC ₅₀ )

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 150 mg/mL ( 268.97 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (4.48 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (4.48 mM); Clear solution

* All of the co-solvents are available by MCE.