[CAS NO. 1946010-79-2] SAR405Renantiomer

Name: SAR405Renantiomer
Brand: Arctom Scientific
SKU: AS066307

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PRODUCTS SPECIFICATIONS [1946010-79-2]

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Catalog

AS066307

Brand

Arctom Scientific

CAS

1946010-79-2

MDL	-
Molecular Weight	443.85
Molecular Formula	C19H21ClF3N5O2
SMILES	O=C1C=C(N2[C@H](C)COCC2)N=C3N1CC[C@H](C(F)(F)F)N3CC4=CC(Cl)=CN=C4

For research use only. We do not sell to patients.

SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is a PIK3C3/Vps34 inhibitor.

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 100 mg/mL ( 225.30 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.63 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.63 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.63 mM); Clear solution

* All of the co-solvents are available by MCE.