[CAS NO. 19983-28-9] VPC-14228

Name: VPC-14228
Brand: Arctom Scientific
SKU: AS412716

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PRODUCTS SPECIFICATIONS [19983-28-9]

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Catalog

AS412716

Brand

Arctom Scientific

CAS

19983-28-9

DESCRIPTION [19983-28-9]

Overview

MDL	MFCD00628805
Molecular Weight	246.33
Molecular Formula	C13H14N2OS
SMILES	N1(C2=NC(C3=CC=CC=C3)=CS2)CCOCC1

For research use only. We do not sell to patients.

Summary

VPC-14228 is a potent androgen receptor DNA binding domain ( AR-DBD ) inhibitor that interferes with the interaction of AR with androgen response elements and effectively blocks AR transcriptional activity. VPC-14228 can be used in prostate cancer research ^[1] .

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References

[1] Kush Dalal, et al. Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer. J Biol Chem. 2014 Sep 19;289(38):26417-26429.