[CAS NO. 202808-11-5] MRZ 2-514
PRODUCTS SPECIFICATIONS [202808-11-5]
DESCRIPTION [202808-11-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 308.09 |
| Molecular Formula | C11H6BrN3O3 |
| SMILES | O=C1NNC(C2=C1C=C3C=C(Br)C=CC3=[N+]2[O-])=O |
1 Publications Citing Use of MCE
Summary
MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with K i of 33 μM.
IC50 & Target
Ki: 33 μM (glycineB) [1]
In Vitro
MRZ 2-514 has IC 50 values against peak AMPA-induced currents of 72.7 μM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MRZ 2/514 has anticonvulsive action in the MES model in mice, and the effect is prolonged by probenecid [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
