[CAS NO. 205110-48-1] Cethromycin

Name: Cethromycin
Brand: Arctom Scientific
SKU: AS127988

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PRODUCTS SPECIFICATIONS [205110-48-1]

Distributor

Catalog

AS127988

Brand

Arctom Scientific

CAS

205110-48-1

DESCRIPTION [205110-48-1]

Overview

MDL	-
Molecular Weight	765.93
Molecular Formula	C42H59N3O10
SMILES	O[C@H]1[C@@](O[C@@H]([C@@](OC/C=C\C2=CC(C=CC=C3)=C3N=C2)(C)C[C@@H](C)C4=O)[C@@H](C)C([C@@H](C)C(O[C@H](CC)[C@](OC(N5)=O)(C)[C@@]5([H])[C@H]4C)=O)=O)([H])O[C@H](C)C[C@@H]1N(C)C

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Research Square Print. December 5th, 2022.

Summary

Cethromycin (ABT-773) is a ketolide antibiotic ^[1] .

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT00336544	Advanced Life Sciences, Inc.	Pneumonia	June 2006	Phase 3
NCT00336505	Advanced Life Sciences, Inc.	Pneumonia	December 2005	Phase 3

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 130.56 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3056 mL	6.5280 mL	13.0560 mL
5 mM	0.2611 mL	1.3056 mL	2.6112 mL
10 mM	0.1306 mL	0.6528 mL	1.3056 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] English ML, et al. Cethromycin versus clarithromycin for community-acquired pneumonia: comparative efficacyand safety outcomes from two double-blinded, randomized, parallel-group, multicenter, multinational noninferiority studies. Antimicrob Agents Chemot

Synonyms

2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 4-ethyloctahydro-3a,7,9,11,13,15-hexamethyl-11-[[3-(3-quinolinyl)-2-propenyl]oxy]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-

(3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyloctahydro-3a,7,9,11,13,15-hexamethyl-11-[[3-(3-quinolinyl)-2-propenyl]oxy]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-2H-oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone

ABT 773

Abbott 195773

Cethromycin

A 195773