[CAS NO. 2055042-71-0] N-(Propargyl-PEG4)-biocytin

Name: N-(Propargyl-PEG4)-biocytin
Brand: Arctom Scientific
SKU: AS035026

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PRODUCTS SPECIFICATIONS [2055042-71-0]

Distributor

Catalog

AS035026

Brand

Arctom Scientific

CAS

2055042-71-0

DESCRIPTION [2055042-71-0]

Overview

MDL	MFCD30182023
Molecular Weight	614.75
Molecular Formula	C28H46N4O9S
SMILES	C#CCOCCOCCOCCOCCC(N[C@@H](CCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)C(O)=O)=O

For research use only. We do not sell to patients.

Summary

N-(Propargyl-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs ^[1] .

IC50 & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Synonyms

7,10,13,16-Tetraoxa-3-azanonadec-18-ynoic acid, 2-[4-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]butyl]-4-oxo-, (2S)-