[CAS NO. 212631-67-9] PD184161

Name: PD184161
Brand: Arctom Scientific
SKU: AS954844

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PRODUCTS SPECIFICATIONS [212631-67-9]

Distributor

Catalog

AS954844

Brand

Arctom Scientific

CAS

212631-67-9

DESCRIPTION [212631-67-9]

Overview

MDL	-
Molecular Weight	557.56
Molecular Formula	C17H13BrClF2IN2O2
SMILES	N(C1=C(C(NOCC2CC2)=O)C=C(Br)C(F)=C1F)C3=C(Cl)C=C(I)C=C3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.7935 mL	8.9676 mL	17.9353 mL
5 mM	0.3587 mL	1.7935 mL	3.5871 mL
10 mM	0.1794 mL	0.8968 mL	1.7935 mL
50 mM	0.0359 mL	0.1794 mL	0.3587 mL

Description

PD184161, an orally active inhibitor with IC50 of 10-100 nM in a time- and concentration-dependent manner, inhibits cell proliferation and induces apoptosis, and produces depressive-like behavior.

Targets

MEK ^[1]

References

[1] Klein PJ, et al. Neoplasia. 2006 Jan;8(1):1-8.

Synonyms

Benzamide, 5-bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-

5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide

5-Bromo-2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide

PD 184161