[CAS NO. 2128735-27-1]  N-Mal-N-bis(PEG4-NH-Boc)

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PRODUCTS SPECIFICATIONS [2128735-27-1]

Fulfillment
Catalog
AS014660
Brand
Arctom Scientific
CAS
2128735-27-1

DESCRIPTION [2128735-27-1]

Overview

MDLMFCD31536761
Molecular Weight806.94
Molecular FormulaC37H66N4O15
SMILESO=C(OC(C)(C)C)NCCOCCOCCOCCOCCN(C(CCN1C(C=CC1=O)=O)=O)CCOCCOCCOCCOCCNC(OC(C)(C)C)=O

For research use only. We do not sell to patients.

Summary

N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1] .


IC50 & Target

PEGs

Alkyl/ether


In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Viscous liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month


Synonyms

5,8,11,14,20,23,26,29-Octaoxa-2,17,32-triazatritriacontanedioic acid, 17-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-, 1,33-bis(1,1-dimethylethyl) ester