[CAS NO. 219931-45-0]  Aminoacyl tRNA synthetase-IN-1

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PRODUCTS SPECIFICATIONS [219931-45-0]

Distributor
Catalog
AS904664
Brand
Arctom Scientific
CAS
219931-45-0

DESCRIPTION [219931-45-0]

Overview

MDL-
Molecular Weight459.48
Molecular FormulaC16H25N7O7S
SMILESO[C@@H]1[C@@H](COS(=O)(NC([C@H]([C@@H](C)CC)N)=O)=O)O[C@@H](N2C(N=CN=C3N)=C3N=C2)[C@@H]1O

For research use only. We do not sell to patients.

Summary

Aminoacyl tRNA synthetase-IN-1 is a bacterial aminoacyl tRNA synthetase ( aaRS ) inhibitor.


IC50 & Target

aaRS [1]


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 65 mg/mL ( 141.46 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1764 mL 10.8819 mL 21.7637 mL
5 mM 0.4353 mL 2.1764 mL 4.3527 mL
10 mM 0.2176 mL 1.0882 mL 2.1764 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 1.08 mg/mL (2.35 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1.08 mg/mL (2.35 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 1.08 mg/mL (2.35 mM); Clear solution

* All of the co-solvents are available by MCE.