[CAS NO. 222716-34-9] SZL P1-41
PRODUCTS SPECIFICATIONS [222716-34-9]
DESCRIPTION [222716-34-9]
Overview
| MDL | MFCD00711481 |
|---|---|
| Molecular Weight | 420.52 |
| Molecular Formula | C24H24N2O3S |
| SMILES | O=C1C(C2=NC3=CC=CC=C3S2)=COC4=C(CN5CCCCC5)C(O)=C(CC)C=C14 |
8 Publications Citing Use of MCE
Summary
IC50 & Target
Skp2 [1]
In Vitro
SZL P1-41 (5-20μM; 24 hours) induces endogenous p27 protein expression in PC3 cells and also induced expression of p21, another Skp2 substrate [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
SZL P1-41 (40-80 mg/kg; i.p.) displays a potent effect on inhibiting prostate and lung tumor growth in Nude mice bearing A549 and PC3 tumor xenografts [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 2.5 mg/mL ( 5.95 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.3780 mL | 11.8900 mL | 23.7801 mL |
| 5 mM | 0.4756 mL | 2.3780 mL | 4.7560 mL |
| 10 mM | --- | --- | --- |
References
