[CAS NO. 2229976-21-8] (S,R,S)-AHPC-Me-C5-COOH

Name: (S,R,S)-AHPC-Me-C5-COOH
Brand: Arctom Scientific
SKU: AS896885

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [2229976-21-8]

Distributor

Catalog

AS896885

Brand

Arctom Scientific

CAS

2229976-21-8

DESCRIPTION [2229976-21-8]

Overview

MDL	MFCD33029229
Molecular Weight	586.74
Molecular Formula	C30H42N4O6S
SMILES	O=C(N[C@H](C1=CC=C(C2=C(C)N=CS2)C=C1)C)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCC(O)=O)=O)=O)C[C@H](O)C3

For research use only. We do not sell to patients.

Summary

(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604) ^[1] .

IC50 & Target

VHL

In Vitro

DT2216 is a selective B-cell lymphoma extra large (BCL-XL) PROTAC degrader ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

References

[1] Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.