[CAS NO. 2231744-29-7]  MT-802

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PRODUCTS SPECIFICATIONS [2231744-29-7]

Distributor
Catalog
AS951088
Brand
Arctom Scientific
CAS
2231744-29-7

DESCRIPTION [2231744-29-7]

Overview

MDL-
Molecular Weight787.82
Molecular FormulaC41H41N9O8
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.2693 mL6.3466 mL12.6933 mL
5 mM0.2539 mL1.2693 mL2.5387 mL
10 mM0.1269 mL0.6347 mL1.2693 mL
50 mM0.0254 mL0.1269 mL0.2539 mL

Description

MT-802 is a potent PROTAC that induces knockdown. MT-802 recruits BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome. MT-802 has potential for treatment of C481S mutant chronic lymphocytic leukemia (CLL).

Targets

BTK [1]