[CAS NO. 23694-17-9] Sultopridehydrochloride
PRODUCTS SPECIFICATIONS [23694-17-9]
DESCRIPTION [23694-17-9]
Overview
| MDL | MFCD01319147 |
|---|---|
| Molecular Weight | 390.93 |
| Molecular Formula | C17H27ClN2O4S |
| SMILES | O=C(NCC1N(CC)CCC1)C2=CC(S(=O)(CC)=O)=CC=C2OC.Cl |
1 Publications Citing Use of MCE
Summary
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor .
IC50 & Target
Dopamine D2 receptor [1]
In Vivo
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05) [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H 2 O : 50 mg/mL ( 127.90 mM ; Need ultrasonic)
DMSO : 50 mg/mL ( 127.90 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.5580 mL | 12.7900 mL | 25.5800 mL |
| 5 mM | 0.5116 mL | 2.5580 mL | 5.1160 mL |
| 10 mM | 0.2558 mL | 1.2790 mL | 2.5580 mL |
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1.
Add each solvent one by one: PBS
Solubility: 140 mg/mL (358.12 mM); Clear solution; Need ultrasonic
Synonyms
