[CAS NO. 24584-09-6] Dexrazoxane
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS [24584-09-6]
Fulfillment
Catalog
AS008006
Brand
Arctom Scientific
CAS
24584-09-6
DESCRIPTION [24584-09-6]
Overview
| MDL | MFCD00866449 |
|---|---|
| Molecular Weight | 268.27 |
| Molecular Formula | C11H16N4O4 |
| SMILES | C([C@H](C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.7276 mL | 18.6379 mL | 37.2759 mL |
| 5 mM | 0.7455 mL | 3.7276 mL | 7.4552 mL |
| 10 mM | 0.3728 mL | 1.8638 mL | 3.7276 mL |
| 50 mM | 0.0746 mL | 0.3728 mL | 0.7455 mL |
Description
Dexrazoxane (ICRF-187) is an anticancer drug able to block mitosis and to arrest dividing cells. It is an iron chelator and provides cardioprotection against anthracycline toxicity.
In vitro
Topoisomerase 2 (Top2) inhibition with dexrazoxane combined with dBET6 in HeLa cells increases DNA damage signaling at proximal time points.
Synonyms
2,6-Piperazinedione, 4,4′-[(1S)-1-methyl-1,2-ethanediyl]bis-
2,6-Piperazinedione, 4,4′-propylenedi-, (+)-
2,6-Piperazinedione, 4,4′-(1-methyl-1,2-ethanediyl)bis-, (S)-
4,4′-[(1S)-1-Methyl-1,2-ethanediyl]bis[2,6-piperazinedione]
(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
ICRF 187
NSC 169780
(S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane
Dexrazoxane
ADR 529
(S)-4,4′-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.